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Noninvasive system and method for identifying coronary disfunction utilizing electrocardiography derived data

  • US 5,954,664 A
  • Filed: 08/07/1997
  • Issued: 09/21/1999
  • Est. Priority Date: 04/06/1995
  • Status: Expired due to Term
First Claim
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1. An ECG system for practicing a noninvasive method of investigating cardiac status of a subject and enabling classification of said subject into normal and abnormal cardiac categories utilizing electrocardiography ECG data obtained therefrom, said method comprising, in a functional sequence, performance of the steps of:

  • a. obtaining data from ECG cycle(s) from each of a multiplicity of members of a population of subjects who have been documented as normal subjects, in that they do not show risk factors for, or demonstrate detectable cardiac abnormality, by providing, selecting and monitoring at least one lead(s) of said ECG system;

    b. establishing criteria for, and in line therewith selecting some ECG cycle portion and defining cycle portion data points therewithin, and calculating an average selected ECG cycle portion data set for said at least one monitored ECG system lead(s) by, for a monitored ECG system lead, a procedure comprising combining corresponding ECG cycle portion data points for said selected ECG cycle portion for ECG cycle(s) obtained from each of a number of members of said multiplicity of members of a population of subjects who have been documented as normal subjects, each said calculated average selected ECG cycle portion data set being a composite data set of said selected ECG cycle portion for said population of normal subjects, for a monitored ECG system lead;

    c. obtaining data from ECG cycle(s) from a subject, by monitoring at least one lead(s) of said ECG system, said ECG system lead(s) monitored being the same as the monitored ECG system lead(s) utilized in step a. to obtain data utilized in step b.;

    d. selecting some ECG cycle portion, which is essentially that selected in step b., and calculating an average selected ECG cycle portion data set for said at least one monitored ECG system lead(s) by, for a monitored ECG system lead, a procedure comprising combining corresponding ECG cycle portion data points for said selected ECG cycle portion for ECG cycle(s) obtained from said subject, each said calculated average selected ECG cycle portion data set being a composite data set of said selected ECG cycle portion for said subject, for a monitored ECG system lead;

    e. calculating corresponding representative parameter(s) from resulting composite data sets calculated in steps b. and d., for monitored ECG system lead(s), for, respectively, said normal subject population and said subject;

    f. comparing subject to corresponding normal subject population representative parameter(s), and combining results thereof to arrive at a "score", the magnitude of which "score" results from difference(s) between magnitude(s) of corresponding normal subject population, and subject representative parameter(s), which "score" magnitude increases when said difference(s) in magnitude(s) between corresponding normal subject population, and subject, representative parameter(s) increase, the magnitude of which "score" provides an indication of the cardiac status of said subject, with a "score" near zero being indicative of a subject properly categorized as a cardiac normal in that the magnitude(s) of subject representative parameter(s) are generally more closely matched to the magnitude(s) of corresponding normal subject population representative parameter(s), and with a progressively higher "score" being indicative of a subject progressively more properly categorized as a cardiac abnormal in that the magnitude(s) of subject representative parameter(s) are generally progressively less closely matched to the magnitude(s) of corresponding normal subject population representative parameter(s);

    g. providing an output means for presenting said score;

    said ECG system comprising ECG lead(s) which monitor electrodes affixed to a subject or member of a normal subject population, and which provide monitored signal(s) to an ECG monitor, said ECG monitor being functionally interconnected to a computational means which is programmed to accept ECG data from said ECG monitor and practice the method of steps a.-f., said computational means being functionally interconnected to an output means to enable practice of step g.

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