Quinazoline derivatives
First Claim
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1. A quinazoline derivative of the formula I ##STR4## wherein n is 1, 2 or 3 and each R2 is independently halogeno;
- and R1 is (1-4C)alkoxy-(2-4C)alkylamino;
or a pharmaceutically-acceptable salt thereof.
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Abstract
The invention concerns quinazoline derivatives of formula wherein n is 1, 2 or 3 and each R2 is independently halogeno; and R1 is 1-4C)alkoxy-(2-4C)alkylamino; or pharmaceutically-acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them, and the use of the receptor tyrosine kinase inhibitory properties of the compounds in the treatment of proliferative disease such as cancer.
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Citations
9 Claims
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1. A quinazoline derivative of the formula I ##STR4## wherein n is 1, 2 or 3 and each R2 is independently halogeno;
- and R1 is (1-4C)alkoxy-(2-4C)alkylamino;
or a pharmaceutically-acceptable salt thereof. - View Dependent Claims (2, 7, 8, 9)
- and R1 is (1-4C)alkoxy-(2-4C)alkylamino;
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3. A quinazoline derivative of the formula I ##STR5## wherein (R2)n is 3'"'"',4'"'"'-difluoro or 3'"'"'-chloro-4'"'"'-fluoro;
- and R1 is 2-methoxyethylamino or 3-methoxypropylamino;
or a pharmaceutically-acceptable acid-addition salt thereof. - View Dependent Claims (4, 5, 6)
- and R1 is 2-methoxyethylamino or 3-methoxypropylamino;
Specification