Transdermal hormone patch
First Claim
Patent Images
1. A transdermal therapeutic system which comprises;
- A. a backing film;
B. a coating on the backing film which comprises;
(i) an acrylate-based pressure-sensitive adhesive;
(ii) a hormone selected from the group consisting of oestrogen, androgen and gestagen; and
(iii) a resorption accelerator comprising a mixture of oleic acid and 2-(2-ethoxyethoxy)-ethanol wherein the mixture has been incorporated in an amount of 1 to 10 percent by weight of the system excluding the weight of the backing film plus the weight of the releasable protective film, and wherein the oleic acid and 2-(2-ethoxyethoxy)-ethanol have been incorporated with a ratio by weight of 2;
1 to 1;
2; and
C. a releasable protective film over the coating.
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Accused Products
Abstract
A transdermal therapeutic system (TTS) which contains as the active ingredients an oestrogen and a gestagen or a gestagen or androgen as well as an acrylate adhesive and, as resorption promoters, the two substances oleic acid and 2-(2-ethoxyethoxy)ethanol.
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Citations
8 Claims
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1. A transdermal therapeutic system which comprises;
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A. a backing film; B. a coating on the backing film which comprises; (i) an acrylate-based pressure-sensitive adhesive; (ii) a hormone selected from the group consisting of oestrogen, androgen and gestagen; and (iii) a resorption accelerator comprising a mixture of oleic acid and 2-(2-ethoxyethoxy)-ethanol wherein the mixture has been incorporated in an amount of 1 to 10 percent by weight of the system excluding the weight of the backing film plus the weight of the releasable protective film, and wherein the oleic acid and 2-(2-ethoxyethoxy)-ethanol have been incorporated with a ratio by weight of 2;
1 to 1;
2; andC. a releasable protective film over the coating. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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Specification