Chemoprevention of metachronous adenomatous colorectal polyps
First Claim
1. A method for protecting a colorectum against a recurrence of colorectal adenomas comprising administering to a human afflicted with colorectal adenomas, an amount of ursodeoxycholic acid or a pharmaceutically-acceptable salt thereof, effective to prevent the recurrence of colorectal adenomas following the removal thereof and administering an effective amount of a nonsteroidal anti-inflammatory agent, wherein the nonsteroidal anti-inflammatory agent is a phenolic NSAID.
0 Assignments
0 Petitions
Accused Products
Abstract
A method for protecting a colorectum against a recurrence of adenomas is provided, wherein ursodeoxycholic acid or an amide-conjugate thereof, or ursodeoxycholic acid or an amide-conjugate thereof in combination with sulindac or a phenolic NSAID is administered to a patient afflicted with colorectal adenomas in an amount effective to prevent the recurrence of colorectal adenomas following the removal thereof.
-
Citations
3 Claims
- 1. A method for protecting a colorectum against a recurrence of colorectal adenomas comprising administering to a human afflicted with colorectal adenomas, an amount of ursodeoxycholic acid or a pharmaceutically-acceptable salt thereof, effective to prevent the recurrence of colorectal adenomas following the removal thereof and administering an effective amount of a nonsteroidal anti-inflammatory agent, wherein the nonsteroidal anti-inflammatory agent is a phenolic NSAID.
Specification