Computer operated material processing systems and method
First Claim
1. A computer operated material processing apparatus comprising:
- a centrifuge tube for containing a liquid mixture and adapted for rotation about an axis by a mechanically driven rotor so as to subject the mixture to centrifugal forces;
a scanning device for detecting the presence of specific test particles injected into the mixture and generating scanning signals in accordance therewith;
an injector for injecting test particles into the mixture, said test particles being detectable by said scanning device and having a sedimentation constant approximately equal to a component of the mixture that is desired to be separated;
a computer for analyzing the scanning signals and controlling the rotation of the centrifuge tube in accordance with the scanning signals so as to localize said specific particles in a desired sedimentation layer of said tube; and
a reaction column comprising immobilized molecules with a specific binding affinity for said test particles for removing said test particles when said mixture is passed therethrough.
0 Assignments
0 Petitions
Accused Products
Abstract
Improvements in computer controlled material processing are disclosed including an apparatus and method in which the centrifugation of a liquid mixture in order to separate out components of the mixture with different sedimentation rates is adaptively controlled by monitoring the sedimentation of detectable particles and controlling the centrifugation so as to effect a desired localization of the detectable particles. Such adaptive control may be performed with a continuous flow centrifugal separator or a batch-type centrifuge. The detectable particles may be test particles having a sedimentation constant approximately equal to a component of interest in the mixture whose localization is desired.
-
Citations
8 Claims
-
1. A computer operated material processing apparatus comprising:
-
a centrifuge tube for containing a liquid mixture and adapted for rotation about an axis by a mechanically driven rotor so as to subject the mixture to centrifugal forces; a scanning device for detecting the presence of specific test particles injected into the mixture and generating scanning signals in accordance therewith; an injector for injecting test particles into the mixture, said test particles being detectable by said scanning device and having a sedimentation constant approximately equal to a component of the mixture that is desired to be separated; a computer for analyzing the scanning signals and controlling the rotation of the centrifuge tube in accordance with the scanning signals so as to localize said specific particles in a desired sedimentation layer of said tube; and a reaction column comprising immobilized molecules with a specific binding affinity for said test particles for removing said test particles when said mixture is passed therethrough. - View Dependent Claims (2, 3, 4, 5, 6, 8)
-
-
7. An adaptively controlled centrifugal separator comprising:
-
a housing into which may be flowed an input stream of a feedstock liquid whose components are desired to be separated, said housing containing an impeller for imparting rotation to the liquid contained therein and subject the fluid to centrifugal forces causing separation of components making up the liquid in accordance with density, said separated components making up a plurality of output streams; a scanning device for detecting the presence of specific test particles in a stream and generating scanning signals in accordance therewith; an injector for injecting test particles into the feedstock liquid, said test particles being detectable by said scanning device and having a sedimentation constant approximately equal to a component of the feedstock liquid whose concentration in a particular stream is desired to be controlled; a computer for analyzing the scanning signals, determining the concentration of particles in a particular stream, and controlling the rotation of the impeller so as to maintain a desired concentration of said specific particles in a particular stream; and a reactor column into which is flowed a particular stream, said reactor column containing immobilized molecules for removing said test particles by binding therewith.
-
Specification