Potential and diffusion controlled solid electrolyte sensor for continuous measurement of very low levels of transdermal alcohol
First Claim
1. A transdermal alcohol sensing instrument comprising:
- a sensor cell for measuring ethanol vapor at the surface of the skin of a person being monitored;
a potential control circuit for controlling the operation of said sensor cell;
at least one diffusion-control membrane mounted over the sensor cell on the side of said sensor cell designed to contact the skin of the person being measured, said diffusion-control membrane having a lower ethanol permeability than the human stratum corneum, said diffusion-control membrane controlling ethanol and water vapor flux from the skin to the sensor cell.
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Abstract
A method for continuous tracking of blood alcohol, is comprised of 1) a potential- and diffusion-controlled electrochemical solid polymer electrolyte sensor that continuously and concurrently measures very low concentrations of ethanol vapor at the surface of the skin as well as skin properties such as temperature and ionic conductivity, 2) a sensor control circuit, and 3) a data acquisition-recording device. Sensitive and reproducible measurements of ethanol over a wide population range is obtained by simultaneously maintaining the potential of the sensing electrode constant at a voltage above the rest potential of the platinum/air (O2) electrode and by use of a thin, permselective diffusion-control membrane over the sensing electrode, and in series with the human stratum corneum membrane. The electrochemical oxidation current is a direct measure of the local ethanol vapor concentration over the skin surface.
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Citations
13 Claims
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1. A transdermal alcohol sensing instrument comprising:
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a sensor cell for measuring ethanol vapor at the surface of the skin of a person being monitored; a potential control circuit for controlling the operation of said sensor cell; at least one diffusion-control membrane mounted over the sensor cell on the side of said sensor cell designed to contact the skin of the person being measured, said diffusion-control membrane having a lower ethanol permeability than the human stratum corneum, said diffusion-control membrane controlling ethanol and water vapor flux from the skin to the sensor cell. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification