Disposable micropump

• US 5,919,167 A
• Filed: 04/08/1998
• Issued: 07/06/1999
• Est. Priority Date: 04/08/1998
• Status: Expired due to Term

• Current Assignee: Ferring Pharmaceuticals Incorporated (Ferring Holding SA)
• Original Assignee: Ferring Pharmaceuticals Incorporated (Ferring Holding SA)
• Inventors: VanRoyen, Donald F., Mulhauser, Paul J., Fontayne, Diego Y.
• Primary Examiner(s): Smith, Jeffrey A.
• Assistant Examiner(s): Robert, Eduardo C.
• Application Number:
  US09/056,751
• Time in Patent Office: 454 Days
• Field of Search: 604/131, 604/154, 604/155, 604/151
• US Class Current: 604/131
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 5/14546 Front-loading type injectors
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump

Abstract

An apparatus for delivery of a fluid is disclosed. The apparatus includes a syringe pump with a plunger, an electronic control element which releases at least one electric charge at predetermined time intervals, a shape memory element with a contractible length decreasing from an uncharged length to a charged length, and a driving mechanism connected to both the shape memory element and the plunger so that the change in length of the shape memory element causes the driving mechanism to provide an activating force to move the plunger and force the expulsion of the fluid from the syringe pump'"'"'s chamber. As the apparatus according to the present invention can be manufactured as a disposable unit, the problems associated with reusable syringe pumps are avoided.

Claims

1. An apparatus for delivery of a fluid comprising:

a syringe pump having a fluid-containing chamber, with an opening at a first end and a hole at a second end, and a plunger dimensioned for slidable engagement within the chamber such that when the plunger is acted upon by an activating force, the movement of the plunger from the opening towards the hole causes the fluid to be expelled from the chamber through the hole;

an electronic control element releasing at least one charge at predetermined time intervals;

a power source for providing electrical energy to the electronic control element;

a shape memory element connected to the electronic control element in such a manner to form an electric circuit, said shape memory element having a changeable length decreasing from a uncharged length to a charged length when the at least one charge is applied to the shape memory element and, under force of a return element, returning to the uncharged length when the at least one charge is removed; and

a driving mechanism connecting the shape memory element and the plunger such that the changeable length decreasing from the uncharged length to the charged length causes the driving mechanism to provide the activating force for movement of the plunger and expulsion of the fluid from the syringe pump chamber.

2. The apparatus of claim 1, wherein the chamber has an interior wall and the plunger has a top end connected to the driving mechanism, a bottom end configured such that when the bottom end contacts the second end of the chamber, substantially all fluid has been expelled from the chamber through the hole, and a side surface containing at least one seal member such that the plunger slidable engagement within the chamber involves contact only between the chamber interior wall and the at least one seal member.

3. The apparatus of claim 1, wherein the syringe pump chamber is made of an injection molded thermoplastic polymer and the shape memory element is made of a nickel-titanium alloy.

4. The apparatus of claim 1, wherein the power source is at least one battery and the electronic control element includes at least one capacitor for storing and releasing the at least one charge.

5. The apparatus of claim 1, wherein the electronic control element includes a time element for allowing the user to select a number of charges to be released and an interval at which the charges are released.

6. The apparatus of claim 1, further comprising a housing for retaining all components therein.

7. The apparatus of claim 6, wherein the housing includes a window to facilitate monitoring of the amount of fluid in the syringe pump.

8. The apparatus of claim 1, wherein the driving mechanism comprises:

a power screw attached to the plunger such that longitudinal movement of the power screw provides the activating force; and

a fixed nut through which the power screw is threaded such that rotation of the power screw through the nut results in the longitudinal movement of the power screw.

9. The apparatus of claim 8, wherein the driving mechanism further comprises a coupler for initiating the rotation of the power screw, the coupler having a bore for receiving the power screw configured and dimensioned such that the coupler and power screw rotate together.

10. The apparatus of claim 9, wherein the power screw has two threadless flat parallel surfaces and two threaded curved surfaces and the bore has two threadless flat parallel surfaces engaging the flat surfaces of the power screw.

11. The apparatus of claim 9, wherein the driving mechanism further comprises a pawl having a first end attached to the shape memory element and a second end contacting the coupler, the pawl moving from a resting position when the shape memory element has the uncharged length to an actuating position when the shape memory element has the charged length, said second end and coupler configured such that movement of the pawl causes the coupler to initiate the rotation of the power screw.

12. The apparatus of claim 11 wherein the return element comprises a return spring attached to the pawl to cause the pawl to return to the resting position.

13. The apparatus of claim 11, wherein the driving mechanism further comprises a limiting switch for stopping the at least one charge when the pawl moves past the actuating position and a projection on the first end of the pawl for engaging the limiting switch when the pawl moves past the actuating position.

14. The apparatus of claim 11, wherein the first end of the pawl has a channel to which the shape memory element is secured and the second end has an extension with a tab that engages a ratchet on an external surface of the coupler to initiate the rotation of the coupler.

15. The apparatus of claim 14, wherein a spring strip ratchet engages teeth of the ratchet to permit rotation of the coupler in one direction only.

16. The apparatus of claim 14, wherein the external surface of the coupler has a portion for manual rotation of the coupler.