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Multiarmed, monofunctional, polymer for coupling to molecules and surfaces

  • US 5,932,462 A
  • Filed: 05/17/1995
  • Issued: 08/03/1999
  • Est. Priority Date: 01/10/1995
  • Status: Expired due to Term
First Claim
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1. An essentially pure water soluble polymer having a moiety located along the polymer backbone, which moiety comprises a single ionizable reactive group, wherein said polymer is represented by the structure:

  • ##STR30## wherein C is carbon;

    wherein R is a nonreactive moiety;

    wherein Z is said moiety comprising a single ionizable reactive group;

    wherein polya and polyb are nonpeptidic and nonreactive polymeric arms that may be the game or different;

    wherein P and Q are nonreactive linkage fragments that may be the same or different and join polymeric arms polya and polyb, respectively, to C in the absence of aromatic rings and ester groups in said fragments, and wherein said polymer is recovered in essentially pure form by ion exchange chromatography.

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