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Field-release mass spectrometry

  • US 5,952,654 A
  • Filed: 10/29/1997
  • Issued: 09/14/1999
  • Est. Priority Date: 10/29/1997
  • Status: Expired due to Fees
First Claim
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1. A method of releasing a substrate into a vacuum or gas phase, comprisinga) covalently or ligandly binding said substrate to the tip of a first electrode via a release group, which release group is cleavable in response to applied energy;

  • b) introducing an electrical field so as to establish a charge potential between said first electrode and a second electrode separated from said first electrode via a vacuum or gas phase, the strength of such field sufficient to bristle said covalently-bound or ligandly-bound substrate; and

    c) applying sufficient energy to said release group to cleave said release group and thereby release said substrate into a vacuum or gas phase.

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