Ophthalmic surgical laser and method

• US 5,984,916 A
• Filed: 04/20/1993
• Issued: 11/16/1999
• Est. Priority Date: 04/20/1993
• Status: Expired due to Term

• Current Assignee: AMO Development LLC (Johnson & Johnson)
• Original Assignee: Shui T. Lai
• Inventors: Lai, Shui T.
• Primary Examiner(s): Shay, David M.
• Application Number:
  US08/051,033
• Time in Patent Office: 2,401 Days
• Field of Search: 606/2-19
• US Class Current: 606/11
• CPC Class Codes: A61B 2017/00172 Pulse trains, bursts, intermittent continuous operation
• CPC Class Codes: A61F 2009/00846 Eyetracking
• CPC Class Codes: A61F 2009/00863 Retina
• CPC Class Codes: A61F 2009/0087 Lens
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 2009/00874 Vitreous
• CPC Class Codes: A61F 2009/00889 Capsulotomy
• CPC Class Codes: A61F 9/00831 Transplantation
• CPC Class Codes: A61F 9/00834 Inlays; Onlays; Intraocular lenses [IOL]
• CPC Class Codes: B23K 26/0624 using ultrashort pulses, i.e. pulses of 1ns or less

Abstract

A laser-based method and apparatus for corneal and intraocular surgery. The preferred method of performing a surface ablation of cornea tissue or other organic materials uses a laser source which has the characteristics of providing a shallow ablation depth or region (about 0.2 μm to about 5.0 μm), a low ablation energy density threshold (about 0.2 to 5 μJ/(10 μm)²), and extremely short laser pulses (having a duration of about 0.01 picoseconds to about 2 picoseconds per pulse) to achieve precise control of tissue removal. The laser beam cross-sectional area is preferably about 10 μm in diameter. The preferred laser system includes a broad gain bandwidth laser, such as Ti₃ Al₂ O₃, Cr:LiSrAlF₆, Nd:YLF, or similar lasers, with a preferred wavelength of about 830 nm, which is generally transmissive in eye tissue. Various surgical procedures can be performed to correct refractive errors or to treat eye diseases. The invention can be used to excise or photoablate regions within the cornea, capsule, lens, vitreoretinal membrane, and other structures within the eye. The invention provides an improved method of eye surgery which has accurate control of tissue removal, flexibility of ablating tissue at any desired location with predetermined ablation depth, an optically smooth finished surface after the surgery, and a gentle surgical beam for laser ablation action.

Claims

1. A method for providing controlled ablation of organic material at a point of interaction by the steps of:

(1) generating laser pulses having an energy density of less than 5 μ

J/(10 μ

m)² and a duration in a range of about 0.01 picoseconds to less than 1 picosecond;

(2) applying the laser pulses to ablate organic material.

2. The method of claim 1, wherein the step of generating beam pulses includes generating at least one laser pulse having a wavelength transmissive in organic material.

3. The method of claim 1, wherein the step of generating beam pulses includes generating laser pulses emitted at a rate of up to approximately 100,000 pulses per second.

4. The method of claim 1, wherein the step of generating includes generating at least one laser pulse having been generated by a broad gain bandwidth laser.

5. The method of claim 1, including the further step of positioning the laser pulses within a selected portion of the material.

6. The method of claim 1, including the further step of determining the position of the laser pulses within the material.

7. The method of claim 1, including the further step of controlling the diameter of the cross sectional area of the laser pulses.

8. The method of claim 1, including the further step of determining the diameter of the cross sectional area of the laser pulses.

9. The method of claim 1, including the further step of controlling the intensity of the laser pulses.

10. The method of claim 1, including the further step of determining the intensity of the laser pulses.

11. The method of claim 1, including the further step of controllably blocking the laser pulses from the material.

12. The method of claim 1, wherein the step of generating beam pulses includes generating at least one laser pulse having a wavelength transmissive in eye tissue.

13. The method of claim 12, wherein the step of generating beam pulses includes generating laser pulses having a wavelength in one of the ranges of about 400 nm to about 1900 nm, about 2.1 to about 2.8 μ

m, or longer than about 3.1 μ

m.

14. The method of claim 1, including the further step of focusing the laser pulses at a selected interaction point in the material.

15. The method of claim 14, wherein the step of applying includes applying the laser pulses to a selected interaction point which has a diameter in the range of about 1 μ

m to about 30 μ

m.

16. A method for ablation of eye tissue by the steps of:

(1) generating laser pulses having an energy density of less than 5 μ

J/(10 μ

m)² and a duration in a range of about 0.01 picoseconds to less than 1 picosecond;

(2) applying the laser pulses to ablate eye tissue.

17. The method of claim 16, further including the steps of:

(1) positioning the laser pulses within a selected region of the eye tissue;

(2) controlling the diameter of the cross sectional area of the laser pulses;

(3) controlling the intensity of the laser pulses.

18. The method of claim 16, including the further step of controllably blocking the laser pulses from the eye tissue.

19. The method of claim 16, wherein the laser pulses have an undeflected position, and further including the step of generating a visible guide beam coaxial with the undeflected position of the laser pulses for aligning the laser pulses on an eye.

20. The method of claim 16, wherein the laser pulses have an undeflected position, further including the step of biasing the alignment of the undeflected position of the laser pulse with respect to the eye by tracking movement of the eye.

21. The method of claim 16, including the further step of using the laser pulses to make excisions on the exterior of the eye.

22. The method of claim 16, including the further step of using the laser pulses to make excisions within the interior of the eye.

23. The method of claim 16, including the further step of performing an ophthalmic surgical procedure for correcting myopia using the generated laser pulses, wherein the ophthalmic surgical procedure comprises the step of using the laser pulses to ablate an interior chamber beneath the central surface of the eye.

24. The method of claim 16, including the further step of performing an ophthalmic surgical procedure using the generated laser pulses, wherein the ophthalmic surgical procedure is selected from the group consisting of:

(1) radial keratotomy;

(2) creating transverse cuts in the cornea;

(3) creating straight line excisions in the cornea;

(4) creating curved-line excisions in the cornea;

(5) creating multiple radial cuts, equal or partially equal in excision length and with an angular separation between cuts, made on the cornea;

(6) creating a curved channel excision in the cornea;

(7) creating a point excision in the cornea;

(8) creating an interrupted line excision in the cornea;

(9) creating a curved excision of varying depth in the cornea;

(10) removing a geometric area from the cornea;

(11) creating a spiral excision in the cornea;

(12) creating holes in the posterior capsule of the eye;

(13) creating holes in the anterior capsule of the eye;

(14) creating holes in the iris;

(15) cutting vitreoretinal membranes;

(16) producing sculpted cornea caps in advance of need;

(17) sculpting the cornea according to a predetermined shape;

(18) removing cornea tissue in an annular ring around the center of the cornea;

(19) removing cornea tissue such that more tissue is removed at the center portion of the cornea, with a decreasing amount of tissue being removed towards the periphery of the cornea; and

(20) removing eye tissue.

25. The method of claim 16, including the further step of performing an ophthalmic surgical procedure for correcting hyperopia using the generated laser pulses, wherein the ophthalmic surgical procedure comprises the steps of:

(1) using the laser pulses to ablate an interior annular chamber beneath the central surface of the eye;

(2) using the laser pulses to make an annular excision near the periphery of the annular chamber to free an edge of the outer portion of the annular chamber from attachment to the eye.

26. The method of claim 25, wherein the ophthalmic surgical procedure comprises the further step of making perimeter radial cuts in the edge of the outer portion of the annular chamber.

27. A method of modifying the refractive power of the eye by the steps of:

(1) generating a laser beam comprising pulses having an energy density of less than 5 μ

J/(10 μ

m)² and a duration in a range of about 0.01 picoseconds to less than 1 picosecond;

(2) applying the laser beam to ablate cornea tissue.

28. The method of claim 27, including the further step of removing a geometric volume of eye tissue inside the stroma or the Bowman'"'"'s layer of the eye, thereby creating at least one cavity in the eye tissue.

29. The method of claim 28, including the further step of performing incisions of the cornea such that the portion of cornea locating above such cavities relaxes, collapsing the cavity such that the curvature of the eye at and near the optical axis of the eye is modified to attain a predetermined refractive power.

30. The method of claim 29, wherein the incisions are performed with either a laser or a mechanical instrument.

31. The method of claim 30, wherein the incisions consist of arcuate cuts shaped as predetermined arc lengths having a radius of curvature, positioned at predetermined locations from the visual axis of the eye.

32. The method of claim 30, wherein the incisions consist of radial cuts of predetermined lengths and depths, positioned at predetermined locations from the visual axis of the eye.

33. The method of claim 27, further including the steps of:

(1) applanating the cornea with an applanation plate such that (a) the location of the applanating plate provides a fixed three dimensional reference to the location of the laser beam, and (b) the shape of the cornea in contact with the applanation plate is conformed to a predetermined shape of the contact surface of the applanation plate;

(2) locating an interaction point of the laser beam inside the eye using the applanation plate as a location reference; and

(3) ablating eye tissue of a predetermined shape.

34. The method of claim 33, wherein the predetermined shape can be any of a line, a geometric area, or a geometric volume.

35. The method of claim 33, wherein the contact surface of the applanator plate can be any of plano, concave, or convex.

36. The method of claim 35, wherein the step of generating includes generating at least one laser pulse generated by a laser medium selected from one of the Ti³ :

Al₂ O₃, Cr;

LiSrAlF₆, and Nd;

YLF.