Method for respiratory tidal volume measurement
First Claim
1. A method of obtaining respiratory tidal volume information of an animal or human from a blood pressure signal indicative of sensed variations in blood pressure of the animal or human, the method comprising the steps of:
- signal processing, external from the animal or human, the blood pressure signal to develop an amplitude versus time waveform;
extracting from the developed amplitude versus time waveform a sequence of selected blood pressure features derived from individual cardiac cycles of the amplitude versus time waveform over a selected time interval;
fitting a mathematical model to the extracted sequence of selected blood pressure features to yield a fitted mathematical model;
characterizing changes in blood pressure that occur over a respiratory cycle from the fitted mathematical model; and
computing the respiratory tidal volume information as a function of the characterized changes in blood pressure.
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Abstract
A method obtains physiologic parameter information of an animal or human, such as respiratory tidal volume, from a blood pressure signal from an implanted blood pressure sensor in the animal or human. Specifically, the blood pressure signal is externally signal processed to develop an amplitude versus time waveform. A sequence of selected blood pressure features derived from individual cardiac cycles of the amplitude versus time waveform over a selected time interval are extracted from the developed amplitude versus time waveform. A mathematical model is fitted to the extracted sequence of selected blood pressure features to yield a fitted mathematical model. Blood pressure information indicative of a magnitude of the change in blood pressure that occurs over a respiratory cycle is computed from the fitted mathematical model. The physiologic parameter respiratory tidal volume, is then computed as a function of a correction factor and the blood pressure information.
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Citations
13 Claims
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1. A method of obtaining respiratory tidal volume information of an animal or human from a blood pressure signal indicative of sensed variations in blood pressure of the animal or human, the method comprising the steps of:
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signal processing, external from the animal or human, the blood pressure signal to develop an amplitude versus time waveform; extracting from the developed amplitude versus time waveform a sequence of selected blood pressure features derived from individual cardiac cycles of the amplitude versus time waveform over a selected time interval; fitting a mathematical model to the extracted sequence of selected blood pressure features to yield a fitted mathematical model; characterizing changes in blood pressure that occur over a respiratory cycle from the fitted mathematical model; and computing the respiratory tidal volume information as a function of the characterized changes in blood pressure. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification