Fluid delivery device with fill adapter

• US 5,957,891 A
• Filed: 12/16/1997
• Issued: 09/28/1999
• Est. Priority Date: 10/11/1995
• Status: Expired due to Fees

• Current Assignee: Pescadero Beach Holdings Corporation
• Original Assignee: Science Incorporated
• Inventors: Barber, Steven C., Feng, William W., Kazemzadeh, Farhad, Kriesel, Marshall S, Kluck, William J., Kriesel, Matthew B.
• Primary Examiner(s): MCDERMOTT, CORRINE MARIE
• Application Number:
  US08/991,123
• Time in Patent Office: 651 Days
• Field of Search: 604/131, 604/132, 604/151, 604/153, 604/890.1, 604/246, 128/DIG. 12
• US Class Current: 604/132
• CPC Class Codes: A61M 2005/14513 with secondary fluid driving or regulating the infusion
• CPC Class Codes: A61M 2005/1581 Right-angle needle-type devices
• CPC Class Codes: A61M 2205/197 by the seal material
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/152 pressurised by contraction of elastic reservoirs containers for dispensing contents by contraction of an elastic bag provided therein, in general B65D83/0061
• CPC Class Codes: A61M 5/158 Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
• CPC Class Codes: Y10S 128/12 Pressure infusion

Abstract

A fluid delivery device having a self-contained stored energy membrane for expelling fluids at a precisely controlled rate which is of a compact, laminate construction. The device also includes a novel adapter which is usable to fill the reservoir of the device using a compatable filling syringe apparatus which is mateable with the adapter.

Claims

1. A fluid delivery device for infusing medicinal fluids into a patient at a controlled rate comprising:

(a) a base having a lower surface and a fill port;

(b) stored energy means for forming, in conjunction with said base, a reservoir having an inlet port and an outlet port, said stored energy means comprising at least one distendable membrane superimposed over said base, said membrane being distendable as a result of pressure imparted by liquids introduced into said reservoir to establish internal stresses, said stresses tending to move said membrane toward a less distended configuration;

(c) infusion means for infusing medicinal fluids from said fluid reservoir into the patient, said infusion means comprising a hollow cannula having an inlet in communication with said outlet port of said reservoir;

(d) cover means connected to said base for covering said distendable membrane; and

(e) filling means connected to said base for filling said reservoir, said filling means comprising;

(i) a septum assembly, including a pierceable septum sealably disposed within said fill port of said base;

(ii) a filling syringe having a housing, a fluid reservoir within said housing, and a hollow cannula carried by said housing for communication with said fluid reservoir; and

(iii) a fill adapter connected to said lower surface of said base and extending outwardly therefrom, said fill adapter including a wall portion defining an opening closely receiving at least a portion of said housing of said filling syringe.

2. A device as defined in claim 1 in which said wall portion of said adapter defines a generally oval shaped opening and in which at least a portion of said housing of said filling syringe is generally oval shaped for insertion into said oval shaped opening.

3. A device as defined in claim 1 further including flow control means disposed between said reservoir and said infusion means for controlling fluid flow from said reservoir.

4. A device as defined in claim 1, further including ullage defining means disposed within said reservoir for providing ullage within said reservoir, said ullage defining means comprising a dome shaped protuberance formed on said base.

5. A device as defined in claim 1 in which said septum assembly comprises a septum housing receivable within said fill port of said base and an elastomeric, pierceable core sealably disposed within said septum housing.

6. A device as defined in claim 1 in which said hollow cannula of said infusion means is connected to and supported by said base.

7. A device as defined in claim 1 in which said hollow cannula of said infusion means is connected to a subcutaneous infusion device spaced a part from said base.

8. A device as defined in claim 1 in which said fill adapter is removably connected to said base.

9. A device as defined in claim 1 in which said fill adapter includes an upper wall portion and a lower wall portion, said lower wall portion being separable from said upper wall portion.

10. A fluid delivery device for infusing medicinal fluids into a patient at a controlled rate comprising:

(a) a base having an upper surface including a central portion and a peripheral portion circumscribing said central portion, a lower surface engageable with the patient and an intermediate portion disposed between said upper and lower surfaces, said intermediate portion having a fill port formed therein;

(b) stored energy means for forming, in conjunction with said base, a reservoir having an inlet port and an outlet port, said stored energy means comprising at least one distendable membrane superimposed over said base, said membrane being distendable as a result of pressure imparted by liquids introduced into said reservoir to establish internal stresses, said stresses tending to move said membrane toward a less distended configuration;

(c) infusion means for infusing medicinal fluids from said fluid reservoir into the patient, said infusion means comprising a hollow cannula having an inlet in communication with said outlet port of said reservoir;

(d) cover means connected to said base for covering said distendable membrane; and

(e) filling means connected to said base for filling said reservoir, said filling means comprising;

(i) a septum assembly, including a pierceable septum sealably disposed within said fill port of said base;

(ii) a filling syringe, including a housing, a container having a fluid reservoir disposed within said housing and a hollow piercing needle carried by said housing for communication with said fluid reservoir; and

(iii) a fill adapter connected to said lower surface of said base, said fill adapter including an upper wall portion and a lower wall portion defining an opening closely receiving at least a portion of said housing of said filling syringe, at least a part of said fill adapter being removable from said base.

11. A device as defined in claim 10 in which said stored energy means comprises first and second distendable membranes.

12. A device as defined in claim 10 in which said wall portion of said adapter defines a generally oval shaped opening and in which at least a portion of said housing of said filling syringe is generally oval shaped for insertion into said oval shaped opening.

13. A device as defined in claim 10, further including ullage defining means disposed within said reservoir for providing ullage within said reservoir, said ullage defining means comprising a dome shaped protuberance formed on said base.

14. A device as defined in claim 10 in which said septum assembly comprises a septum housing receivable within said fill port of said base and an elastomeric, pierceable core sealably disposed within said septum housing.

15. A device as defined in claim 14 in which said septum housing includes a non-circular shaped connector base and in which said fill adapter includes a connector means for engagement with said non-circular shaped connector base for interconnecting said fill adapter with said septum housing upon rotation of said fill adapter relative to said septum housing.

16. A device as defined in claim 14 in which said lower wall portion is separable from said upper wall portion.

17. A fluid delivery device for infusing medicinal fluids into a patient at a controlled rate comprising:

(a) a base having an upper surface including a central portion and a peripheral portion circumscribing said central portion, a lower surface engageable with the patient and an intermediate portion disposed between said upper and lower surfaces, said intermediate portion having a fill port formed therein;

(b) stored energy means for forming, in conjunction with said base, a reservoir having an inlet port and an outlet port, said stored energy means comprising at least one distendable membrane superimposed over said base, said membrane being distendable as a result of pressure imparted by liquids introduced into said reservoir to establish internal stresses, said stresses tending to move said membrane toward a less distended configuration;

(c) infusion means for infusing medicinal fluids from said fluid reservoir into the patient, said infusion means comprising a hollow cannula having an inlet in communication with said outlet port of said reservoir;

(d) flow control means disposed between said reservoir and said infusion means for controlling liquid flow from said reservoir;

(e) cover means connected to said base for covering said distendable membrane; and

(f) filling means connected to said base for filling said reservoir, said filling means comprising;

(i) a septum assembly, including a septum housing receivable within said fill port of said base and an elastomeric, pierceable core sealably disposed within said septum housing;

(ii) a filling syringe, including a housing, a container having a fluid reservoir disposed within said housing and a hollow piercing needle carried by said housing for communication with said fluid reservoir; and

(iii) a fill adapter removably connected to said lower surface of said base, said fill adapter including an upper wall portion and a lower wall portion defining an opening closely receiving at least a portion of said housing of said filling syringe, at least a part of said fill adapter being removable from said base.

18. A device as defined in claim 17 in which said septum housing includes a non-circular shaped connector base and in which said fill adapter includes a connector means for engagement with said non-circular shaped connector base for interconnecting said fill adapter with said septum housing upon rotation of said fill adapter relative to said septum housing.

19. A device as defined in claim 17 in which said wall upper portion of said adapter defines a generally oval shaped opening and in which at least a portion of said housing of said filling syringe is generally oval shaped for insertion into said oval shaped opening.

20. A device as defined in claim 17, further including ullage defining means disposed within said reservoir for providing ullage within said reservoir, said ullage defining means comprising a dome shaped protuberance formed on said base.

21. A device as defined in claim 17 in which said stored energy means comprises first and second distendable membranes.

22. A device as defined in claim 17 further including means for sealably closing said opening in said lower wall portion of said fill adapter.

23. A device as defined in claim 17 in which said flow control means comprises a porous flow rate control frit.

24. A device as defined in claim 17 in which said flow control means comprises a flow control wafer having a very small laser drilled aperture formed therein.

25. A device as defined in claim 17 in which said cover means includes a soft, pliable elastomeric overcover.

26. A device as defined in claim 17 in which said cover means includes a soft, pliable elastomeric overcover having resiliently deformable edge and corner portions.

27. A device as defined in claim 17 in which one of said cover means and said base includes at least one generally circular groove and in which the other of said cover means and said base includes at least one protuberance receivable within said groove.

28. A device as defined in claim 17 in which said cover means comprises a cover having a pair of generally circular shaped, rim-like protuberances and in which said base includes a pair of generally circular shaped grooves indexable with said protuberances.

29. A device as defined in claim 28 in which a portion of said distendable membrane is disposed between said protuberances and said grooves.