Antisense inhibition of interleukin-15 expression
First Claim
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1. An antisense compound 8 to 30 nucleobases in length targeted to a 5'"'"'UTR or a 3'"'"'UTR of a nucleic acid molecule encoding human Interleukin-15, wherein said antisense compound inhibits the expression of human Interleukin-15.
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Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of Interleukin-15. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Interleukin-15. Methods of using these compounds for modulation of Interleukin-15 expression and for treatment of diseases associated with expression of Interleukin-15 are provided.
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19 Claims
- 1. An antisense compound 8 to 30 nucleobases in length targeted to a 5'"'"'UTR or a 3'"'"'UTR of a nucleic acid molecule encoding human Interleukin-15, wherein said antisense compound inhibits the expression of human Interleukin-15.
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3. An antisense compound up to 30 nucleobases in length comprising SEQ ID NO:
- 8, 9, 10, 11, 13, 14, 15, 21, 22, 23, 25, 26, 28, 29, 30, 31, 32, 33, 35, 36, 37, 39, 42, 44 or 46.
- View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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