Container closure with a frangible seal and a connector for a fluid transfer device

• US 5,924,584 A
• Filed: 02/28/1997
• Issued: 07/20/1999
• Est. Priority Date: 02/28/1997
• Status: Expired due to Term

• Current Assignee: Hospira Incorporated (Pfizer Inc.)
• Original Assignee: Abbott Laboratories
• Inventors: Verlee, Donald, Moore, John K., Norman, John S., Hellstrom, Steven P., Tanner, John C. II, Karas, Peter J.
• Primary Examiner(s): Cronin, Stephen K.
• Application Number:
  US08/807,409
• Time in Patent Office: 872 Days
• Field of Search: 215/247, 215/249, 215/DIG. 3
• US Class Current: 215/247
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2055 having gripping means
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61J 2205/20 Colour codes
• CPC Class Codes: Y10S 215/03 Medical

Abstract

A closure is provided for mounting across the mouth of a container and through which liquid can be withdrawn with a fluid transfer device having a male member. The closure includes a body for being disposed on the container across the container mouth. The body defines a passage with an exterior opening for matingly receiving the male member of the fluid transfer device. A frangible seal initially extends across the passage in the body to occlude the passage. The seal is broken when it is engaged by the male member of the fluid transfer device, thereby establishing fluid communication between the fluid transfer device and the interior of the container.

Claims

1. A closure for mounting across the mouth of a container and through which fluid can be transferred using a fluid transfer device, said closure comprising:

a body to be disposed on said container across said container mouth to initially occlude said container mouth, said body defining a passage having an exterior opening to receive a fluid transfer device; and

a frangible seal initially extending across said passage to sealingly occlude said passage, said frangible seal including a generally flap-like transverse wall portion having a first peripheral section frangible connected to an adjacent region of said body and a second peripheral section defining a hinge connecting the transverse wall portion to the body, the frangible connection for the first peripheral portion constructed to be broken when engaged by a fluid transfer device to open the transverse wall portion about the hinge and establish fluid communication between the fluid transfer device and an interior of said container.

2. A closure in accordance with claim 1, wherein said body and said frangible seal are molded together as a unitary structure.

3. A closure in accordance with claim 1, wherein said frangible seal further includes an engaging protuberance projecting therefrom, said protuberance having a distal end to be engaged by a portion of a fluid transfer device.

4. A closure in accordance with claim 1, wherein said frangible seal has a stress concentrating element disposed to concentrate force applied by a fluid transfer device to initiate breakage of the frangible connection for the first peripheral section.

5. A closure in accordance with claim 1, wherein said closure further includes a peelable film sealingly secured to a portion of said body and extending over said passage exterior opening.

6. A closure in accordance with claim 1, wherein said closure further includes a lid and a hinge connecting said lid to said body, said lid constructed to cover said passage exterior opening in said body.

7. A closure in accordance with claim 1, wherein said closure further includes a metal ferrule having an annular deck constructed to retain a marginal portion of said body, said ferrule further having a skirt depending downwardly from said deck.

8. A closure in accordance with claim 1, wherein said body has a connector spout defining at least a portion of said passage.

9. A closure in accordance with claim 8, wherein the connector spout has a laterally projecting formation to engage a luer lock syringe.

10. A closure in accordance with claim 1, wherein the frangible connection for the first peripheral section includes a frangible connecting web of reduced thickness frangibly connecting the first peripheral section of said flap-like transverse wall portion to the adjacent region of said body, the second peripheral section of said flap-like transverse wall portion being permanently connected to said body to define the hinge.

11. A closure in accordance with claim 10, wherein the frangible seal is constructed of a material having a sufficient resiliency to effect return of said flap-like transverse wall portion substantially to its initial, unbroken orientation occluding said passage after removal of a fluid transfer device used to open the flap-like transverse wall portion.

12. A closure for a container, said closure comprising:

a body to be disposed across a mouth of the container, said body defining a passage therethrough, said passage having an exterior opening to receive a fluid transfer device; and

a frangible seal disposed across said passage of said body, said frangible seal fluidly sealing said passage, said frangible seal including a stress concentrator disposed on the frangible seal to concentrate force applied by a fluid transfer device received by said passage of said body and initiate breakage of the frangible seal.

13. A closure for a container in accordance with claim 12, wherein said frangible seal further includes a protuberance extending therefrom, and wherein said stress concentrator is disposed at a proximal end of said protuberance.

14. A closure in accordance with claim 12, wherein the frangible seal includes a generally flap-like transverse wall portion having a first peripheral section frangibly connected to an adjacent region of the body of the closure and a second peripheral section defining a hinge connecting the transverse wall portion to the body, the frangible connection for the first peripheral portion constructed to be broken initially by the stress concentrator when force is applied by a fluid transfer device to open the transverse wall portion about the hinge.

15. A container assembly for containing a product, the assembly comprising:

a container having a chamber defined therein, the container further defining a mouth in fluid communication with the chamber; and

a closure mounted across the container mouth through which a product can be transferred using a transfer device, the closure including

a body disposed across said container mouth, said body defining a passage having an exterior opening to receive a transfer device; and

a frangible seal initially extending across said passage to sealingly occlude said passage, said frangible seal including a generally flap-like transverse wall portion having a first peripheral section frangibly connected to an adjacent region of said body and a second peripheral section defining a hinge connecting the transverse wall portion to the body, the frangible connection for the first peripheral portion constructed to be broken by a transfer device to open the transverse wall portion about the hinge and establish fluid communication between the transfer device and the chamber of said container.

16. A container assembly in accordance with claim 15, wherein the container is selected from the group consisting of a bottle, a vial, a bag, and a tube set.

17. A container assembly in accordance with claim 15, wherein the frangible connection for the first peripheral section includes a frangible connecting web of reduced thickness frangibly connecting the first peripheral section of said flap-like transverse wall portion to the adjacent region of said body, the second peripheral section of said flap-like transverse wall portion being permanently connected to said body to define the hinge.

18. A container assembly in accordance with claim 15, wherein the frangible seal is constructed of a material having a sufficient resiliency to effect return of said flap-like transverse wall portion substantially to its initial, unbroken orientation occluding said passage after removal of a transfer device used to open the flap-like transverse wall portion.

19. A container assembly in accordance with claim 15, wherein said frangible seal further includes an engaging protuberance projecting therefrom, said protuberance having a distal end to be engaged by a transfer device.

20. A container assembly in accordance with claim 15, wherein said frangible seal has a stress concentrating element disposed to concentrate force applied by a transfer device to initiate breakage of the frangible connection for the first peripheral section.