Bodily sample collection balloon catheter

• US 5,919,145 A
• Filed: 01/24/1997
• Issued: 07/06/1999
• Est. Priority Date: 12/30/1993
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Corporation
• Original Assignee: Boston Scientific Corporation
• Inventors: Sahatjian, Ronald A.
• Primary Examiner(s): STRIGHT, RONALD K
• Application Number:
  US08/787,303
• Time in Patent Office: 893 Days
• Field of Search: 128/763, 128/765, 128/749, 128/752, 128/756, 128/757, 128/758-760, 604/96, 604/101, 604/104, 604/265, 604/266, 604/1-3, 606/191-198, 606/159, 606/160, 206/570, 206/571, 206/363, 206/438, 600/562, 600/565, 600/569-573, 600/576, 600/578
• US Class Current: 600/572
• CPC Class Codes: A61B 10/04 Endoscopic instruments
• CPC Class Codes: A61M 2025/109 having balloons for removing solid matters, e.g. by grasping or scraping plaque, thrombus or other matters that obstruct the flow
• CPC Class Codes: A61M 25/104 used for angioplasty

Abstract

Treating a patient by collecting a bodily sample from deep within the body of a patient and collecting the sample outside the body to facilitate treatment of the patient. A sampling probe is provided in the form of an elongate catheter having a proximal portion that remains outside the body and a distal portion that can be located within the body. The distal portion includes a polymer on its outer surface capable of receiving a substantial amount of bodily sample. The catheter is positioned within the body and the sample is taken by exposing the polymer by placing it in proximity within a desired location so that the bodily sample is received by the polymer. The catheter is removed from the patient and the sample is collected outside the body.

Claims

1. A kit for collecting a sample from a blood vessel of a patient that can be analyzed to determine a physiological function, comprising the following components packaged together:

an elongated vascular sampling catheter having a proximal portion that remains outside the body and a distal portion that can be located in the blood vessel, said distal portion including an expandable portion that can be selectively expanded to larger diameters and contracted to smaller diameters, said expandable portion including a swellable hydrogel polymer composed of a cross-linked polymer matrix capable of receiving substantial amounts of said sample, said hydrogel polymer comprising a probe which binds to and retains a target bodily component, and

an apparatus for facilitating analysis of said sample to determine the physiological function.

2. The kit of claim 1 wherein said hydrogel is a polyacrylic acid hydrogel having a thickness of about 10-50 μ

m in the swelled state.

3. The kit of claim 1 wherein said kit includes a protective sheath for protecting said hydrogel from substantial exposure to said vessel prior to and after receiving said sample.

4. The kit of claim 1 wherein said vascular catheter is a balloon dilatation catheter.