Surgical clips and methods for tissue approximation

• US 5,976,159 A
• Filed: 02/08/1996
• Issued: 11/02/1999
• Est. Priority Date: 02/24/1995
• Status: Expired due to Term

• Current Assignee: Heartport, Inc. (Johnson & Johnson)
• Original Assignee: Heartport, Inc. (Johnson & Johnson)
• Inventors: Gifford, Hanson S. III, Fann, James I., Bolduc, Lee R.
• Primary Examiner(s): Jackson, Gary
• Application Number:
  US08/598,513
• Time in Patent Office: 1,363 Days
• Field of Search: 606/215, 606/216, 606/220, 606/221, 606/228, 606/230, 606/153, 606/139, 606/213, 606/104, 606/142, 606/143, 606/151
• US Class Current: 606/142
• CPC Class Codes: A61B 17/064 Surgical staples, i.e. penetrating the tissue
• CPC Class Codes: A61B 17/0643 with separate closing member, e.g. for interlocking with staple
• CPC Class Codes: A61B 17/068 Surgical staplers , e.g. containing multiple staples or clampsstaplers containing only one staple A61B17/10; magazines or containers for staples A61B17/105; for performing anastomosis A61B17/115; staplers in general B25C5/00
• CPC Class Codes: A61B 17/11 for performing anastomosis; Buttons for anastomosis
• CPC Class Codes: A61B 17/115 Staplers for performing anastomosis in a single operation
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/12045 double occlusion, e.g. during anastomosis
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/0641 having at least three legs as part of one single body
• CPC Class Codes: A61B 2017/0647 having one single leg, e.g. tacks
• CPC Class Codes: A61B 2017/1103 Approximator
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61B 2017/1135 End-to-side connections, e.g. T- or Y-connections
• CPC Class Codes: A61B 2017/12127 Double occlusion, e.g. for creating blood-free anastomosis site
• CPC Class Codes: A61F 2002/30092 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol

Abstract

Surgical clips, and methods of use thereof, are provided for tissue approximation and attachment, and more particularly, for sealingly joining a graft vessel to a target vessel. The graft vessel has a free end and a graft vessel wall defining a graft lumen. The target vessel has a target vessel wall defining a target lumen and has an opening in the target vessel wall. The anastomosis clip includes a clip body having a distal extremity with a distal end and a proximal extremity with a proximal end. The distal end is configured to penetrate through the graft vessel wall near the free end and through the target vessel wall near the opening such that both the distal and proximal ends of the clip body are outside the graft and target vessels. At least a portion of the clip body is shapable so as to compress the graft vessel wall against the target vessel wall with the target vessel lumen in communication with the graft vessel lumen.

Claims

1. A surgical clip for approximating a first tissue layer to a second tissue layer, the surgical clip comprising a clip body having a distal extremity with a distal end, a proximal extremity with a proximal end and an outer surface therebetween, the distal end being configured to penetrate through both the first and second tissue layers from a first side to a second side thereof without penetrating the first and second tissue layers with the proximal extremity, wherein a first member selected from the distal extremity or the proximal extremity has an inner surface and is shapable into a closed position in which the first tissue layer is compressed against the second tissue layer between the inner surface and the outer surface with both the distal and proximal extremities disposed on the same side of the first and second tissue layers, the clip body being made of a biocompatible material which remains in the body indefinitely to ensure that the anastomosis remains intact, the clip body further having a middle portion configured to be held by a clip applier for applying the clip, the middle portion being separated from the distal extremity to allow penetration of the first and second tissue layers while the clip body is held by the clip applier.

2. The surgical clip of claim 1 wherein the distal extremity comprises a rigid shaft tapered to a point at its distal end.

3. The surgical clip of claim 2 wherein the shaft has a length of at least about twice the combined thickness of the first and second tissue layers.

4. The surgical clip of claim 3 wherein the distal extremity is disposed at a an angle of no more than about 120°

relative to the outer surface of the clip body in the open position.

5. The surgical clip of claim 1 wherein the first member comprises the proximal extremity, the proximal extremity being movable between an open position spaced apart from the distal extremity and the closed position closer to the distal extremity.

6. The surgical clip of claim 4 wherein an end portion of the proximal extremity is configured to extend across the distal extremity in the closed position.

7. The surgical clip of claim 6 wherein the end portion is bifurcated into two segments for extending across the distal extremity on opposing sides thereof and a slot between the segments for receiving the distal extremity.

8. The surgical clip of claim 4 wherein the proximal extremity is configured to contact the distal extremity in the closed position.

9. The surgical clip of claim 4 wherein the proximal extremity shields the distal end of the distal extremity in the closed position.

10. The surgical clip of claim 4 wherein the proximal extremity is generally inelastically deformable from the open position to the closed position.

11. The surgical clip of claim 1 wherein the first member comprises the distal extremity, the distal extremity being movable from an open position spaced apart from the proximal extremity and a closed position closer to the proximal extremity.

12. The surgical clip of claim 11 wherein the distal extremity is generally inelastically deformable between the open and closed positions.

13. The surgical clip of claim 11 wherein the inner surface of the distal extremity is disposed at a an angle of no more than about 120°

relative to the outer surface of the clip body in the open position.

14. The surgical clip of claim 1 further comprising a retainer attached to the distal extremity for retaining the first and second tissue layers thereon.

15. The surgical clip of claim 1 wherein the distal extremity is hook-shaped.

16. The surgical clip of claim 1 wherein the proximal extremity is configured to prevent the proximal extremity from passing through the first and second tissue layers.

17. The surgical clip of claim 16 wherein at least a portion of the proximal extremity has a larger cross-section than the distal extremity sufficient to prevent the portion from passing through the first and second tissue layers.

18. The surgical clip of claim 1 wherein the middle portion has a substantially larger cross-sectional area than the distal extremity.

19. The surgical clip of claim 1 wherein the middle portion has an aperture therein for receiving a portion of the clip applier.

20. The surgical clip of claim 1 wherein the middle portion comprises a flange substantially wider than the distal extremity for being held by the clip applier.

21. The surgical clip of claim 1 wherein the clip body includes a coupling for attachment to a flexible band.

22. The surgical clip of claim 1, wherein:

the clip body comprises a material selected from the group consisting of stainless steel, titanium, titanium alloy, tantalum, elgiloy, MP35N and cobalt chromium-nickel alloy.

23. The surgical clip of claim 1, wherein:

the clip body has a recess positioned between the distal and proximal extremities, the clip body bending at the recess when moving to the closed position, the first and second tissue layers being captured in the recess.