Triple antimicrobial composition

• US 5,985,931 A
• Filed: 06/02/1998
• Issued: 11/16/1999
• Est. Priority Date: 11/13/1995
• Status: Expired due to Fees

• Current Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Original Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Inventors: Modak, Shanta, Sampath, Lester
• Primary Examiner(s): Weddington, Kevin E.
• Application Number:
  US09/011,841
• Time in Patent Office: 532 Days
• Field of Search: 514/634, 514/635
• US Class Current: 514/634
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/30 characterised by the surfactants
• CPC Class Codes: A01N 31/02 Acyclic compounds
• CPC Class Codes: A01N 31/08 Oxygen or sulfur directly attached to an aromatic ring system
• CPC Class Codes: A01N 33/12 Quaternary ammonium compounds
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof

Abstract

The present invention relates to antimicrobial compositons comprising (i) less than or equal to two percent by weight chlorhexidine or chlorhexidine salt; (ii) less than or equal to 1 percent by weight of a quaternary ammonium compound, such as benzalkonium chloride; and (iii) less than or equal to two percent by weight of parachlorometaxylenol. The antimicrobial compositions of the invention may be utilized in antimicrobial deterents, soaps, creams rinses, and emulsions for use in the medical community as well as general public use.

Claims

1. An antimicrobial composition comprising

(i) greater than zero and less than or equal to two percent of polyhexamethylene biguanide;

(ii) greater than zero and less than or equal to 0.1 percent of a quaternary ammonium compound; and

(iii) greater than zero and less than or equal to two percent parachlorometaxylenol;

wherein the combination of (i), (ii) and (iii) exhibits effective antimicrobial activity.

2. The composition of claim 1 wherein the amount of polyhexamethylene biguanide is about 0.025-0.1 percent.