Visual prosthesis and method of using same

• US 5,935,155 A
• Filed: 03/13/1998
• Issued: 08/10/1999
• Est. Priority Date: 03/13/1998
• Status: Expired due to Term

• Current Assignee: Johns Hopkins University
• Original Assignee: Johns Hopkins University
• Inventors: Greenberg, Robert J., Humayun, Mark S., de Juan, Eugene Jr.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US09/041,933
• Time in Patent Office: 515 Days
• Field of Search: 607/53, 607/54, 607/116
• US Class Current: 607/54
• CPC Class Codes: A61M 2039/1033 Swivel nut connectors, e.g. threaded connectors, bayonet-connectors
• CPC Class Codes: A61M 39/10 Tube connectors; Tube couplings A61M39/02 takes precedence; connecting needles to syringes or hubs A61M5/34; connecting catheter tubes to hubs A61M25/0014
• CPC Class Codes: A61M 39/1011 Locking means for securing connection; Additional tamper safeties A61M39/16 takes precedence
• CPC Class Codes: A61M 5/3213 Caps placed axially onto the needle, e.g. equipped with finger protection guards axially-extensible protective sleeves A61M5/3243
• CPC Class Codes: A61N 1/0543 Retinal electrodes
• CPC Class Codes: A61N 1/36046 of the eye

Abstract

A visual prosthesis comprises a camera for perceiving a visual image and generating a visual signal output, retinal tissue stimulation circuitry adapted to be operatively attached to the user'"'"'s retina, and wireless communication circuitry for transmitting the visual signal output to the retinal tissue stimulation circuitry within the eye. To generate the visual signal output the camera converts a visual image to electrical impulses which are sampled to selecting an image at a given point in time. The sampled image signal is then encoded to allow a pixelized display of it. This signal then is used to modulate a radio frequency carrier signal. A tuned coil pair having a primary and a secondary coil are used to transmit and receive the RF modulated visual signal which is then demodulated within the eye. The retinal stimulation circuitry includes a decoder for decoding the visual signal output into a plurality of individual stimulation control signals which are used by current generation circuitry to generate stimulation current signals to be used by an electrode array having a plurality of electrodes forming a matrix. The intraocular components are powered from energy extracted from the transmitted visual signal. The electrode array is attached to the retina via tacks, magnets, or adhesive.

Claims

1. A visual prosthesis, comprising:

means for perceiving a visual image, said means producing a visual signal output in response thereto;

retinal tissue stimulation means adapted to be operatively attached to a retina of a user; and

wireless visual signal communication means for transmitting said visual signal output to said retinal tissue stimulation means.

2. The visual prosthesis of claim 1, wherein said means for perceiving a visual image comprises:

camera means for converting a visual image to electrical impulses;

image sampling means coupled to said camera means for selecting an image at a given point in time; and

encoder means coupled to said image sampling means for encoding said selected image to allow a pixelized display thereof.

3. The visual prosthesis of claim 1, wherein said retinal tissue stimulation means comprises:

decoder means responsive to said visual signal output for decoding said visual signal output into a plurality of individual stimulation control signals;

current generation circuitry means coupled to said decoder means and responsive to said plurality of individual stimulation control signals for generating stimulation current signals; and

an electrode array having a plurality of electrodes operatively coupled to said current generation circuitry means, said electrodes being responsive to said individual stimulation control signals to generate stimulation pulses sufficient to stimulate retinal tissue.

4. The visual prosthesis of claim 3, said electrode array further comprising attachment means adapted for attaching said electrode array to the retina of a user.

5. The visual prosthesis of claim 4, wherein said electrode array defines at least one mounting aperture therein, and wherein said attachment means comprises at least one retinal tack positioned within said at least one mounting aperture.

6. The visual prosthesis of claim 4, wherein said electrode array includes an outer surface edge defining at least two scalloped portions therein, and wherein said attachment means comprises a retinal tack positioned within each of said scalloped portions.

7. The visual prosthesis of claim 4, wherein said electrode array includes at least a first magnet attached thereto, and wherein said attachment means comprises a second magnet adapted to be attached on the outside of the sclera of a user opposite a desired point of attachment of said electrode array on the retina.

8. The visual prosthesis of claim 4, wherein said attachment means comprises adhesive placed on a surface of said electrode array to be attached to the retina.

9. The visual prosthesis of claim 1, wherein said wireless visual signal communication means comprises:

a carrier generator means for generating a radio frequency carrier signal;

modulator means responsive to said radio frequency carrier signal and to said visual signal output for modulating said radio frequency carrier signal by said visual signal output, said modulator means producing a radio frequency modulated image signal;

a tuned coil pair having a primary and a secondary coil, said primary coil operatively coupled to said modulator means to transmit said radio frequency modulated image signal, said secondary coil being tuned to receive said radio frequency modulated image signal; and

demodulator means coupled to said secondary coil for extracting said visual signal output from said radio frequency carrier signal.

10. The visual prosthesis of claim 9, further comprising power supply means coupled to said secondary coil for powering said retinal tissue stimulation means and said demodulator means by extracting energy from said radio frequency modulated image signal.

11. The visual prosthesis of claim 10, wherein said power supply means rectifies said radio frequency carrier signal from said radio frequency modulated image signal received by said secondary coil to produce a dc power output to power said retinal tissue stimulation means and said demodulator means.

12. A medical device to at least partially restore vision in users who suffer from photoreceptor degenerative conditions, comprising:

camera means for converting a visual image to electrical impulses;

image sampling means coupled to said camera means for selecting an image at a given point in time;

encoder means coupled to said image sampling means for encoding said selected image to allow a pixelized display thereof, said encoder means outputting a visual signal output;

a carrier generator means for generating a radio frequency carrier signal;

modulator means responsive to said radio frequency carrier signal and to said visual signal output for modulating said radio frequency carrier signal by said visual signal output, said modulator means producing a radio frequency modulated image signal;

a tuned coil pair having a primary and a secondary coil, said primary coil operatively coupled to said modulator means to transmit said radio frequency modulated image signal, said secondary coil being tuned to receive said radio frequency modulated image signal;

demodulator means coupled to said secondary coil for extracting said visual signal output from said radio frequency carrier signal;

decoder means coupled to said demodulator means and responsive to said visual signal output for decoding said visual signal output into a plurality of individual stimulation control signals;

current generation circuitry means coupled to said decoder means and responsive to said plurality of individual stimulation control signals for generating stimulation current signals; and

an electrode array having a plurality of electrodes operatively coupled to said current generation circuitry means, said electrodes being responsive to said individual stimulation control signals to generate stimulation pulses sufficient to stimulate retinal tissue to generate phosphenes.

13. The medical device of claim 12, further comprising power supply means coupled to said secondary coil for powering said demodulator means, said decoder means, and said current generation circuitry means by extracting energy from said radio frequency modulated image signal.

14. The medical device of claim 13, wherein said electrode array is adapted for intraocular implantation.

15. The medical device of claim 14, wherein said secondary coil is adapted for intraocular implantation.

16. The medical device of claim 15, wherein said demodulator means, said decoder means, said current generation circuitry means, and said power supply means are adapted for intraocular implantation.

17. The medical device of claim 14, further comprising attachment means adapted for attaching said electrode array to retinal tissue of the user.

18. The medical device of claim 17, wherein said electrode array defines at least one mounting aperture therein, and wherein said attachment means comprises at least one retinal tack positioned within said at least one mounting aperture.

19. The medical device of claim 17, wherein said electrode array includes an outer surface edge defining at least two scalloped portions therein, and wherein said attachment means comprises a retinal tack positioned within each of said scalloped portions.

20. The medical device of claim 17, wherein said electrode array includes at least a first magnet attached thereto, and wherein said attachment means comprises a second magnet adapted to be attached on the outside of the sclera of a user opposite a desired point of attachment of said electrode array on the retina.

21. The medical device of claim 17, wherein said attachment means comprises adhesive placed on a surface of said electrode array to be attached to the retina.

22. A method of at least partially restoring vision to users who suffer from photoreceptor degenerative retinal conditions of the eye, comprising the steps of:

perceiving a visual image and producing a visual signal output in response thereto;

wirelessly transmitting the visual signal output into the eye;

stimulating retinal tissue of the user in accordance with the visual signal output.

23. The method of claim 22, wherein said step of perceiving a visual image and producing a visual signal output in response thereto comprises the steps of:

converting a visual image to electrical impulses;

sampling the electrical impulses corresponding to an image at a given point in time; and

encoding said selected image to allow a pixelized display thereof.

24. The method of claim 22, wherein said step of wirelessly transmitting the visual signal output into the eye comprises the steps of:

generating a radio frequency carrier signal;

modulating said radio frequency carrier signal by said visual signal output to produce a radio frequency modulated image signal;

transmitting said radio frequency modulated image signal;

receiving said radio frequency modulated image signal; and

extracting said visual signal output from said radio frequency carrier signal.

25. The method of claim 22, wherein said step of stimulating retinal tissue of the user in accordance with the visual signal output comprises the steps of:

decoding said visual signal output into a plurality of individual stimulation control signals;

generating stimulation current signals; and

applying stimulation to the retinal tissue in accordance with the stimulation current signals.