Dry powder inhaler

• US 5,921,237 A
• Filed: 07/22/1996
• Issued: 07/13/1999
• Est. Priority Date: 04/24/1995
• Status: Expired due to Fees

• Current Assignee: Dura Pharmaceuticals, Inc. (Perrigo Company PLC)
• Original Assignee: Dura Pharmaceuticals, Inc. (Perrigo Company PLC)
• Inventors: Smith, Ian, Eisele, Robert F., Holton, Nelson, Kline, Tim, Davies, Karen
• Primary Examiner(s): Lewis, Aaron J.
• Application Number:
  US08/681,103
• Time in Patent Office: 1,086 Days
• Field of Search: 128/203.15, 128/203.21, 128/203.12
• US Class Current: 128/203.21
• CPC Class Codes: A61M 15/0006 using rotating means
• CPC Class Codes: A61M 15/0025 with caps
• CPC Class Codes: A61M 15/0031 by bursting or breaking the package, i.e. without cutting or piercing
• CPC Class Codes: A61M 15/0033 Details of the piercing or cutting means
• CPC Class Codes: A61M 15/0045 using multiple prepacked dosages on a same carrier, e.g. blisters
• CPC Class Codes: A61M 15/0048 the dosages being arranged in a plane, e.g. on diskettes
• CPC Class Codes: A61M 2016/0024 with an on-off output signal, e.g. from a switch
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2205/8206 battery-operated

Abstract

A drug powder inhaler has a cover plate pivotably attached to a lid on an inhaler housing. A lever is pivotably attached to the cover plate. A blister pack disk is rotatably mounted on the housing under the cover plate. A powder duct in the housing extends from a staging chamber underneath one end of the lever to an aerosolizing chamber. An actuator in the housing is pressed to shear open a blister on the blister pack disk and thereby deliver the drug dose contents of the blister into the staging chamber. A switch senses pressure in the mouthpiece and switches on a motor spinning an impeller within the aerosolizing chamber, when inhalation is detected.

Claims

1. An inhaler comprising:

a housing;

a cover plate pivotably attached to a lid on the housing;

a lever pivotably attached to the cover plate, the lever having an actuator end and a blister end;

a blister pack disk rotatably mounted on the housing, under the cover plate;

a powder duct in the housing under the blister end of the lever; and

an actuator extending through the housing and aligned with the actuator end of the lever.

2. The inhaler of claim 1 further comprising an enclosure attached to the cover plate.

3. The inhaler of claim 2 wherein the enclosure is pivotable with the cover plate on the housing from a first position wherein the enclosure covers the mouthpiece, to a second position wherein the mouthpiece is exposed.

4. The inhaler of claim 3 further comprising means for incrementally advancing the blister pack disk in one direction, with movement of the enclosure from the second position to the first position.

5. The inhaler of claim 2 further comprising an inside retainer and an outside retainer on the enclosure and slidably engageable to the housing.

6. The inhaler of claim 1 further comprising a removable mouthpiece on the housing.

7. The inhaler of claim 1 further comprising a ramp on the cover radially aligned with the actuator.

8. The inhaler of claim 7 further comprising a guidewall adjacent to the ramp.

9. The inhaler of claim 1 further comprising a hinge joint attaching the lid to the housing.

10. The inhaler of claim 1 further comprising a spring arm on the cover plate slidably engaged to a lifter on the lid.

11. The inhaler of claim 10 further comprising a tab at a free end of the spring arm adapted to engage a tab slot in the blister pack disk.

12. The inhaler of claim 1 further comprising racket posts on the housing underneath the blister pack disk.

13. The inhaler of claim 1 wherein the housing has a bottom and the actuator comprises a button on the bottom of the housing and post attached to the button and extending through the housing.

14. The inhaler of claim 13 further comprising a detent on the actuator.

15. The inhaler of claim 1 wherein the lid is transparent.

16. A method of powder inhalation by a patient comprising the steps of:

placing a disk having blisters containing a powder on an inhaler;

opening a blister and releasing powder from the blister into a staging chamber in the inhaler;

sensing inhalation by the patient;

spinning up an impeller in a mixing chamber in the inhaler in response to the sensed inhalation; and

drawing air and the powder from the staging chamber into the mixing chamber, after the impeller is already spinning.

17. The method of claim 16 further comprising the step of pivoting a lever to crush the blister.

18. A method of delivering a powder medicament for inhalation by a patient comprising the steps of:

providing a dry powder inhaler,

providing a plurality of blisters on a carrier on the dry powder inhaler;

pivoting a tab under the blister from a first tab position to a second tab position to shear the blister open;

pivoting a lever on the inhaler from a first lever position to a second lever position, to crush the blister;

moving the tab back to the first position; and

advancing the carrier to open a subsequent blister.

19. A dry powder inhaler comprising:

a housing having a top surface;

at least one rachet post on the top surface;

a cover attached to the housing;

an arm pivotably attached to the housing, the arm having a fixed end and a free end;

a tab extending from the free end of the arm toward the top surface of the housing; and

a lifter on the cover, for raising and lowering the free end of the arm as the arm pivots about the housing.