Thin film sample support
First Claim
1. A sample holder for retaining a liquid sample in a localized region and configured for subsequent analytical processing in a beam of electromagnetic radiation, the sample holder comprising:
- a substantially planar sample support surface for providing a localized region for receiving a test sample and having a central portion and an exterior portion disposed to substantially surround the central portion, one of the central portion and the exterior portion having a hydrophilic surface, and the other of the central portion and the exterior portion having a hydrophobic surface, the central and exterior portions of the sample support surface being formed of a material which resists spectral contamination.
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Accused Products
Abstract
A sample support for holding for samples for use with an analysis instrument. The sample support is particularly beneficial for use with analysis instruments which rely on a beam of radiation or accelerated particles and a method for making the same is disclosed. The holder includes a frame with one or more orifices covered by a support surface, typically in the form of a thin polymer film. The film is divided into hydrophobic and hydrophilic portions to isolate precise positions where samples can be placed to intersect a probe beam during analysis.
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Citations
26 Claims
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1. A sample holder for retaining a liquid sample in a localized region and configured for subsequent analytical processing in a beam of electromagnetic radiation, the sample holder comprising:
a substantially planar sample support surface for providing a localized region for receiving a test sample and having a central portion and an exterior portion disposed to substantially surround the central portion, one of the central portion and the exterior portion having a hydrophilic surface, and the other of the central portion and the exterior portion having a hydrophobic surface, the central and exterior portions of the sample support surface being formed of a material which resists spectral contamination. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A sample holder for retaining a liquid sample in a localized region and configured for subsequent analytical processing in a beam of electromagnetic radiation, the sample holder comprising:
a substantially planar sample support surface for providing a localized region for receiving a test sample and having a substantially planar base layer and a substantially planar secondary layer disposed on the base layer to provide a central portion and an exterior portion substantially surrounding the central portion, one of the base or secondary layers having a hydrophilic surface, and the other of the base or secondary layers having a hydrophobic material such that one of the central or exterior portions has a hydrophilic surface, and the other of the central or exterior portions has a hydrophobic surface, the base and secondary layers being formed of a material which resists spectral contamination. - View Dependent Claims (21, 22, 23, 24, 25, 26)
Specification