Ionizing analysis apparatus
First Claim
1. An ionizing analysis apparatus which ionizes a sample material contained in an electrolytic solution in a chamber, emits thus obtained ion, and then detects thus emitted ion, said apparatus comprising:
- a supply tube which supplies the electrolytic solution into said chamber and has an opening within said chamber;
a needle having a tip disposed so as to oppose to said opening within said chamber;
a nozzle for jetting out a gas against any region between the tip of said needle and said opening from a direction substantially orthogonal to a longitudinal direction of said needle;
takeout means for taking out a droplet of said electrolytic solution by said needle; and
emitting means for emitting the droplet is into said chamber by the gas jetting out from said nozzle against the droplet taken out by said takeout means or said needle having the tip to which the droplet is attached.
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Accused Products
Abstract
A needle (22) adapted to advance and retract in z directions is accommodated in an ionization chamber (15), whereas an electrolytic solution (L) containing a sample is supplied into the ionization chamber (15) through a supply tube (18). The supply tube (18) is bored with a hole (20) communicating with the inside of the ionization chamber (15). While a predetermined voltage is applied between the supply tube (18) and the needle (22), the tip of the needle (22) is caused to come close to but not in contact with the electrolytic solution in the hole (20), so as to form a locally raised portion (Taylor cone) in the liquid surface of the electrolytic solution, thereby attaching a droplet containing ions in the electrolytic solution to the tip of the needle (22). After the needle (22) is moved to a predetermined position, N2 gas is jetted against the tip portion of the needle (22), thereby emitting the droplet containing ions attached to the tip of the needle (22) into the ionization chamber (15). Accordingly, the ions can be concentrated and subjected to soft ionization. Thus, an analysis apparatus for improving the ion generating efficiency to be used for mass spectrometry or the like is provided.
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Citations
36 Claims
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1. An ionizing analysis apparatus which ionizes a sample material contained in an electrolytic solution in a chamber, emits thus obtained ion, and then detects thus emitted ion, said apparatus comprising:
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a supply tube which supplies the electrolytic solution into said chamber and has an opening within said chamber; a needle having a tip disposed so as to oppose to said opening within said chamber; a nozzle for jetting out a gas against any region between the tip of said needle and said opening from a direction substantially orthogonal to a longitudinal direction of said needle; takeout means for taking out a droplet of said electrolytic solution by said needle; and emitting means for emitting the droplet is into said chamber by the gas jetting out from said nozzle against the droplet taken out by said takeout means or said needle having the tip to which the droplet is attached. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. An ionizing analysis apparatus which ionizes a sample material contained in an electrolytic solution in a chamber, emits thus obtained ion, and then detects thus emitted ion, said apparatus comprising:
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a supply tube which supplies said electrolytic solution into said chamber and has an opening within said chamber; a needle which is disposed in said tube, has a tip projecting into said chamber through said opening, and is movable in a longitudinal direction thereof; and a nozzle for jetting out a gas against the tip of said needle from a direction substantially orthogonal to the moving direction of said needle. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. An ionizing analysis apparatus which ionizes a sample material contained in an electrolytic solution in a chamber, emits thus obtained ion, and then detects thus emitted ion, said apparatus comprising:
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a supply tube which supplies said electrolytic solution into said chamber and has an opening within said chamber; a first needle in which at least a tip thereof is disposed within said chamber; a second needle which has a tip opposed to the tip of said first needle and is disposed within said tube so as to be relatively movable with respect to said first needle; and a nozzle for jetting out a gas against the tip of said second needle from a direction substantially orthogonal to the moving direction of said second needle. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34)
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35. An ionizing analysis apparatus which ionizes a sample material contained in an electrolytic solution in a chamber, emits thus obtained ion, and then detects thus emitted ion, said apparatus comprising:
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a supply tube which supplies the electrolytic solution into said chamber and has an opening within said chamber; a needle disposed within said chamber; takeout means for taking out a droplet of said electrolytic solution by said needle, wherein said takeout means comprises means for generating a Taylor cone by vibrating said supply tube so as to vibrate a liquid surface of said opening; and emitting means for emitting said droplet into said chamber by gas jetting out against said droplet taken out by said takeout means preferably with applying a predetermined voltage, corresponding to a charge polarity of said ion in said droplet taken out, to said needle.
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36. An ionizing analysis apparatus which ionizes a sample material contained in an electrolytic solution in a chamber, emits thus obtained ion, and then detects thus emitted ion, said apparatus comprising:
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a supply tube which supplies the electrolytic solution into said chamber and has an opening within said chamber; a needle having a tip disposed within said chamber; takeout means for taking out a droplet of said electrolytic solution by said needle wherein said takeout means comprises means for bringing a liquid surface of said opening into contact with said tip of said needle by vibrating said supply tube so as to vibrate said liquid surface; and emitting means for emitting said droplet into said chamber by gas jetting out against said droplet taken out by said takeout means preferably with applying a predetermined voltage, corresponding to a charge polarity of said ion in said droplet taken out, to said needle.
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Specification