Method for making a biodegradable stent

• US 5,968,092 A
• Filed: 05/22/1998
• Issued: 10/19/1999
• Est. Priority Date: 10/04/1991
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Corporation
• Original Assignee: Boston Scientific Corporation
• Inventors: Wang, Lixiao, Buscemi, Paul J., Stejskal, Elizabeth A., Palme, Donald F. II
• Primary Examiner(s): Yu, Mickey
• Assistant Examiner(s): Nguyen, Dinh X.
• Application Number:
  US09/083,341
• Time in Patent Office: 515 Days
• Field of Search: 623/1, 623/66, 623/11, 623/12, 600/36, 606/194, 606/195, 606/198, 427/2.24, 427/2.25
• US Class Current: 128/898
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2210/0023 operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir
• CPC Class Codes: A61L 2300/42 Anti-thrombotic agents, anticoagulants, anti-platelet agents
• CPC Class Codes: A61L 2300/604 Biodegradation
• CPC Class Codes: A61L 2300/606 Coatings
• CPC Class Codes: A61L 2300/622 Microcapsules
• CPC Class Codes: A61L 31/041 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 31/044 Collagen
• CPC Class Codes: A61L 31/047 Other specific proteins or polypeptides not covered by A61L31/044 - A61L31/046
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence
• CPC Class Codes: Y10S 623/901 Method of manufacturing prosthetic device

Abstract

A method for making a biodegradable stent for insertion into a lumen, the method involves the casting of a film including a matrix of collagen IV and laminin, drying the film, casting a film containing polylactic acid onto the first dried film to form stent material, drying the material formed and forming the biodegradable material into a stent.

Claims

1. A method for making a biodegradable stent for insertion into a lumen of a vessel of a living being, comprising:

casting a film that includes a matrix of collagen IV and laminin;

drying the film;

casting a film that includes polylactic acid onto the dried film that includes the matrix of collagen IV and laminin to form a stent material;

drying the stent material; and

forming the stent material into the biodegradable stent.

2. The method of claim 1 and further including plasma treating the film including the matrix of collagen IV and laminin after drying the film and before casting the film that includes polylactic acid onto the dried film.