Catheter with slidable balloon

• US 5,919,163 A
• Filed: 07/14/1997
• Issued: 07/06/1999
• Est. Priority Date: 07/14/1997
• Status: Expired due to Term

• Current Assignee: Delcath Systems, Inc.
• Original Assignee: Delcath Systems, Inc.
• Inventors: Glickman, Morton G.
• Primary Examiner(s): Coggins, Wynn Wood
• Assistant Examiner(s): KENNEDY, SHARON E
• Application Number:
  US08/891,744
• Time in Patent Office: 722 Days
• Field of Search: 604/101, 604/102, 604/96, 604/284
• US Class Current: 604/101.05
• CPC Class Codes: A61M 1/3615 Cleaning blood contaminated by local chemotherapy of a body part temporarily isolated from the blood circuit
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters

Abstract

The instant invention provides a novel double balloon catheter which includes a first fixed balloon on the cranial end of the catheter; a second slidable balloon positioned around the catheter and spaced from the first fixed balloon; and, structure for enabling the second balloon to slide along the plastic tube between a first position defining a minimum distance between the first balloon and the second balloon, and a second position defining a maximum distance between the first balloon and the second balloon. The invention also contemplates a novel method of using the catheter.

Claims

1. In an apparatus for treating a tumor in the body of a patient, including a first catheter designed, sized and dimensioned for percutaneous insertion into the blood vessel receiving the blood from said tumor, further including (a) a plastic tube having a cranial end and a caudal end, said plastic tube defining a main lumen for outflowing blood, a first balloon and a second balloon, spaced apart about said plastic tube and for inflation thereabout, said first balloon being contiguous to said cranial end;

wherein said balloons are sized and spaced on said plastic tube such that when inflated, they have sufficient size and spacing therebetween to isolate substantially all of the flow of toxified blood from said tumor and within said blood vessel;

fensetrations in said plastic tube between said balloons to said main lumen;

second and third lumina within said plastic tube;

said second lumen connecting to one of said first balloon and said second balloon; and

, said third lumen connecting to the other of said first balloon and said second balloon, for effecting inflation or deflation of said balloons;

said cranial end of said plastic tube being closed to substantially all inflow of blood; and

, a second catheter for returning blood removed through said main lumen to the patient, the imposement comprising;

structure for enabling said second balloon to slide along said plastic tube between a first position defining a minimum distance between said first balloon and said second balloon, and a second position defining a maximum distance between said first balloon and said second balloon, including a first stop positioned on the outer surface of said plastic tube within said second balloon for constraining the sliding distance of said second balloon to a position corresponding to a maximum distance between said first balloon and said second balloon and a second stop positioned on the outer surface of said plastic tube within said second balloon for constraining the sliding distance of said second balloon to a position corresponding to a minimum distance between said first balloon and said second balloon.

2. The apparatus of claim 1 wherein said cranial end is tapered to a diameter of an angiographic guide wire.

3. The apparatus of claim 2 wherein said plastic tube has a fourth lumen sized to accommodate an angiographic guide wire.

4. The apparatus of claim 1 wherein said second and third lumina connect and are common to the interiors of said balloons.

5. The apparatus of claim 1 wherein said second and third lumina lie within the wall of said plastic tube.

6. The apparatus of claim 1, wherein said second balloon further comprises a fluid tight seal position between said second balloon and said plastic tube.

7. A double balloon catheter comprising:

a first fixed balloon on the cranial end of said catheter;

a second slidable balloon positioned around said catheter and spaced from said first fixed balloon; and

,

structure for enabling said second balloon to slide along said plastic tube between a first position defining a minimum distance between said first balloon and said second balloon, and a second position defining a maximum distance between said first balloon and said second balloon, including a first stop positioned on the outer surface of said plastic tube within said second balloon for constraining the sliding distance of said second balloon to a position corresponding to a maximum distance between said first balloon and said second balloon and a second stop positioned on the outer surface of said plastic tube within said second balloon for constraining the sliding distance of said second balloon to a position corresponding to a minimum distance between said first balloon and said second balloon.

8. The apparatus of claim 7, wherein said second balloon further comprises a fluid tight seal position between said second balloon and said plastic tube.

9. The apparatus of claim 7, wherein said second balloon further comprises a fluid tight seal position between said second balloon and said plastic tube.

10. A method for the isolated infusion of chemotherapeutic agents into a tumor, comprising:

locating the blood vessel which receives substantially all blood which passes through said tumor;

determining the total length of said blood vessel which receives said substantially all blood;

providing a double balloon catheter which includes a first fixed balloon on the cranial end of said catheter;

a second slidable balloon positioned around said catheter and spaced from said first fixed balloon; and

, structure for enabling said second balloon to slide along said plastic tube between a first position defining a minimum distance between said first balloon and said second balloon, and a second position defining a maximum distance between said first balloon and said second balloon, including a first stop positioned on the outer surface of said plastic tube within said second balloon for constraining the sliding distance of said second balloon to a position corresponding to a maximum distance between said first balloon and said second balloon and a second stop positioned on the outer surface of said plastic tube within said second balloon for constraining the sliding distance of said second balloon to a position corresponding to a minimum distance between said first balloon and said second balloon;

sliding said second balloon to a position on said catheter sufficient to provide a distance between said first balloon and said second balloon larger that said total length;

inserting said catheter into said blood vessel to a point sufficient to isolate said total length from the remainder of the blood circulatory system of said patient;

infusing chemotherapeutic agents into said tumor, and;

extracorporeally withdrawing substantially all blood toxified by said chemotherapeutic agents from said tumor through said catheter from between said first balloon and said second balloon.