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Use of thermochromic liquid crystals in reflectometry based diagnostic methods

  • US 5,972,715 A
  • Filed: 12/23/1996
  • Issued: 10/26/1999
  • Est. Priority Date: 12/23/1996
  • Status: Expired due to Term
First Claim
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1. In an assay for the presence and/or concentration of an analyte in a fluid test sample in which the presence and/or concentration of the analyte is determined by measuring a color change in a solid test material using a reflectance spectrometer after the test material has been contacted with the fluid test sample and wherein assay results vary with changes in temperature of the solid test material, the improvement which comprises using the reflectance spectrometer to determine the temperature of the solid test material by measuring the reflectance of a thermochromic liquid crystal in close proximity to the solid test material and correcting the results of the assay for deviation in temperature of the solid test material from a pre-selected nominal temperature.

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