Blooming, disinfectant concentrate compositions

• US 5,925,681 A
• Filed: 10/07/1997
• Issued: 07/20/1999
• Est. Priority Date: 03/01/1997
• Status: Expired due to Term

• Current Assignee: Reckitt Benckiser LLC (Reckitt Benckiser Group PLC)
• Original Assignee: Reckitt & Colman Inc. (Reckitt Benckiser Group PLC)
• Inventors: Smialowicz, Dennis Thomas, Crisanti, Michael George
• Primary Examiner(s): PAK, JOHN D
• Application Number:
  US08/944,992
• Time in Patent Office: 651 Days
• Field of Search: 514/642-643, 514/772, 514/722, 514/724, 514/739, 514/625, 514/627, 514/629, 514/937-943, 514/970, 514/973, 514/975, 422/28, 510/367, 510/382, 510/383, 510/384, 510/385, 510/391
• US Class Current: 514/643
• CPC Class Codes: A01N 25/04 Dispersions, emulsions, suspoemulsions, suspension concentrates or gels foams A01N25/16

Abstract

Concentrated aqueous liquid disinfectant compositions which exhibit a blooming effect when diluted in a larger volume of water are provided. The concentrate compositions include non-phenolic constituents to provide a disinfecting effect, and are non pine-oil containing. Working strength dilutions of the concentrated aqueous liquid disinfectant compositions are effective against gram positive type pathogenic bacteria such as Staphylococcus aureus, as well as gram negative type pathogenic bacteria such as Salmonella choleraesuis.

Claims

1. An aqueous liquid disinfectant concentrate composition which comprises:

(A) 0.1 to 50 wt. % of a volatile hydrophobic solvent;

(B) 0.1 to 50 wt. % of a hydrophilic solvent which stabilizes the volatile hydrophobic solvent;

(C) a nonionic alkoxylated fatty alcohol surfactant having a HLB value of between about 10 and about 15.

(D) 0.1 to 20 wt. % of a combination of (D1) a fatty alcohol ethoxylate or propxylate having 2-3 moles ethoxylation and/or propoxylation and an HLB value of between 7 and 9, with, (D2) an alkanolamide wherein the weight ratio of (D1);

(D2) is 10.0-1.0;

1.

(E) 0.1 to 20 wt. % of a non-phenolic compound which is effective in providing a germicidal effect;

(F) hydrotrope; and

,

(G) water.

2. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein:

the weight ratio of (D1);

(D2) is 3-5;

1.

3. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein:

the volatile hydrophobic solvent (A) is selected from the group consisting of mineral spirits, C₆ -C₁₂ alkanes, and C₆ -C₁₂ alkenes.

4. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein:

the hydrophilic solvent (B) is selected from the group consisting of lower alkyl alcohols, glycols, acetates, ether acetates and glycol ethers.

5. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein:

the hydrophilic solvent (B) is selected from the group consisting of;

methanol, ethanol, isopropanol, propylene glycol methyl ether, dipropylene glycol methyl ether, tripropylene glycol methyl ether, propylene glycol n-propyl ether, ethylene glycol n-butyl ether, diethylene glycol n-butyl ether, diethylene glycol methyl ether, propylene glycol, ethylene glycol, and ethylene glycol monobutyl ether acetate.

6. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein:

the hydrophilic solvent (B) exhibits a solubility in water of at least about 5 ml of the said hydrophilic solvent per 100 ml of water.

7. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the nonionic surfactant (C) is one or more condensation products of a long chain ethylene oxide moiety and/or long chain propylene oxide moeity with an aliphatic primary or secondary alcohol.

8. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the nonionic surfactant (C) is one or more condensation products of a long chain ethylene oxide moiety and/or long chain propylene oxide moeity with an alkyl phenol-based moiety wherein the alkyl chain is straight or branched and contains 6 to 12 carbon atoms.

9. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the nonionic surfactant (C) is one or more block copolymers according to one of the formulae:

(PO)_l (EO)_m (PO)_n

(EO)_l (PO)_m (EO)_n

where;

l, m and n are integer values selected so that the resulting block copolymer surfactant exhibits an HLB value of at least about 10;

EO represents an ethoxy group; and

,

PO represents a propoxy group.

10. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the fatty alcohol ethoxylate or propxylate having 2-3 moles ethoxylation and/or propoxylation and an HLB value of between 7 and 9 (D1) is one or more condensation products of a long chain ethylene oxide moiety and/or long chain propylene oxide moiety with an primary or secondary aliphatic alcohol containing 8 to 20 carbon atoms.

11. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the fatty alcohol ethoxylate or propxylate having 2-3 moles ethoxylation and/or propoxylation and an HLB value of between 7 and 9 (D1) is one or more condensation products of a long chain ethylene oxide moiety and/or long chain propylene oxide moiety with an alkyl phenol-based moiety wherein the alkyl chain is straight or branched and contains 6 to 12 carbon atoms.

12. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the (D2) alkanolamide is a C₈ -C₂₄ alkyl di(C₂ -C₃ alkanol) amides as represented by the formula:

##STR4## wherein R_c is a branched or straight chain C₈ -C₂₄ alkyl radical,

R_d and R_e are each a C₁ -C₄ alkyl radical.

13. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the (D2) alkanolamide is cocoamide diethanol amide or soyamide diethanolamide.

14. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the non-phenolic compound which is effective in providing a germicidal effect (E) is a quaternary ammonium germicide according to the structural formula:

##STR5## where at least one of R₁, R₂, R₃ and R₄ is a hydrophobic, aliphatic, aryl aliphatic or aliphatic aryl radical of from 6 to 26 carbon atoms and the remaining radical(s) R₁, R₂, R₃ and/or R₄ is/are substituent of hydrocarbon structure containing a total of no more than 12 carbons, and the entire cation portion of the molecule has a molecular weight of at least 165, and X may be any salt-forming anionic radical.

15. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the non-phenolic compound which is effective in providing a germicidal effect (E) is a quarternary ammonium compounds according to the structural formula:

##STR6## wherein R₂ and R₃ are the same or different C₈ -C₁₂ alkyl, or R₂ is C_12-16 alkyl, C_8-18 alkylethoxy, C_8-18 alkylphenolethoxy and R₃ is benzyl, and X is a halide or methosulfate.

16. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein the non-phenolic compound which is effective in providing a germicidal effect (E) is selected from the group consisting of:

blends of alkyl dimethyl benzyl ammonium chlorides, dialkyl(C₈ -C₁₀)dimethyl ammonium chloride, didecyl dimethyl ammonium chloride, dioctyl dimethyl ammonium chloride, alkyl dimethyl benzyl ammonium chloride, alkyl dimethyl benzyl ammonium chloride, alkyl dimethyl benzyl ammonium chloride and/or alkyl dimethyl ethyl benzyl ammonium chloride, myristyl dimethyl benzyl ammonium chloride, methyl dodecyl benzyl ammonium chloride and/or methyl dodecyl xylene-bix-trimethyl ammonium chloride, benzethonium chloride, alkyl dimethyl benzyl ammonium chloride, dialkyl methyl benzyl ammonium chloride and mixtures thereof.

17. The aqueous liquid disinfectant concentrate composition according to claim 1 wherein composition includes a constituent which improves the high temperature stability of the concentrate.

18. The aqueous liquid disinfectant concentrate composition according to claim 17 wherein said constituent which improves the high temperature stability of the concentrate is an amine, amine oxide, a nonionic surfactant which exhibits a cloud point in water at temperatures greater than 48°

C., or urea.

19. The aqueous liquid disinfectant concentrate composition according to claim 18 wherein the amine oxide is an alkyl di(lower alkyl) amine oxide in which the alkyl group has about 10-20 carbon atoms, which may be straight chained or branched chained, saturated or unsaturated, and where the lower alkyl groups include between 1 and 7 carbon atoms.

20. The aqueous liquid disinfectant concentrate composition according to claim 19 wherein said alkyl di(lower alkyl) amine oxide is selected from the group consisting of lauryl dimethyl amine oxide, myristyl dimethyl amine oxide, dimethyl cocoamine oxide, dimethyl (hydrogenated tallow) amine oxide, and myristyl/palmityl dimethyl amine oxide.

21. The aqueous liquid disinfectant concentrate composition according to claim 18 wherein the amine oxide is an alkyl di (hydroxy lower alkyl) amine oxide where the alkyl group has about 10-20 carbon atoms, which alkyl group may be straight chained or branched chained, and saturated or unsaturated.

22. The aqueous liquid disinfectant concentrate composition according to claim 21, wherein said alkyl di(hydroxy lower alkyl) amine oxide is selected from the group consisting of bis(2-hydroxyethyl) cocoamine oxide, bis(2-hydroxyethyl) tallowamine oxide, and bis(2-hydroxyethyl) stearylamine oxide.

23. The aqueous liquid disinfectant concentrate composition according to claim 18 wherein the constituent which improves the high temperature stability of the concentrate is urea.

24. An aqueous liquid disinfectant concentrate composition according to claim 1 which exhibits a blooming characteristic when dissolved in a greater volume of water.

25. The aqueous liquid disinfectant concentrate composition according to claim 1 which exhibits antimicrobial efficacy against one or more of the bacteria Staphylococcus aureus, Salmonella choleraesuis, and Pseudomonas aeruginosa.

26. A disinfecting composition comprising 1 part of the aqueous liquid disinfectant concentrate composition according to claim 1 diluted in at least one part of water which exhibits antimicrobial efficacy against one or more of the bacteria Staphylococcus aureus, Salmonella choleraesuis, and Pseudomonas aeruginosa.

27. A disinfecting composition comprising 1 part of the aqueous liquid disinfectant concentrate composition according to claim 1 diluted in at least 64 parts of water which exhibits antimicrobial efficacy against one or more of the bacteria Staphylococcus aureus, Salmonella choleraesuis, and Pseudomonas aeruginosa.

28. A disinfecting composition comprising 1 part of the aqueous liquid disinfectant concentrate composition according to claim 1 diluted in at least 64 parts of water which exhibits antimicrobial efficacy against at least two or more of the bacteria Staphylococcus aureus, Salmonella choleraesuis, and Pseudomonas aeruginosa.

29. A disinfecting composition comprising 1 part of the aqueous liquid disinfectant concentrate composition according to claim 1 diluted in at least 64 parts of water which exhibits antimicrobial efficacy against all three of the bacteria Staphylococcus aureus, Salmonella choleraesuis, and Pseudomonas aeruginosa.

30. A disinfecting composition comprising 1 part of the aqueous liquid disinfectant concentrate composition according to claim 1 diluted in 102 parts of water which exhibits antimicrobial efficacy against one or more of the bacteria Staphylococcus aureus, Salmonella choleraesuis, and Pseudomonas aeruginosa.

31. A disinfecting composition comprising 1 part of the aqueous liquid disinfectant concentrate composition according to claim 1 diluted in 102 parts of water which exhibits antimicrobial efficacy against at least two or more of the bacteria Staphylococcus aureus, Salmonella choleraesuis, and Pseudomonas aeruginosa.

32. An disinfecting composition comprising 1 part of the aqueous liquid disinfectant concentrate composition according to claim 1 diluted in 102 parts of water which exhibits antimicrobial efficacy against all three of the bacteria Staphylococcus aureus, Salmonella choleraesuis, and Pseudomonas aeruginosa.