×

Method and apparatus for processing nucleic acids using a small temperature-changing zone

  • US 5,985,555 A
  • Filed: 09/19/1996
  • Issued: 11/16/1999
  • Est. Priority Date: 03/19/1994
  • Status: Expired due to Fees
First Claim
Patent Images

1. A method for rapid processing of nucleic acids in a reaction mixture, the method comprisingtemperature-regulating the reaction mixture by changing a temperature of a temperature-changing element to effect a temperature change in a temperature-changing zone which adjoins the temperature-changing element, while maintaining the remaining portion of the reaction mixture at essentially isothermal conditions throughout the temperature-regulating step, wherein the temperature-changing element has a surface which adjoins the temperature-changing zone, the temperature-changing zone is relatively small as compared to the entire reaction mixture and comprises an area less than 0.2 mm in length from the surface, and reagents capable of binding to the nucleic acids to be processed are bound to the surface.

View all claims
  • 2 Assignments
Timeline View
Assignment View
    ×
    ×