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Amino-cyclodextrin syntheses

  • US 5,959,089 A
  • Filed: 01/16/1996
  • Issued: 09/28/1999
  • Est. Priority Date: 07/19/1993
  • Status: Expired due to Fees
First Claim
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1. A compound of the formula ##STR35## wherein C is cyclodextrin, A is amino, azido or aralkoxycarbonyl-substituted amino, wherein said aralkoxy has 7 to 10 carbon atoms and n is 0, 1, 2 or 3, B is hydroxyl, or one of A and B is azido and the other is aralkoxycarbonyl-substituted amino, R is alkenyl of 2 to 6 carbon atoms, aminoalkyl of 3 to 6 carbon atoms, or azidoalkyl of 1 to 6 carbon atoms, wherein the OR group is in at least one of the -2 and -3 positions and with the proviso that when n is 0, R is aminoalkyl of 3 to 6 carbon atoms, or azidoalkyl;

  • and where A and when B is not hydroxyl, B are attached at the cyclodextrin deoxy primary hydroxyl sites, and R forms an etherified secondary hydroxyl group wherein the A, B groups are present exclusively at the primary hydroxyl side and the R group is present exclusively at the secondary hydroxyl side of the cyclodextrin.

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