Diagnostic complex for measurement of the condition of biological tissues and liquids
First Claim
1. An apparatus for simultaneously obtaining a biological sample and measuring the electrical resistance of said sample at at least two different frequencies for diagnosis of a condition of said sample, comprising:
- a. a main case, said main case comprising a tube and demountable handle;
b. an aspirating needle at least partially inside said tube, for obtaining a sample of biological liquid and for serving as an active electrode in contact with said biological sample;
c. a liquid collector connected to said aspirating needle to receive said sample of said biological liquid, said liquid collector comprising a metal conductor in electrical contact with said needle and a metal piston, wherein at the determination of said condition of said biological liquid said needle executes the role of active electrode, and said metal piston executes the role of passive electrode; and
d. an electroimpedancemeter electrically connected to said active and passive electrodes, for simultaneous measurement of said electrical resistance of the sample at at least two different frequencies.
1 Assignment
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Accused Products
Abstract
An apparatus and method for simultaneously obtaining a sample of biological tissue or liquid and measuring the electrical resistance at at least two different frequencies, or dispersion of resistance, of the biological tissue or liquid for the purpose of diagnosis of the condition of the tissue or liquid. The apparatus of the invention includes a main case, which includes a tube and demountable handle; a hook for obtaining a sample of biological tissue and for serving as a passive electrode in contact with the biological tissue; an aspirating needle for obtaining a sample of biological liquid and for serving as an active electrode in contact with the biological liquid or tissue; a liquid collector, which includes a metal conductor in contact with the biological liquid and piston for obtaining a sample of biological liquid and providing an electrode for resistance measurements; a electrical plug allowing electrical connection between the electrodes and an electroimpedancemeter. The electroimpedancemeter provides for simultaneous measurement of electrical resistance at at least two different frequencies. An apparatus and method for using the apparatus comprising a flexible electrode probe and an electroimpedancemeter are also provided. A method is also provided for comparative diagnosis of the condition of two biological liquids, from a comparison of electrical resistance measurements.
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Citations
47 Claims
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1. An apparatus for simultaneously obtaining a biological sample and measuring the electrical resistance of said sample at at least two different frequencies for diagnosis of a condition of said sample, comprising:
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a. a main case, said main case comprising a tube and demountable handle; b. an aspirating needle at least partially inside said tube, for obtaining a sample of biological liquid and for serving as an active electrode in contact with said biological sample; c. a liquid collector connected to said aspirating needle to receive said sample of said biological liquid, said liquid collector comprising a metal conductor in electrical contact with said needle and a metal piston, wherein at the determination of said condition of said biological liquid said needle executes the role of active electrode, and said metal piston executes the role of passive electrode; and d. an electroimpedancemeter electrically connected to said active and passive electrodes, for simultaneous measurement of said electrical resistance of the sample at at least two different frequencies. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
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30. A method for simultaneously obtaining a biological sample and measuring electrical resistance of said sample at at least two different frequencies for the purpose of diagnosis of a condition of the sample comprising the steps of:
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a. inserting an aspirating needle into a biological liquid; c. withdrawing a sample of said biological liquid with said aspirating needle and into a syringe, thereby contacting said biological liquid with an active and a passive electrode provided to said syringe; d. moving said tube out of said biological liquid; and e. measuring in said syringe, said electrical resistance of said sample of said biological liquid at at least two different frequencies with said active and passive electrodes electrically connected to an electroimpedancemeter. - View Dependent Claims (31, 32, 33, 34, 35, 36, 37)
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38. An apparatus for simultaneously obtaining a sample of mammalian biological tissue or liquid and measuring the electrical resistance of said tissue or liquid at at least two different frequencies for diagnosis of a condition of said tissue or liquid, comprising:
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a. a main case, comprising a tube and demountable handle, said tube being insertable at one end into said demountable handle of gun or other type, said tube comprising corrosion-proof medical steel or other conventional material suitable for medical diagnostic use, said tube having at least one hole at one end; b. a protective casing which fits over said tube, is demountable and comprises a ring and spring-ball for fixing the spring-ball location of said casing at said hole, said location representing a maximum forward position or maximum reverse position of said casing; c. a hook comprising a pointed end, fixed at one end of said tube away from said handle and extending from said end for obtaining a sample of said biological tissue and for serving as a passive electrode in contact with said biological tissue; d. an aspirating needle, located inside said tube, the distal end of said needle extending from the end of said tube away from said handle, for obtaining a sample of said biological liquid and for serving as an active electrode in contact with said biological liquid or tissue, the proximal end of said needle being finished by a metal flange inside said main case handle; e. a metal-glass syringe connected to the metal flange of the needle to receive said sample of said biological liquid, said syringe comprising a glass flask, metal conic tip and metal piston, wherein at the determination of a condition of said biological liquid said metal tip or said needle, when electrically connected to said metal tip, executes a role of active electrode, and said metal piston executes a role of passive electrode; f. a fixing unit, located inside said tube and serving simultaneously to fix said hook at one end of said tube away from said handle and to isolate the area of said biological tissue or liquid; g. an electroimpedancemeter electrically connected to said active and passive electrodes, for simultaneous measurement of complete electrical resistance at two different frequencies; and h. an electrical plug, located in said handle and connected by electrical leads with each of said active and passive electrodes, said electrical plug allowing electrical connection between said electroimpedancemeter and said active and passive electrodes. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47)
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Specification