Automatic capture detection during non-invasive programmed stimulation of a patient's heart

• US 5,925,067 A
• Filed: 12/11/1997
• Issued: 07/20/1999
• Est. Priority Date: 12/11/1997
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: Lu, Richard
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): LAYNO, CARL HERNANDZ
• Application Number:
  US08/988,582
• Time in Patent Office: 586 Days
• Field of Search: 607/17, 607/27, 607/28
• US Class Current: 607/28
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation

Abstract

A non-invasive programming stimulation system for performing electrophysiological testing on a cardiac patient is performed using a programmer coupled to an implantable device by a communication channel. The system generates stimulating pulses for the heart and analyzes the responses to determine the pathological condition of the heart. Advantageously, before analysis, the system automatically tests for capture by the stimulating pulses to insure that the pulses do not fall into an absolute refractory period.

Claims

1. A cardiac non-invasive programmed stimulation system for performing an electrophysiological test on a patient comprising:

a. an implantable device having

(i) a sense circuit for sensing electrical activity in said patient'"'"'s heart, said sense circuit generating a corresponding sense signal;

(ii) a pace generator for generating pulses for the heart in response to commands;

(iii) a controller for receiving said sense signals and for generating said commands in accordance with a program defined by programming information; and

(iv) an implant transceiver for receiving said programming information for said controller;

B. An external programmer having

(i) an input device for receiving instructions;

(ii) a controller for receiving said instructions and generating said programming information, said programming information defining for said implantable device a test mode of operation;

C. a test pulse generator for selectively generating test pulses for said heart while said implantable device is in said test mode, including a first set of test pulses and a second set of test pulses; and

;

D. a capture detector for automatically detecting when said test pulses of said second set of test pulses capture said heart

wherein said test pulse generator is coupled to said capture detector to adjust a characteristic of said second pulses when said capture detector does not detect capture by said second set of test pulses.

2. The system of claim 1 wherein said implantable device has an implantable housing and said capture detector is disposed in said implantable housing.

3. The system of claim 1 wherein said programmer has a programmer housing and said capture detector is disposed in said programmer housing.

4. The system of claim 1 wherein said implantable device has an implantable housing and said test pulse generator is disposed in said implantable housing.

5. The system of claim 1 wherein said programmer has a programmer housing and said test pulse generator is disposed in said programmer housing.

6. The system of claim 1 wherein said second set of pulses have a pulse interval and wherein said test generator changes said pulse interval when said capture detector indicates that some pulses of said second set did not result in capture.

7. The system of claim 1 wherein said test generator does not generate said second set of pulses if said capture detector indicates that said first set of pulses did not result in capture.

8. A NIPS system for evaluating the electrophysiological characteristics of a patient, said system comprising:

a test generator for generating selectively test pulses, including a first set of test pulses and a second set of test pulses;

electrodes coupled to said test generator and arranged to deliver said test pulses to the patient'"'"'s heart;

a sense circuit for sensing responses from said heart corresponding to said test pulses;

a capture detector coupled to said sense circuit to detect when said heart is captured by said test pulses; and

an evaluator for evaluating said responses once said capture is indicated by said capture detector,

wherein said test generator is adapted to generate said second set of pulses when said capture detector indicates that at least some pulses of said first set result in capture;

said test generator being further adapted to modify a characteristic of said second set of pulses if said capture detector indicates that at least some pulses of said second set do not result in capture.

9. The system of claim 8 further comprising a programmer and an implantable device.

10. The system of claim 9 wherein said programmer includes a programmer housing and said test generator is disposed in said programmer housing.

11. The system of claim 8 wherein said implantable device includes an implantable housing and said test generator is disposed in said implantable housing.

12. The system of claim 8 wherein said electrodes comprise implanted electrodes.

13. The system of claim 8 wherein said electrodes comprise surface electrodes.

14. The system of claim 8 further comprising an implantable device having a first and a second mode of operation, wherein said sense circuit is disposed in said implantable device and generates sense signals.

15. The system of claim 14 wherein said implantable device in said first mode operates independently to monitor said heart through said sense circuit, said implant further including an implantable housing and an implant pulse generator disposed in said implant housing and is responsive to said sense signals to generate therapeutic pulses.

16. The system of claim 15 wherein said test generator is disposed in said implantable housing and comprises said implant pulse generator.

17. A method of non-invasive programmed stimulation of a patient'"'"'s heart using a programmer and an associated implantable device in communication therewith, comprising the steps of:

generating a first train of pulses by one of said programmer and said implantable device;

testing if any pulses of said first train of pulses resulted in a capture of said heart;

terminating said testing if none of said pulses of said first train results in said capture; and

if said capture is present, evaluating the responses of the heart to said train of pulses.

18. The method of claim 17 further comprising:

generating a second train of second pulses if at least one of said first pulses results in capture;

testing if any of said second pulses result in capture; and

if at least some of the second pulses do not result in capture, then adjusting a characteristic of said second pulses.

19. The method of claim 18 further comprising adjusting an interval between said second pulses.

20. The method of claim 17 further comprising generating said train in said programmer.

21. The method of claim 17 further comprising generating said train in said implantable device.

22. A cardiac non-invasive programmed stimulation system for performing an electrophysiological test on a patient comprising:

a. an implantable device having

(i) a sense circuit for sensing electrical activity in said patient'"'"'s heart, said sense circuit generating a corresponding sense signal;

(ii) a pace generator for generating pulses for the heart in response to commands;

(iii) a controller for receiving said sense signals and for generating said commands in accordance with a program defined by programming information; and

(iv) an implant transceiver for receiving said programming information for said controller;

B. An external programmer having a programmer housing with;

(i) an input device for receiving instructions;

(ii) a controller for receiving said instructions and generating said programming information, said programming information defining for said implantable device a test mode of operation;

C. a test pulse generator for generating test pulses for said heart while said implantable device is in said test mode;

D. a capture detector for automatically detecting when said test pulses capture said heart, said capture detector being disposed in said programmer housing; and

E. a test evaluator for evaluating responses from said heart to said test pulses in the event of capture.

23. A cardiac non-invasive programmed stimulation system for performing an electrophysiological test on a patient comprising:

a. an implantable device having

(i) a sense circuit for sensing electrical activity in said patient'"'"'s heart, said sense circuit generating a corresponding sense signal;

(ii) a pace generator for generating pulses for the heart in response to commands;

(iii) a controller for receiving said sense signals and for generating said commands in accordance with a program defined by programming information; and

(iv) an implant transceiver for receiving said programming information for said controller;

B. An external programmer having a programmer housing with;

(i) an input device for receiving instructions;

(ii) a controller for receiving said instructions and generating said programming information, said programming information defining for said implantable device a test mode of operation;

C. a test pulse generator for generating test pulses for said heart while said implantable device is in said test mode, said test pulse generator being disposed in said programmer housing;

D. a capture detector for automatically detecting when said test pulses capture said heart; and

E. a test evaluator for evaluating responses from said heart to said test pulses in the event of capture.