System for introducing a fluid into the uterus of an animal

• US 5,916,144 A
• Filed: 11/05/1997
• Issued: 06/29/1999
• Est. Priority Date: 05/09/1995
• Status: Expired due to Fees

• Current Assignee: Curators of the University of Missouri (University of Missouri)
• Original Assignee: Curators of the University of Missouri (University of Missouri)
• Inventors: Day, Billy N., Li, Jiewen, Rieke, August, Prather, Randall S.
• Primary Examiner(s): Apley, Richard J.
• Assistant Examiner(s): YU, JUSTINE ROMANG
• Application Number:
  US08/964,833
• Time in Patent Office: 601 Days
• Field of Search: 600/562, 600/564, 600/565, 600/567, 600/563, 600/34, 600/35, 600/33, 600/591, 606/119, 606/126, 606/127, 606/125, 606/159, 604/170, 604/53, 604/55, 604/96, 604/280, 604/49, 604/54, 604/171, 604/165, 604/169, 604/264, 128/898
• US Class Current: 600/34
• CPC Class Codes: A61B 17/4241 Instruments for manoeuvring or retracting the uterus, e.g. during laparoscopic surgery
• CPC Class Codes: A61B 17/43 for artificial insemination
• CPC Class Codes: A61D 19/027 Devices for injecting semen into animals, e.g. syringes, guns, probes
• CPC Class Codes: A61D 19/04 for embryo transplantation

Abstract

This invention relates to a system for penetrating the uterus of an animal during a non-surgical procudure, the uterus having a cervix leading to a uterus body. The system comprises a probe having a long tubular body with a central longitudinal axis, open forward and rearward ends, and a probing member projecting forward and laterally outward beyond the forward end of the probe body. The probe is inserted, forward end first, inside the cervix of said animal, and the probe body is manipulated to gently maneuver the probing member in a forward direction through the cervix to a position in which the probing member and the forward open end of the probe body are adjacent the body of the uterus.

Claims

1. A system for introducing a fluid comprising either semen or a fluid medium containing embryos into the uterus of an animal, said uterus having a cervix leading to a uterus body, said system comprising

a probe having a long tubular body with a central longitudinal axis, open forward and rearward ends, and a probing member curving forwardly and laterally outwardly beyond the forward end of the body, said probe being configured for insertion of the probing member and probe body, forward end first, inside the cervix of said animal and for manipulation of the probing member and probe body to gently maneuver the probing member in a forward direction through the cervix to a position in which the probing member and the forward open end of the probe body are adjacent the body of the uterus, and

a fluid carrier for carrying fluid to be placed in the uterus of the animal, said fluid carrier being sized for insertion in and forward movement trough the probe body to a fluid release position for release of the fluid into the uterus.

2. A system as set forth in claim 1 wherein said fluid carrier comprises a cannula having a closed forward end, a rearward end, an overall length greater than that of the probe, and a fluid release port adjacent the forward end of the cannula, said cannula being sized in cross-section for insertion into and sliding movement within said probe, said fluid carrier further comprising a fluid holder having a fluid outlet, said holder being sized for insertion in said cannula and being adapted for release of fluid through the outlet of the holder into the cannula for exit through said fluid release port.

3. A system as set forth in claim 2 further comprising a ram sized for insertion through the rearward end of said cannula, said ram being manually pushable in a forward direction through said cannula to force fluid out of the fluid holder and into the fluid cannula for release into the uterus via said fluid release port.

4. A system as set forth in claim 2 further comprising a gripping mechanism for gripping said cannula and releasably holding the cannula in selected axial positions relative to the probe.

5. A system as set forth in claim 4 wherein said gripping mechanism comprises a gripping device on the probe movable between a non-gripping position and a gripping position in which the gripping device is engageable with said cannula to grip the cannula, and an actuator manually movable between an actuating position for moving the gripping device to said gripping position and a release position for enabling said gripping device to move to its non-gripping position.

6. A system as set forth in claim 5 wherein said gripping device comprises at least one gripping finger movable generally radially inwardly and outwardly relative to a central longitudinal axis of the probe between said gripping and non-gripping positions, and wherein said actuator comprises a sleeve slidable axially relative to said central longitudinal axis over said at least one gripping finger, said sleeve being slidable in a first direction for causing said at least one gripping finger to move to said gripping position and in a second direction for enabling said at least one gripping finger to move to said non-gripping position.

7. A system as set forth in claim 1 wherein said fluid carrier comprises a tubular straw having an open rearward end for connection to an aspirator, the straw further having an open forward end for aspiration of fluid into the straw, the fluid carrier further comprising a long flexible guide member for guiding the carrier into a fluid release position in the uterus, and a tubular connector for connecting the guide member to the open front end of the straw, said tubular connector having an outlet port in fluid communication with the open forward end of the straw for release of fluid in the straw through said outlet port.

8. A system as set forth in claim 7 further comprising an internal stop in the tubular body of the probe, and an external abutment on the tubular connector of the carrier engageable with said internal abutment on the probe body for limiting forward movement of the carrier relative to the probe body, said abutment and stop being so located that when they are in engagement the outlet port of the connector and said guide member are disposed forwardly beyond the forward open end of the probe body.

9. A method of effecting the non-surgical introduction of fluid comprising either semen or a fluid medium containing embryos into the uterus of an animal, said method involving the use of a probe having a long tubular body with a central longitudinal axis and an open forward end, and a probing member projecting in a generally non-axial direction from the probe body generally adjacent its forward end and extending outward beyond the forward end of the probe body, said method comprising the steps of

inserting the probe, forward end first, into a cervix of the uterus of the animal,

pushing the probe in a forward direction while simultaneously rotating the probe body about the central longitudinal axis of the probe body to cause said probing member to gently maneuver through the cervix until the probe body is in a forward position in which the forward end of the probe body is in the uterus of the animal,

placing a fluid carrier carrying fluid inside the probe body, and

releasing fluid from tie carrier into the uterus when the probe body is in its said forward position.

10. A method as set forth in claim 9 wherein said carrier comprises a fluid holder having a fluid outlet, and a cannula having a closed forward end, a rearward end, an overall length greater than that of said probe, and a fluid release port adjacent the forward end of the cannula, said cannula being sized in cross-section for insertion into and sliding movement within said probe, said method further comprising inserting said fluid holder in said cannula, inserting the cannula into said probe body to an intermediate position in which the forward end of the cannula is adjacent the forward open end of the probe body and blocks the open forward end of the probe body, inserting the probe with said cannula and fluid holder therein into the cervix of the animal and moving the probe body to its said forward position, and then, while holding the probe generally stationary, moving the cannula further forward to a fluid release position in which said fluid release port is disposed beyond the forward end of the probe body, and releasing the fluid through the outlet of the holder into the cannula for exit through said fluid release port into the uterus.

11. A method as set forth in claim 10 further comprising holding the cannula stationary relative to the probe body in said intermediate position until said probe is in its said forward position.