Microfluidic analyzer module
First Claim
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1. A microfluidic analyzer module comprising:
- (a) a first sheet of an adhesiveless self-bondable polyimide having a top surface and a bottom surface;
(b) a second sheet of an adhesiveless self-bondable polyimide having a top surface and a bottom surface, said first and second polyimide sheets being in superposed relation with said bottom surface of said first sheet of polyimide facing said top surface of said second sheet of polyimide, said sheets being directly bonded together at the interface of the sheets without an adhesive; and
(c) at least one fluid flow channel at the interface of said first sheet and said second sheet.
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Abstract
A microfluidic analyzer module. The module is constructed of a plurality of channel forming laminate layers that are directly bonded together without adhesive or other possible contaminant source located proximate the flow channels. The channel forming laminate layers define a network of fluid flow channels. A valve containing layer is directly, adhesivelessly bonded over the channel containing layers. A flexible valve member integral with the valve layer opens and closes communication between feed and sensor channels of the channel network.
636 Citations
16 Claims
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1. A microfluidic analyzer module comprising:
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(a) a first sheet of an adhesiveless self-bondable polyimide having a top surface and a bottom surface; (b) a second sheet of an adhesiveless self-bondable polyimide having a top surface and a bottom surface, said first and second polyimide sheets being in superposed relation with said bottom surface of said first sheet of polyimide facing said top surface of said second sheet of polyimide, said sheets being directly bonded together at the interface of the sheets without an adhesive; and (c) at least one fluid flow channel at the interface of said first sheet and said second sheet. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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- 8. A laminated microfluidic analyzer module comprising first, second and third layers of polymeric materials, said first and second layers being interfacing layers of adhesiveless self-bondable polyimide polymer which are directly bonded together without adhesive to form a structure having a top surface and a bottom surface, said structure having a fluid flow channel formed at the interface of said layers, said fluid flow channel being in communication with said top surface of said structure, a portion of said top surface being in operative association with said fluid flow channel and constituting a valve region, said third layer of polymeric material superposed over said top surface of said structure overlying said valve region, the portion of said third polymeric material overlying said valve region constituting a valve, said third layer of polymeric material being flexible and being bonded over said top surface of said structure except at said valve region, said third layer of polymeric material retaining its flexibility at said valve region, and a valve actuator operatively associated with said third layer of polymeric material at said valve region for selectively flexing said third layer and thereby closing and opening said valve.
Specification