Automatic pen-shaped syringe

• US 5,984,900 A
• Filed: 05/20/1994
• Issued: 11/16/1999
• Est. Priority Date: 11/29/1991
• Status: Expired due to Fees

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Mikkelsen, S.o slashed.ren
• Primary Examiner(s): STRIGHT, RONALD K
• Application Number:
  US08/256,883
• Time in Patent Office: 2,006 Days
• Field of Search: 604/232-234, 604/207-209, 604/135, 604/131, 604/136, 604/132-134, 604/117, 604/218, 604/137-139, 604/199, 604/220, 604/71, 604/72, 604/156, 604/157
• US Class Current: 604/208
• CPC Class Codes: A61M 2005/2488 via rotation, e.g. threads or bayonet
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/315 Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
• CPC Class Codes: A61M 5/31553 without axial movement of dose setting member
• CPC Class Codes: A61M 5/31591 Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion
• CPC Class Codes: A61M 5/5013 Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
• CPC Class Codes: A61M 5/502 for blocking the piston

Abstract

A pen shaped syringe with automatic needle insertion has an injection system integrally displaceable in a housing and comprising a basic part carrying a medicine reservoir with a hypodermic needle at its distal end, and a dosing mechanism with a carrier engaging a cogged piston rod, the carrier being coupled to a dose spindle in a rotatable but not displaceable way. The dose spindle is provided with a thread engaging a thread in a sequence part having protrusions engaging slots in the basic part to allow a limited axial movement of the parts in relation to each other, the extent of the movement being defined by the rotational position of the dose spindle. A spring is compressed between the basic part and the housing when the basic part is moved in the proximal direction by exerting a cocking force on the sequence part which part after having performed the set limited axial movement in relation to the basic part carries this basic part against the force of the spring.

Claims

1. A pen-shaped syringe which may be used for automatic insertion of a needle and subsequent injection of a set dose, said syringe comprising a housing having an axis and proximal and distal ends, and:

(a) a basic part which is axially displaceable in the housing;

(b) a medicine holding member, disposed in said housing, which is coupled to the basic part to follow axial movements of the basic part, which has a proximal end and a distal end, and which is designed to carry an injection needle at its distal end;

(c) a spring coupled between said basic part and said housing for urging said basic part towards the distal end of said housing;

(d) a piston rod provided with cogging, wherein said piston rod is axially movable within said housing and has a distal end adjacent the proximal end of said medicine holding member;

(e) a dose setting spindle having a distal end which is disposed in the housing and which is provided with an outer thread and a proximal end terminated by a button disposed outside of said housing for setting a dose, wherein said spindle is both rotatable about the housing axis and axially displaceable relative to the housing;

(f) a carrier disposed in said housing, which carrier is coupled to the dose setting spindle to follow axial movements of the spindle and which carrier engages the cogging of the piston rod in such a way that, when the carrier is moved in a proximal direction, the carrier slides over the cogging, and, when the carrier is moved in a distal direction, the carrier moves the piston rod with it; and

(g) a sequence part which is axially displaceable but non-rotatable in the housing, which sequence part has a proximal end with an internal thread engaging the outer thread of the dose setting spindle, such that rotation of the spindle, due to the non-rotatability of the sequence part, moves the sequence part in the axial direction;

wherein one of the said base and sequence parts includes an axially oriented slot having a terminal surface, and the other of the said base and sequence parts includes a first protrusion disposed in the slot for selectively engaging the terminal surface;

wherein a dose may be set by rotating the spindle such that the protrusion is moved a predetermined distance away from the terminal surface;

wherein the syringe may be cocked by moving the sequence part axially towards the proximal end of the housing, wherein initial movement of the sequence part causes the protrusion and the terminal surface to move towards one another without movement of the basic part in the housing, and wherein, after the protrusion engages the terminal surface, further movement of the sequence part moves the basic part, against the force of the spring, along with the holding member, in the proximal direction, which will retract a needle mounted on the holding member into the housing;

wherein, upon releasing the sequence part, the spring moves the basic part and, along with it, the holding member, sequence part, and spindle, towards the distal end of the housing, whereby a needle mounted on the holding member will protrude from the distal end of the housing; and

wherein the predetermined dose may then be administered by pushing the spindle in the distal direction.

2. A pen-shaped syringe according to claim 1, wherein the protrusion is provided on the sequence part, and the slot is provided in the basic part.

3. A pen-shaped syringe according to claim 2, further comprising a ramrod which is axially displaceable relative to the housing, wherein the ramrod includes a first portion which is accessible from outside the housing for moving the ramrod axially, and wherein the ramrod abuts the sequence part such that, when the ramrod is moved in a proximal direction, such movement is transmitted to the sequence part for moving the sequence part in a proximal direction.

4. A pen-shaped syringe according to claim 1, further comprising a trigger means supported by the housing which, after a predetermined axial movement of the sequence part in the proximal direction, prevents movement of the sequence part in a distal direction, and a trigger release which, when actuated, causes the trigger means to release the sequence part.