Closure prothesis for transcatheter placement
First Claim
1. A closure prosthesis for sealing an opening in a fluid passageway within a living body, comprising:
- a resiliently flexible sealing element;
at least one flexible restraining element fixedly attached and extendable along at least a portion of one side of said sealing element, said restraining element and said sealing element defining an integral closure element;
said integral closure element compressible into a reduced insertion configuration suitable for insertion through the fluid passageway and the opening but tending to self-expand to a relatively thin shape with a surface area capable of covering the opening; and
said fixedly attached restraining element having a first insertion form suitable for insertion through the fluid passageway and a second insertion form for passage through the opening, said restraining element tending to self-expand to a restraining configuration extending adjacent said one side of said sealing element such that said integral closure element pinches an edge of the opening between a portion of said restraining element and said sealing element.
1 Assignment
0 Petitions
Accused Products
Abstract
A closure prosthesis and transcatheter delivery system are disclosed, wherein the closure prosthesis seals across an opening of a fluid passageway within a living body. The closure prosthesis is a flexible disk including a flexible ring and diaphragm having a plurality of hollow flexible wire segments attached thereto. Delivery of the closure prosthesis is accomplished using a hollow sheath and a pusher catheter slidable within the sheath, wherein filaments are looped through the wire segments to releasably connect the disk to the pusher catheter. The disk is resiliently compressed within the sheath and, upon release therefrom, the disk resiliently expands into a larger, unrestrained shape. Tension applied to the filaments resiliently bends the wire segments so that they may be drawn through the opening of the defect. Upon releasing the filaments from the disk, the wire segments resiliently expand to trap the disk in place to seal across the opening.
270 Citations
15 Claims
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1. A closure prosthesis for sealing an opening in a fluid passageway within a living body, comprising:
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a resiliently flexible sealing element; at least one flexible restraining element fixedly attached and extendable along at least a portion of one side of said sealing element, said restraining element and said sealing element defining an integral closure element; said integral closure element compressible into a reduced insertion configuration suitable for insertion through the fluid passageway and the opening but tending to self-expand to a relatively thin shape with a surface area capable of covering the opening; and said fixedly attached restraining element having a first insertion form suitable for insertion through the fluid passageway and a second insertion form for passage through the opening, said restraining element tending to self-expand to a restraining configuration extending adjacent said one side of said sealing element such that said integral closure element pinches an edge of the opening between a portion of said restraining element and said sealing element. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A flexible closure prosthesis and transcatheter delivery system, wherein said closure prosthesis seals across an opening of a fluid passageway within a living body, comprising:
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a flexible sealing element; a flexible restraining element attached to said sealing element, said sealing element and said restraining element defining an integral closure prosthesis; a hollow sheath; a pusher catheter slidable within said sheath; said integral closure prosthesis deformable into a first insertion form constrainable within said sheath for delivery adjacent the opening, said closure prosthesis being self-expandable upon release from said sheath into a first operational form that is larger than said first insertion form; and said flexible restraining element deformable into a second insertion form, said flexible restraining element self-expanding upon release into a second operational form that is larger than said second insertion form, wherein said sealing element seals across the opening and said restraining element restrains said closure prosthesis across the opening. - View Dependent Claims (9, 10, 11, 12, 13)
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14. A method for delivering a closure prosthesis for sealing across an opening of a fluid passageway within a living body, comprising:
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providing a closure prosthesis including a flexible sealing element and a flexible restraining element attached thereto; inserting the closure prosthesis into a living body adjacent the opening, the closure prosthesis maintained in a reduced size first insertion form; deploying the closure prosthesis, the closure prosthesis self-expanding into a first operational form larger than said first insertion form and sized to prevent passage through the opening; after deploying, compressing the restraining element portion of the closure prosthesis into a second insertion form for passage through the opening; moving the restraining element portion of the closure prosthesis through the opening; and releasing the restraining element portion of the closure prosthesis, the restraining elements self-expanding into a second operational form larger than the second insertion form, wherein said sealing element seals across the opening and said restraining element restrains said closure prosthesis in place across the opening. - View Dependent Claims (15)
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Specification