Method and kit for determining the optimum dosage level of physiologically useful substances

• US 5,932,226 A
• Filed: 09/10/1996
• Issued: 08/03/1999
• Est. Priority Date: 10/03/1994
• Status: Expired due to Fees

• Current Assignee: Reckitt & Colman Overseas Ltd (Reckitt Benckiser Group PLC)
• Original Assignee: Harry M. Weiss
• Inventors: Ordman, Alfred B.
• Primary Examiner(s): Harrison, Robert H.
• Application Number:
  US08/709,258
• Time in Patent Office: 1,057 Days
• Field of Search: 424/400, 424/464, 514/161, 514/400, 514/464, 514/474
• US Class Current: 424/400
• CPC Class Codes: A61K 31/375 Ascorbic acid, i.e. vitamin C; Salts thereof
• CPC Class Codes: A61K 33/06 Aluminium, calcium or magnesium; Compounds thereof , e.g. clay
• CPC Class Codes: G01N 33/82 involving vitamins or their receptors

Abstract

A test kit and method for determining the optimal level of intake for an individual of a useful substance--including vitamin C and calcium--that is water soluble, urine excretable, and nontoxic at physiologically beneficial levels is disclosed.

Claims

1. In the oral administration of water-soluble, urine-excretable, nontoxic edible composition to a person, a method for producing a continuously-saturated level of at least one such water-soluble, urine excretable, nontoxic edible composition in the body of said person, comprising the following steps:

(a) administering a predetermined dose of said water-soluble, urine excretable, nontoxic edible composition to the person at a predetermined time;

(b) monitoring the concentration level of said water-soluble, urine excretable, nontoxic edible composition in the urine of said person to record any increase thereof during a 24 hour period following said predetermined time;

(c) increasing said predetermined dose by a predetermined amount and repeating steps (a) and (b) until a threshold dose is found that produces a sustained increase in said concentration level of said water-soluble, urine excretable, nontoxic edible composition in the urine of the person for a duration of time at least as long as a predetermined period; and

(d) administering no less than said threshold dose of said water-soluble, urine excretable, nontoxic edible composition to said person at intervals not larger than said duration of time.

2. The method of claim 1, wherein said composition is an anti-oxidant.

3. A method of administration of vitamin C to a person ensuring that a continuously-saturated level thereof is produced in the body of the person, comprising the step of taking more than 250 mg of vitamin C approximately every 12 hours to produce a continuously-saturated level of vitamin C in the body of the person over a 24 hour period.

4. The method of claim 3, wherein about 500 mg of vitamin C is taken approximately every 12 hours.

5. In the oral administration of calcium to a person, a method for producing a continuously-saturated level of calcium in the body of said person, comprising the following steps:

(a) administering a predetermined dose of calcium to said person at a predetermined time;

(b) monitoring the concentration level of calcium in the urine of said person to record any increase thereof during a 24 hour period following said predetermined time;

(c) increasing said predetermined dose by a predetermined amount and repeating steps (a) and (b) until a threshold dose is found that produces a sustained increase in said concentration level of calcium in the urine of said person for a duration of time at least as long as a predetermined period; and

(d) administering no less than said threshold dose of calcium to said person at intervals not larger than said duration of time.