Method and system for detecting material using piezoelectric resonators

• US 5,932,953 A
• Filed: 06/30/1997
• Issued: 08/03/1999
• Est. Priority Date: 06/30/1997
• Status: Expired due to Term

• Current Assignee: Iowa State University Research Foundation Incorporated (Iowa State University)
• Original Assignee: Iowa State University Research Foundation Incorporated (Iowa State University)
• Inventors: Van Deusen, Richard A., Drees, Dennis M., Shanks, Howard R., Landin, Allen R.
• Primary Examiner(s): BUDD, MARK OSBORNE
• Application Number:
  US08/884,991
• Time in Patent Office: 764 Days
• Field of Search: 310/312, 310/316, 310/319, 310/321, 310/324, 310/334, 73/23.2, 73/23.4, 73/23.28, 73/24.01, 73/24.05, 73/24.06, 73/25.05, 73/30.01, 73/30.03, 73/30.04, 73/31.05, 73/31.06, 73/54.41
• US Class Current: 310/324
• CPC Class Codes: G01N 2291/012 Phase angle
• CPC Class Codes: G01N 2291/0231 Composite or layered materials
• CPC Class Codes: G01N 2291/0256 Adsorption, desorption, surface mass change, e.g. on biosensors
• CPC Class Codes: G01N 2291/0421 Longitudinal waves
• CPC Class Codes: G01N 2291/0422 Shear waves, transverse waves, horizontally polarised waves
• CPC Class Codes: G01N 29/022 Fluid sensors based on microsensors, e.g. quartz crystal-microbalance [QCM], surface acoustic wave [SAW] devices, tuning forks, cantilevers, flexural plate wave [FPW] devices microdevices per se B81B

Abstract

A method and system for detecting material bound on a surface of a piezoelectric resonator introduces a signal of a constant frequency through the sensing resonator and detects a change in the insertion phase shift of the resonator as a result of the binding of the material being detected on the surface of the resonator. Environmental effects on the measurement are effectively canceled by the use of a reference resonator driven by the same input signal. A multiple-port sensing device is provided which includes thin-film sensing and reference resonators monolithically formed on a substrate.

Claims

1. A method of detecting binding of material on a surface of a piezoelectric resonator operable in a bulk-acoustic wave resonant mode, comprising the steps of:

coupling an input electrical signal to the piezoelectric resonator, the input electric signal having a frequency within a resonance band of the piezoelectric resonator;

transmitting the input electrical signal through the piezoelectric resonator to generate an output electrical signal having a frequency identical to the frequency of the input electrical signal;

receiving the output electrical signal from the piezoelectric resonator; and

determining a change in insertion phase shift of the output electrical signal caused by binding of the material on the surface of the piezoelectric resonator, whereby the change in insertion phase shift provides quantitative information regarding the binding of the material on the surface of the piezoelectric resonator.

2. A method as in claim 1, wherein the step of determining includes deriving a rate of change of the insertion phase shift, said rate of change indicative of a concentration of the material being detected.

3. A method as in claim 1, wherein the piezoelectric resonator is a thin-film resonator.

4. A method as in claim 3, wherein the thin-film resonator is formed of AlN.

5. A method as in claim 3, wherein the thin-film resonator is formed of ZnO.

6. A method as in claim 1, wherein the step of coupling transmits the input electrical signal to an electrode of the piezoelectric resonator, and wherein the step of receiving receives the output electrical signal from said electrode.

7. A method as in claim 1, wherein the step of transmitting transmits the input electrical signal to a first electrode of the piezoelectric resonator, and wherein the step of receiving receives the output electrical signal from a second electrode of the piezoelectric resonator.

8. A method as in claim 1, wherein the bulk-acoustic wave resonant mode is a shear mode.

9. A method as in claim 1, wherein the bulk-acoustic wave resonant mode is a longitudinal mode.

10. A method as in claim 1, wherein the step of determining includes mixing the output electrical signal with a reference signal and providing a DC signal proportional to a phase difference between the output electrical signal and the reference signal.

11. An apparatus for detecting material comprising:

a piezoelectric resonator operable in a bulk-acoustic wave resonant mode and having a surface for binding with the material being detected;

a signal source for generating an input electrical signal having a frequency within a resonance band of the piezoelectric resonator, the signal source coupled to the piezoelectric resonator for transmitting the input electrical signal through the piezoelectric resonator to generate an output electrical signal having a frequency identical to the frequency of the input electrical signal;

a phase detector coupled to the piezoelectric resonator for receiving therefrom the output electrical signal and generating a phase signal indicative of a change in insertion phase shift of the piezoelectric resonator caused by binding of the material on the surface of the piezoelectric resonator.

12. An apparatus as in claim 11, wherein the piezoelectric resonator is a thin film resonator.

13. An apparatus as in claim 12, wherein the thin film resonator is formed of AlN.

14. An apparatus as in claim 12, wherein the thin-film resonator is formed of ZnO.

15. An apparatus as in claim 11, wherein the phase signal generated by the phase detector is a DC voltage indicative of the change in insertion phase shift.

16. An apparatus as in claim 11, wherein the bulk-acoustic wave resonant mode of the piezoelectric resonator is a shear mode.

17. An apparatus as in claim 11, wherein the bulk-acoustic wave resonant mode of the piezoelectric resonator is a longitudinal mode.

18. An apparatus for material detection comprising:

a reference resonator and at least one sensing resonator supported for bulk-acoustic wave resonance, the reference resonator having a resonant band overlapping a resonant band of the sensing resonator, the sensing resonator having a surface for binding with the material being detected;

a signal source providing an input signal having a frequency within an overlapping portion of the resonance bands of the reference resonator and the sensing resonator, the signal generator coupled to the reference resonator and the sensing resonator for transmitting the input signal therethrough to generate respectively a reference signal and a sensor signal each having a frequency identical to the frequency of the input signal;

a phase detector coupled to the reference resonator and the sensing resonator to receive the reference signal and the sensor signal, the phase detector generating a phase signal representing a phase difference between the reference signal and the sensor signal, whereby the phase difference is altered by binding of the material on the surface of the sensing resonator.

19. An apparatus as in claim 18, wherein said reference resonator and at least one sensing resonator are thin film resonators monolithically formed on the substrate.

20. An apparatus as in claim 19, wherein the thin-film resonators are formed of AlN.

21. An apparatus as in claim 19, wherein the thin-film resonators are formed of ZnO.

22. An apparatus as in claim 18, wherein the reference resonator and the sensing resonator each has an input electrode coupled to the signal source for receiving the input signal and an output electrode connected to the phase detector to provide respectively the reference signal and the sensor signal.

23. An apparatus as in claim 18, wherein the input electrodes of the sensing resonator and the reference resonator are connected to a transmission line formed on the substrate for coupling the input signal to the respective resonators.

24. An apparatus as in claim 18, wherein each of the reference resonator and the sensing resonator operates in a longitudinal mode.

25. An apparatus as in claim 18, wherein each of the reference resonator and the sensing resonator operates in a shear mode.

26. A method of detecting material comprising the steps of:

providing a sensing resonator and a reference resonator supported for bulk-acoustic wave resonance, the sensing resonator having a resonant band overlapping a resonant band of the reference resonator, the sensing resonator having a surface for binding with the material being detected; and

generating an input signal within an overlapping portion of the resonant bands of the reference resonator and the sensing resonator;

coupling the input signal to the reference resonator and the sensing resonator and transmitting the input signal therethrough to generate respectively a reference signal and a sensor signal each having a frequency identical to the frequency of the input signal;

detecting a change in phase difference between the sensor signal and the reference signal in response to the binding of the material on the surface of the sensing resonator.

27. A method as in claim 26, wherein the step of detecting includes deriving a rate of change in phase difference between the sensor and reference signals.

28. A method as in claim 26, wherein the reference resonator and the sensing resonator are thin film resonators monolithically formed on a substrate.

29. A method as in claim 28, wherein the step of coupling couples the input signal to the reference resonator and the sensing resonator through a power divider formed on the substrate.

30. A method as in claim 26, wherein each of the reference resonator and the sensing resonator operates in a shear mode.

31. A method as in claim 26, wherein each of the reference resonator and the sensing resonator operates in a longitudinal mode.

32. A monolithic sensor for detecting adsorption of material comprising:

a substrate layer;

a reference resonator and at least one sensing resonator formed on the substrate layer and supported for bulk-acoustic wave resonance, each of the reference resonator and the sensing resonator having a thin-film piezoelectric layer and input and output electrodes on opposite sides of the piezoelectric layer, the reference resonator having a resonance band overlapping a resonance band of the sensing resonator;

a first transmission line formed on the substrate layer for coupling an input electrical signal;

a power divider connected to the first transmission line and the input electrodes of the reference resonator and the sensing resonator for directing the input electrical signal from the first transmission line to the reference and sensing resonators;

a second transmission line formed on the substrate layer and connected to the output electrode of the reference resonator for delivering a reference signal generated by transmitting the input electrical signal through the reference resonator and having a frequency identical to the frequency of the input electrical signal; and

a third transmission line formed on the substrate layer and connected to the output electrode of the sensing resonator for delivering a sensor signal generated by transmitting the input electrical signal through the sensing resonator and having a frequency identical to the frequency of the input electrical signal.

33. A monolithic sensor as in claim 32, wherein the thin-film piezoelectric layers of the reference resonator and the sensing resonator are formed of AlN.

34. A monolithic sensor as in claim 32, wherein the thin-film piezoelectric layers of the reference resonator and the sensing resonator are formed of ZnO.

35. A monolithic sensor as in claim 32, wherein each of the reference resonator and the sensing resonator operates in a shear mode.

36. A monolithic sensor as in claim 32, wherein each of the reference resonator and the sensing resonator operates in a longitudinal mode.

37. A monolithic sensor as in claim 32, wherein the power divider is a T-junction.