Diagnostic for determining the time of a heart attack
First Claim
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1. A method for determining a time of a myocardial infarction in a patient, comprising a step of:
- determining a ratio of oxidized to reduced troponin I in a blood sample obtained from the patient within 24 hours of the myocardial infarction, where the ratio reflects an amount of time elapsed from the time of the myocardial infarction.
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Abstract
The present invention relates to methods for determining the time of a myocardial infarction in a patient by measuring the ratio of oxidized to reduced troponin I in a blood sample obtained from the patient. This ratio is measured through the use of two or more distinct components which specifically bind oxidized troponin I, reduced troponin I, and/or both forms of troponin I present in the blood sample. Each distinct component may be an antibody or an antibody fragment. The measured ratio reflects the time elapsed from the time of the myocardial infarction.
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Citations
19 Claims
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1. A method for determining a time of a myocardial infarction in a patient, comprising a step of:
determining a ratio of oxidized to reduced troponin I in a blood sample obtained from the patient within 24 hours of the myocardial infarction, where the ratio reflects an amount of time elapsed from the time of the myocardial infarction. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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