Soft-ended fibered micro vaso-occlusive devices

• US 5,976,162 A
• Filed: 03/13/1998
• Issued: 11/02/1999
• Est. Priority Date: 04/10/1996
• Status: Expired due to Term

• Current Assignee: Target Therapeutics, Inc. (Boston Scientific Corporation)
• Original Assignee: Target Therapeutics, Inc. (Boston Scientific Corporation)
• Inventors: Nguyen, Kim, Ho, Liem, Doan, Hong, Doan, Hanh, Gia, Son M.
• Primary Examiner(s): Jackson, Gary
• Application Number:
  US09/042,416
• Time in Patent Office: 599 Days
• Field of Search: 606/151, 606/213, 606/191, 606/198, 606/194, 606/200, 623/1, 623/11, 623/12, 623/13, 604/104, 128/831, 128/843
• US Class Current: 606/151
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12181 formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61M 2025/0081 Soft tip
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 25/008 Strength or flexibility characteristics of the catheter tip

Abstract

This is a micro-vaso-occlusive device intended generally for occlusion of small arteries located distally in the vasculature. The device is made up of a binder, often radio-opaque, which may be short in length by comparison to the length of the included thrombogenic fibers. The fibers form the other portion of the device. At least one end of the device includes a solid but comparatively soft end typically made of a molten mass of the fibers. The micro device may have multiple binder sections. The fibers may be straight, looped, or tufted.

Claims

1. A vaso-occlusive device comprising:

a.) at least one elongated retainer having opposing ends, a retainer axis extending between those ends, an axial length, at least one passageway extending along said axis;

b.) at least one fiber passing through at least a portion of said at least one passageway; and

c.) at least one soft tip situated at at least one of said retainer opposing ends.

2. The device of claim 1 wherein a soft tip is adherent to each of said retainer opposing ends.

3. The vaso-occlusive device of claim 2 wherein the soft tip is formed by the application of heat to melt said at least one fiber.

4. The vaso-occlusive device of claim 2 wherein the soft tip is formed by applying a material onto the tip region.

5. The vaso-occlusive device of claim 2 wherein the material applied to the tip region is selected from the group consisting of glues, epoxies, and polymers.

6. The device of claim 1 wherein the retainer is radio-opaque.

7. The device of claim 1 wherein the retainer comprises a material selected from the group consisting of stainless steel, gold, tungsten, platinum, palladium, rhodium, rhenium, and alloys thereof.

8. The device of claim 1 wherein the retainer comprises a polymeric material.

9. The device of claim 8 wherein the polymeric material comprises an epoxy.

10. The device of claim 1 wherein the retainer has a shape selected from spheroid, ovoid, and cylindrical.

11. The device of claim 1 wherein the retainer comprises a coil.

12. The device of claim 1 wherein the device comprises a multiplicity of retainers.

13. The device of claim 12 wherein a portion of the fibers terminate between at least two of said multiplicity of retainers.

14. The device of claim 12 wherein the multiplicity of fibers extend outwardly from the retainer axis between said at least two of said multiplicity of retainers.

15. The device of claim 1 wherein the retainer has an external region and wherein at least a portion of the exterior region is covered with a braided polymeric covering.

16. The device of claim 1 wherein the retainer has an external region and wherein at least a portion of the exterior region is covered with polymeric fibers.

17. The vaso-occlusive device of claim 1 wherein the multiplicity of fibers comprises a bundle.

18. The vaso-occlusive device of claim 1 wherein the ratio of retainer length to the retainer diameter is no more than about two.

19. The vaso-occlusive device of claim 1 the ratio of retainer length to the retainer diameter is no more than about one.

20. The vaso-occlusive device of claim 1 wherein the multiplicity of fibers has a length and wherein the ratio of the length of the fibers to the retainer length is at least two.

21. The vaso-occlusive device of claim 1 wherein the multiplicity of fibers has a length and wherein the ratio of the length of the fibers to the retainer length is at least five.

22. The vaso-occlusive device of claim 1, wherein the retainer has a diameter and the retainer diameter is between about 0.005 and about 0.015 inches.

23. The vaso-occlusive device of claim 1, wherein multiple passageways extend along the retainer axis.

24. A vaso-occlusive device comprising:

a.) at least one elongated helical coil having opposing ends, a retainer access between those ends, an axial length, a passageway extending along said access;

b.) a clip having a closed end and arms extending from that closed end, wherein the arms are passed through the retainer passageway from one opposing end to the other,

c.) at least one fiber retained within the closed end of the clip; and

d.) a soft tip situated at at least one of said helical coil opposing ends.

25. The device of claim 24 wherein the clip is held in place within the retainer coil by the soft tip.

26. The device of claim 24 wherein the retainer is radio-opaque.

27. The device of claim 24 wherein the retainer coil comprises of material selected from the group consisting of stainless steel, gold, tungsten, platinum, palladium, rhodium, rhenium and alloys thereof.