Interchangeable multiple test system for portable analyzer

• US 5,968,329 A
• Filed: 05/06/1997
• Issued: 10/19/1999
• Est. Priority Date: 05/06/1997
• Status: Expired due to Term

• Current Assignee: Easydx Inc.
• Original Assignee: Diametrics Medical, Inc. (Allegro Biodiesel Corp.)
• Inventors: Hieb, Martin G., Crumm, Jon J., Anderson, Carter R., Sin, Kee Van
• Primary Examiner(s): Warden, Robert
• Assistant Examiner(s): NOGUEROLA, ALEXANDER STEPHAN
• Application Number:
  US08/851,970
• Time in Patent Office: 896 Days
• Field of Search: 204/400, 204/402, 204/403, 204/409, 205/775, 422/82.01, 422/82.02
• US Class Current: 204/402
• CPC Class Codes: G01N 33/4925 measuring blood gas content, e.g. O2, CO2 , HCO3

Abstract

A portable clinical system for providing a rapid electrochemical analysis of biological sera of interest at the point-of-care using a portable analyzer unit and a multi-sensor electrochemical plug-in cartridge analyzing system is disclosed which features a plug-in module including a reusable sensor cartridge having an inlet port for receiving a sample, an outlet drain port and array of self-calibrating electrochemical sensors, a plurality of electrical interfaced terminals for interfacing with the portable analyzer unit. An integral flushing system is provided for cleaning and allowing recalibration of the sensor between sample analyses. Connection devices on the analyzer unit and plug-in multi-use test module are provided for removably attaching the module to the analyzer unit. The connection devices are configured to receive a single-use sensor cartridge interchangeably and without modification with said plug-in multi-use test module.

Claims

1. A portable clinical system for providing a rapid electrochemical analysis of biological sera of interest at the point-of-care using a portable analyzer unit and a multi-sensor electrochemical plug-in cartridge analyzing system, the system further comprising;

(a) a self-contained plug-in module including;

(1) a reusable sensor cartridge having an inlet port for receiving fluid samples and flushing and recalibration solution, an outlet drain port, an array of self-calibrating electrochemical sensors and a plurality of electrical terminals for interfacing with the portable analyzer unit; and

(2) an integral flushing system for cleaning and allowing recalibration of said sensor to occur between sample analyses, including a system for supplying a flushing and recalibrating solution to said inlet port for displacing used samples and cleaning said sensors and a plurality of storage reservoirs including a reservoir for retaining used fluid and a reservoir for supplying unused flushing and calibration solution;

(b) matching connection devices on said analyzer unit and said plug-in module for removably attaching said module to said analyzer unit comprising a cartridge connection device provided on said analyzer configured to receive said reusable sensor cartridge of said plug-in module, said connection device on said analyzer also being configured to receive a separate single-use sensor cartridge interchangeably with said plug-in module without modification; and

wherein said integral flushing comprises hand-operated infusion pumping system including a pivoting arm carrying an outlet nozzle system,said rotating arm for aligning said nozzle system for infusing solution into said inlet port to displace used sample material and replace same with solution which allows recalibraiton of the sensors for the next sample.

2. The apparatus of claim 1 further comprising closure means in said plug-in module for closing said inlet port and preventing contamination between admission of samples.

3. The apparatus of claim 1 wherein said pivoting arm and outlet nozzle system of said infusion pumping system includes a nozzle having a directed fluid outlet in a generally lower surface that aligns and with closes the inlet port when said nozzle is positioned over said inlet port and wherein said arm pivots to expose the inlet port to allow a sample to be admitted.

4. The apparatus of claim 3 wherein said nozzle is resiliently mounted with respect to said inlet port, said nozzle system including resilient means for urging said lower surface of said nozzle against said inlet port.

5. The apparatus of claim 4 wherein said pivoting arm includes slots and wherein said nozzle is provided with a pair of protruding side tabs designed to snap-fit and be carried in said slots and further comprising a compression spring which urges said nozzle in the direction of said sensor cartridge.

6. The apparatus of claim 5 wherein said infusion pumping system includes a finger-operated reciprocating spray pump.

7. The apparatus of claim 6 further comprising additional stabilizing plug-in device between said analyzer unit and said module to stabilize the attachment of the plug-in module to the analyzer unit.

8. The apparatus of claim 4 wherein said infusion pumping system includes a finger-operated reciprocating spray pump.

9. The apparatus of claim 4 further comprising additional stabilizing plug-in device between said analyzer unit and said module to stabilize the attachment of the plug-in module to the analyzer unit.

10. The apparatus of claim 9 wherein the additional stabilizing plug-in device comprises a snap-fit plug and socket remote from said cartridge connection device.

11. The apparatus of claim 1 wherein said infusion pumping system includes a finger-operated reciprocating spray pump.

12. The apparatus of claim 1 further comprising additional stabilizing plug-in device between said analyzer unit and said module to stabilize the attachment of the plug-in module to the analyzer unit.

13. The apparatus of claim 12 wherein the additional stabilizing plug-in device comprises a snap-fit plug and socket remote from said cartridge connection device.