Non-invasive glucose measuring device and method for measuring blood glucose
First Claim
1. A glucose measuring device for determining the concentration of glucose in fluid within a body part of a subject, comprising:
- a) a first light source emitting near infrared or infrared light having a wavelength of between 650 and 1300 nm to illuminate the fluid, a second light source emitting near infrared or infrared light having a second wavelength of between 650 and 1300 nm to illuminate the fluid which is different from the wavelength of said first light source, and at least one receptor associated with said light sources for receiving light emitted by said light sources and transmitted through the fluid and body part of the subject and generating transmission signals representing the light transmitted from said first and second light sources;
b) a support piece having a first plate for supporting said light sources, and a second plate movable with respect to said first plate for supporting said receptor associated with said light sources;
c) said support piece adapted to place a body part of a subject intermediate said first and second plates and to alternately illuminate the body part and fluid using one of said light sources; and
d) a signal analyzer interconnected with said receptor for receiving said transmission signals and for determining from the transmission signals the glucose concentration in the fluid within the illuminated body part.
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Accused Products
Abstract
A glucose measuring device for determining the concentration of glucose in intravascular blood within a body part of a subject. The device includes light sources having a wavelength of 650, 880, 940 or 1300 nm to illuminate the fluid. Receptors associated with the light sources for receiving light and generating a transmission signal representing the light transmitted are also provided. A support piece is including for supporting the light sources associated with their respective light sources. The support piece is adapted to engage a body part of a subject. Finally, a signal analyzer, which includes a trained neural network, determines the glucose concentration in the blood of the subject. A method for determining the glucose concentration is also provided which calibrates a measuring device and sets the operating current for illuminating the light sources during operation of the device. Once a transmission signal is generated by receptors receiving light via the light sources and illuminated blood, and the high and low values from each of the signals are stored in the device, and averaged to obtain a single transmission value for each of the light sources. The averaged values are then analyzed to determine the glucose concentration, which value is displayed on the device.
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Citations
15 Claims
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1. A glucose measuring device for determining the concentration of glucose in fluid within a body part of a subject, comprising:
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a) a first light source emitting near infrared or infrared light having a wavelength of between 650 and 1300 nm to illuminate the fluid, a second light source emitting near infrared or infrared light having a second wavelength of between 650 and 1300 nm to illuminate the fluid which is different from the wavelength of said first light source, and at least one receptor associated with said light sources for receiving light emitted by said light sources and transmitted through the fluid and body part of the subject and generating transmission signals representing the light transmitted from said first and second light sources; b) a support piece having a first plate for supporting said light sources, and a second plate movable with respect to said first plate for supporting said receptor associated with said light sources; c) said support piece adapted to place a body part of a subject intermediate said first and second plates and to alternately illuminate the body part and fluid using one of said light sources; and d) a signal analyzer interconnected with said receptor for receiving said transmission signals and for determining from the transmission signals the glucose concentration in the fluid within the illuminated body part. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for determining the glucose concentration in intravascular blood within a body part of a subject comprising the steps of:
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i) calibrating a non-invasive glucose measuring device by; a) measuring the pulse waveform of the subject using one of a first or second light source; b) incrementally increasing an electrical current powering one of said first or second light sources, incrementally reading a transmission signal generated in a first or second receptor, and comparing said incremental transmission signals until a predetermined desired quality of transmission signal is received from said first or second light source; c) establishing said electrical current which resulted in the desired quality of transmission signal as the operating current for powering said first and second light sources during operation of said glucose measuring device; ii) operating said non-invasive glucose measuring device by; a) illuminating intravascular blood within a body part using first or second light sources positioned adjacent to and engaging the body part for multiple consecutive readings, said light sources having different wavelengths of between 650 and 1300 nm and being powered at the established electrical current; b) generating a transmission signal in first or second receptors from each of said first or second light sources via the illuminated intravascular blood of the body part, said first or second receptors positioned adjacent to and engaging the body part on an opposite side of the body part from the first and second light sources, respectively; c) storing high and low values from each of the multiple transmission signals from each of the light sources; d) averaging each of the multiple sets of high and low values from each transmission signal generated to obtain a single transmission value for each of said light sources; e) analyzing the averaged transmission signal values to determine the glucose concentration in the intravascular blood within the body part; and f) displaying the glucose concentration. - View Dependent Claims (13, 14, 15)
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Specification