Antiviral therapy using ovine or bovine interferon-tau
First Claim
1. A method of inhibiting viral replication in cells of a subject infected with a virus, comprisingadministering ovine or bovine interferon-tau to the subject in an amount effective to inhibit viral replication within said cells and which induces a chance in white blood cell count in the subject which is less than the change in white blood cell count which would be induced in the subject by an amount of interferon-alpha having the same viral inhibition effect.
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Abstract
The invention provides antiviral therapeutic methods employing bovine or ovine interferon-tau (IFN-τ) proteins and polypeptides. The IFN-τ proteins exhibit the antiviral and antiproliferative properties characteristic of type I interferons. An advantage of the invention is that IFN-τ has essentially no cytotoxic effects on treated cells as does, for example, IFN-α.
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8 Claims
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1. A method of inhibiting viral replication in cells of a subject infected with a virus, comprising
administering ovine or bovine interferon-tau to the subject in an amount effective to inhibit viral replication within said cells and which induces a chance in white blood cell count in the subject which is less than the change in white blood cell count which would be induced in the subject by an amount of interferon-alpha having the same viral inhibition effect.
Specification