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System for dispensing microvolume quantities of liquids

  • US 5,927,547 A
  • Filed: 06/12/1998
  • Issued: 07/27/1999
  • Est. Priority Date: 05/31/1996
  • Status: Expired due to Term
First Claim
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1. A microvolume liquid handling system for dispensing small quantities of liquids, comprising:

  • pump means for pumping a first liquid;

    microdispenser means for dispensing microvolumes of a second liquid, said first liquid and said second liquid separated by a compressible fluid, dispensing of said second liquid resulting in a pressure change of said first liquid and said second liquid;

    a pressure sensor for converting said pressure change in at least one of said first liquid and said second liquid into a signal;

    tubing means for connecting said pump means to said pressure sensor and said pressure sensor to said microdispenser means; and

    means for converting the signal into an indication of fluid volume dispensed.

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