Surface modified electrophoretic chambers
First Claim
1. An electrophoretic chamber comprising at least a region of surface modification, wherein said region comprises:
- a rigid polymeric base material;
an anchoring polymeric layer interpenetrating the surface of said base material; and
a polymeric electrophoretic layer copolymerized to said anchoring polymeric layer.
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Accused Products
Abstract
Electrophoretic chambers comprising at least a region of surface modification, and methods for their fabrication, are provided. The subject chambers comprise in the region of surface modification, an anchoring polymeric layer interpenetrating the surface of the chamber and an electrophoretic polymeric layer copolymerized with the anchoring polymeric layer. The subject chambers are prepared by sequentially contacting the chamber surface with a first monomer capable of interpenetrating the surface and a second monomer capable of copolymerization with the first monomer, followed by copolymerization of the first and second monomers. The subject devices find use a variety of electrophoretic applications in which entities are moved through a medium under the influence of an applied electric field.
191 Citations
37 Claims
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1. An electrophoretic chamber comprising at least a region of surface modification, wherein said region comprises:
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a rigid polymeric base material; an anchoring polymeric layer interpenetrating the surface of said base material; and a polymeric electrophoretic layer copolymerized to said anchoring polymeric layer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. An electrophoretic chamber comprising at least one region of surface modification, wherein said region comprises:
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a rigid acrylic material; an anchoring acrylic polymeric layer interpenetrating the surface of said rigid acrylic material; and a polymeric electrophoretic layer copolymerized with said anchoring polymeric layer, wherein at least one of said anchoring and electrophoretic layers differs from said rigid acrylic material. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 22, 23)
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20. A device comprising an electrophoretic chamber comprising at least a region of surface modification, wherein said region comprises:
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a rigid polymeric base material; an anchoring polymeric layer interpenetrating the surface of said base material; and a polymeric electrophoretic layer copolymerized to said anchoring polymeric layer. - View Dependent Claims (21, 32, 33, 34)
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24. A method for making a polymeric electrophoretic chamber comprising at least one region of surface modification, said method comprising:
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contacting the surface of a rigid polymeric base material in said region with a first monomer capable of interpenetrating said surface to produce an interpenetrated surface; contacting said interpenetrated surface with a second monomer capable of copolymerizing with said first monomer; and copolymerizing said first and second monomers to produce said electrophoretic chamber. - View Dependent Claims (25, 26, 27)
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28. A method for making a polymeric electrophoretic chamber comprising at least one region of surface modification, said method comprising:
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contacting the surface of a polymethylmethacrylate base material in said region with a first acrylic monomer capable of interpenetrating said surface to produce an interpenetrated surface; contacting said interpenetrated surface with a second monomer capable of copolymerizing with said first monomer; and copolymerizing said first and second monomers to produce said electrophoretic chamber. - View Dependent Claims (29, 30, 31)
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35. A device comprising:
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a rigid polymeric material having a first surface comprising at least one microchannel; a first polymeric layer interpenetrating said first surface; and a second polymeric material copolymerized with said first polymeric layer. - View Dependent Claims (36, 37)
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Specification