Prefillable syringes and injectors for use therewith

• US 5,944,694 A
• Filed: 11/12/1996
• Issued: 08/31/1999
• Est. Priority Date: 11/12/1996
• Status: Expired due to Fees

• Current Assignee: Medrad Incorporated (Bayer AG)
• Original Assignee: Medrad Incorporated (Bayer AG)
• Inventors: Rhinehart, Edward J., Hitchins, Mark W., Masarik, Robert J.
• Primary Examiner(s): Coggins, Wynn Wood
• Assistant Examiner(s): Thanh, LoAn H.
• Application Number:
  US08/748,230
• Time in Patent Office: 1,022 Days
• Field of Search: 604/131, 604/151, 604/152, 604/154, 604/155, 604/181, 604/187, 604/189
• US Class Current: 604/154
• CPC Class Codes: A61M 5/14546 Front-loading type injectors
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump

Abstract

The present invention provides prefillable syringes and injectors for use therewith that expand and/or facilitate a variety of medical procedures involving the injection of a liquid medium. In several embodiments, the present syringes and injectors enable the use of current syringe materials at higher pressures than previously attainable or the use of other materials not previously usable with current high pressure-syringe and injector designs. In one embodiment, a syringe comprises an elongated cylindrical main body having a first pair and a second pair of mounting flanges encompassing collectively an arcuate length equal to at least approximately 180° of the circumference of the rear portion of the cylindrical main body for releasably mounting the syringe in a desired position relative to the front wall of the injector housing. Injectors for use with such syringes comprise a housing having a front wall and a retainer on the front wall which cooperates with the first and second pairs of mounting flanges of the syringe to releasably mount the syringe on the injector.

Claims

1. An injector for injecting a liquid medium from a syringe having at least two pairs of mounting flanges operably associated therewith, the injector comprising:

a housing having a front wall; and

a retainer disposed on the front wall, the retainer defining at least four slots therein for receiving therethrough the at least two pairs of mounting flanges on the syringe, the retainer further comprising at least two pairs of retaining flanges to releasably engage the at least two pairs of mounting flanges when the syringe is mounted within the retainer, the first pair of retaining flanges being positioned at a first axial location on the retainer and the second pair of retaining flanges being positioned at a second axial location on the retainer, the first and second pairs of retaining flanges being radially offset from one another, whereby the at least four slots and the at least two pairs of retaining flanges on the retainer cooperate with the at least two pairs of mounting flanges associated with the syringe to releasably engage the syringe with the injector.

2. The injector of claim 1 wherein the retainer comprises means for preventing improper engagement of the at least two pairs of mounting flanges to the retainer.

3. The injector of claim 1 wherein the retainer further comprises a third pair of retaining flanges positioned at a third axial location on the retainer to releasably engage a third set of mounting flanges on the syringe.

4. The injector of claim 1 wherein the first pair of retaining flanges are radially offset from the second pair of retaining flanges by approximately 90°

.

5. The injector of claim 1 wherein the at least two pairs of mounting flanges encompass collectively an arcuate length equal to at least approximately 180°

of the circumference of the rear portion of the main body.

6. The injector of claim 1 wherein the mounting flanges of the first pair of mounting flanges are positioned symmetrically about the axis of the main body and the mounting flanges of the second pair of mounting flanges are positioned symmetrically about the axis of the main body.

7. The injector of claim 1 wherein the mounting flanges of the first pair of mounting flanges are dimensioned differently from the mounting flanges of the second pair of mounting flanges.

8. The injector of claim 1 wherein the syringe further comprises a generally conical transition region positioned at a front end portion of the main body, a wall thickness of the conical transition region and a wall thickness of the main body being thickened in the vicinity of the intersection of the main body and the generally conical transition region to structurally reinforce the syringe in the vicinity of the intersection region.

9. The injector of claim 1 wherein the syringe further comprises:

an injection region having a diameter less than the main body; and

a transition region connecting the main body and the injection region, the transition region having a generally hemispherical shape.

10. A system for injecting a liquid medium, comprising a syringe and an injector, the syringe comprising:

a main body; and

a releasable mounting mechanism comprising at least two pairs of mounting flanges operably associated with the main body;

the injector comprising;

a housing; and

a cooperating retainer disposed housing, the cooperating retainer defining at least four slots therein for receiving therethrough the at least two pairs of mounting flanges on the syringe, the cooperating retainer further comprising at least two pairs of retaining flanges to releasably engage the at least two pairs of mounting flanges when the syringe is mounted within the cooperating retainer, the first pair of retaining flanges being positioned at a first axial location on the retainer and the second pair of retaining flanges being positioned at a second axial location on the retainer, the first and second pairs of retaining flanges being radially offset from one another, whereby the at least four slots and the at least two pairs of retaining flanges on the retainer cooperate with the at least two pairs of mounting flanges associated with the syringe to releasably engage the syringe with the injector.

11. The system of claim 10 further comprising means for preventing improper engagement of the at least two pairs of mounting flanges to the retainer.

12. The system of claim 10 wherein the syringe comprises at least one indicator representing information regarding the contents of the syringe and the injector comprises at least one sensor adapted to read the information represented on the indicator.

13. The system of claim 10 wherein the first pair of mounting flanges are radially offset from the second pair of mounting flanges by approximately 90°

.

14. The system of claim 10 wherein the at least two pairs of mounting flanges encompass collectively an arcuate length equal to at least approximately 180°

of the circumference of the rear portion of the main body.

15. The system of claim 10 wherein the mounting flanges of the first pair of mounting flanges are positioned symmetrically about the axis of the main body and the mounting flanges of the second pair of mounting flanges are positioned symmetrically about the axis of the main body.

16. The system of claim 10 wherein the mounting flanges of the first pair of mounting flanges are dimensioned differently from the mounting flanges of the second pair of mounting flanges.

17. The system of claim 10 wherein the syringe further comprises a generally conical transition region positioned at a front end portion of the main body, a wall thickness of the conical transition region and a wall thickness of the main body being thickened in the vicinity of the intersection of the main body and the generally conical transition region to structurally reinforce the syringe in the vicinity of the intersection region.

18. The system of claim 10 wherein the syringe further comprises:

an injection region having a diameter less than the main body; and

a transition region connecting the main body and the injection region, the transition region having a generally hemispherical shape.

19. An injection apparatus comprising, in combination:

a syringe comprising;

a main body comprising a rear portion; and

at least two pairs of mounting flanges connected to the rear portion of the main body, the first pair of mounting flanges being positioned at a first axial location on the syringe and the second pair of mounting flanges being positioned at a second axial location on the syringe, the first pair of mounting flanges being radially offset from the second pair of mounting flanges; and

an injector comprising;

a housing having a front wall; and

a retainer on the front wall including at least four slots for receiving therethrough the at least two pairs of mounting flanges on the syringe, the retainer further comprising at least two pairs of retaining flanges to releasably engage the at least two pairs of mounting flanges when the syringe is mounted within the retainer, the first pair of retaining flanges being positioned at a first axial location on the cooperating retainer to engage the first pair of mounting flanges and the second pair of retaining flanges being positioned at a second axial location on the cooperating retainer to engage the second pair of mounting flanges, the first pair of retaining flanges being radially offset from the second pair of retaining flanges, whereby the at least four slots and the at least two pairs of retaining flanges of the retainer are positioned to receive the at least two pairs of mounting flanges on the syringe when the syringe is releasably mounted on the front wall of the housing.

20. An injector for injecting a liquid medium from a syringe having at least three pairs of mounting flanges operably associated therewith, the injector comprising:

a housing; and

a retainer disposed on the housing and defining at least four slots therein for receiving therethrough the at least three pairs of mounting flanges on the syringe, the retainer further comprising at least three pairs of retaining flanges to releasably engage the at least three pairs of mounting flanges when the syringe is mounted within the retainer, the first, second and third pairs of retaining flanges being positioned at different axial locations on the retainer, and at least one of the first, second and third pairs of retaining flanges being radially offset from the other of the first, second and third pair of retaining flanges, whereby the at least four slots and the at least three pairs of retaining flanges on the retainer cooperate with the at least three pairs of mounting flanges associated with the syringe to releasably engage the syringe with the injector.