Cardiac flow sensor

• US 5,989,192 A
• Filed: 09/25/1997
• Issued: 11/23/1999
• Est. Priority Date: 09/25/1997
• Status: Expired due to Term

• Current Assignee: Michael J. Jaro
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Weijand, Koen J., Schouten, Vincent J. A.
• Primary Examiner(s): Nasser, Robert L.
• Application Number:
  US08/937,442
• Time in Patent Office: 789 Days
• Field of Search: 600/504, 600/505, 600/526, 600/549
• US Class Current: 600/504
• CPC Class Codes: A61B 5/028 by thermo-dilution
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control

Abstract

Apparatus and method are provided for obtaining a measure of blood flow, and more specifically cardiac output, by analyzing blood temperature variations in the arterial tract. In a first embodiment, a lead carrying two closely spaced temperature sensors is positioned so that the sensors are in the atrial tract and produce temperature signals representative of small cyclical temperature variations of the blood outputted from the heart. The two signals have substantially similar patterns for each cardiac cycle, but the signals are separated by a short time (.increment.T) representative of the distance between the two sensors. The patterns are correlated to find .increment.T, from which cardiac output is calculated. In an alternate embodiment, a single blood temperature sensor is employed along with a sensor for determining cardiac contractions, and a measure of cardiac output is obtained by comparing the time difference between a feature of the blood temperature signal with the time of cardiac contraction.

Claims

1. A system for determining a measure of arterial blood flow from the heart, comprising:

a sensor lead having thereon a pair of fast time response temperature sensors positioned a short distance apart on said lead, said lead having output terminals and conducting means for conducting said temperature signals from each of said sensors to respective ones of said output terminals;

processing means for receiving said signals from said output terminals and for processing same to derive sets of digital representations of each of said temperature signals;

correlation means for finding the time delay between said two temperature signals at which said signals optimally correlate; and

computational means for computing from said time delay a measure of blood flow.

2. The system as described in claim 1, comprising output means for determining a measure of cardiac output from said blood flow measure.

3. The system as described in claim 1, comprising EKG means for obtaining cardiac signals representative of cardiac electrical activity, and wherein said processing means comprises cyclical means triggered by said cardiac signals for deriving said digital representations corresponding to respective cardiac cycles.

4. The system as described in claim 3, wherein said correlation means comprises means for performing a correlation in the frequency domain on each set of digital representations for each cardiac cycle.

5. The system as described in claim 1, wherein said sensors are positioned apart by a distance no greater than 2 cm.

6. The system as described in claim 1, where each of said sensors has a time response of less than 100 ms.

7. A method of determining cardiac output of a patient, comprising:

positioning first and second fast response sensors in the patient'"'"'s arterial tract, said sensors being positioned a short distance from each other along the axis of the atrial tract;

obtaining naturally occurring cyclical temperature signals from each of said sensors corresponding to respective cardiac cycles;

processing said cyclical signals to obtain therefrom a measure of flow rate; and

determining cardiac output from said flow rate measure.

8. The method as described in claim 7, comprising performing correlation operations on pairs of said cyclical temperature signals.

9. The method as described in claim 7, comprising fixing said short distance in a range of about 1 mm to no more than 2 cm.

10. The method as described in claim 7, comprising obtaining cardiac electrical signals, and using said cardiac electrical signals to initiate said cyclical temperature signals.

11. A cardiac flow measurement system, comprising:

sensor means for providing cyclical signals representative of naturally occurring blood temperature variations of blood in the patient'"'"'s arterial tract; and

processing means for processing said signals to obtain a measure of blood flow from the patient'"'"'s heart.

12. The system as described in claim 11, wherein said sensor means comprises at least two fast time response sensors.

13. The system as described in claim 12, wherein said sensor means comprises lead means for carrying said two sensors at a fixed distance from each other no greater than about 2 cm.

14. The system as described in claim 13, wherein said processing means comprises correlation means for providing an indication of the time differential between the two signals from said two sensors.

15. The system as described in claim 14, wherein said sensors have time responses of less than 100 ms.