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Passive measurement of isotopes to monitor health

  • US 5,912,178 A
  • Filed: 02/16/1994
  • Issued: 06/15/1999
  • Est. Priority Date: 02/16/1994
  • Status: Expired due to Term
First Claim
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1. A method of determining the presence of a catabolic state in an essentially isotopically enriched animal, comprising the steps of:

  • collecting a sample selected from the group consisting of breath, whole blood, blood immunoglobin, hemoglobin, urine, hair tissue, feathers, horns, hooves, nails, skin, shells and membranes from the animal;

    measuring the relative amount of a first isotope to a second isotope in the sample;

    the isotopes being the pair 13 C and 12 C, or being the pair 15 N and 14 N;

    comparing said measured relative amount of the sample with a relative amount of said pair isotopes in a comparison specimen other than the sample; and

    determining from the comparison step whether a catabolic state is present in the animal wherein the change in the isotope ratios either increasing or decreasing is indicative of a catabolic state.

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