Method and apparatus for detecting ocular disease and abnormalities

• US 5,989,194 A
• Filed: 02/09/1998
• Issued: 11/23/1999
• Est. Priority Date: 02/09/1998
• Status: Expired due to Term

• Current Assignee: iScreen Vision, Inc., The United States of America As Represented By The Secretary of Agriculture
• Original Assignee: United States Of America As Represented By The Secretary Of The Army (Government of the United States of America), Vision Partners, LP
• Inventors: Bellows, Jack R., Davenport, Wayne E.
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US09/020,977
• Time in Patent Office: 652 Days
• Field of Search: 600/558, 351/211, 351/221
• US Class Current: 600/558
• CPC Class Codes: A61B 3/14 Arrangements specially adapted for eye photography apparatus or arrangements for taking photographs per se G03B

Abstract

A detection device for detecting ocular disease and abnormalities in humanyes. The ocular disease and abnormality detection device includes a photo-imaging device having a lens aligned on a selected optical axis. A flash unit generates a flash beam of light generally along the optical axis to produce retinal reflections from a patient'"'"'s eyes. The retinal reflections from the patient'"'"'s eyes are recorded by the photo-imaging device and displayed on a video display screen. A beamsplitter is positioned on the optical axis to pass the flash beam of light from the flash device to the patient'"'"'s eyes, and to pass the retinal reflection from the patient'"'"'s eyes to the photo-imaging device. A visual image is projected on a surface of the beamsplitter which appears to the patient'"'"'s eyes as being positioned on the optical axis and generally superimposed on the lens of the photo-imaging device. The patient'"'"'s eyes generally focus on the lens of the photo-imaging device as the patient views the projected image. A separate camera and video display is provided to monitor the patient'"'"'s face. Patient information is preferably recorded with the retinal reflections from the patient'"'"'s eyes. Methods of detecting ocular disease and abnormalities are also disclosed.

Claims

1. Apparatus for detecting ocular disease and abnormalities, comprising:

a headrest for supporting a patient'"'"'s head and aligning the patient'"'"'s eyes on a selected optical axis;

a photo-imaging device having a lens aligned on said selected optical axis, said lens being spaced from said headrest a predetermined focal distance and operable to receive a retinal reflection from the patient'"'"'s eyes;

a flash unit for generating a flash beam of light generally along said selected optical axis and producing retinal reflections from the patient'"'"'s eyes;

a beamsplitter positioned on said selected optical axis, said beamsplitter being operable to pass the flash beam of light from the flash unit to the patient'"'"'s eyes, and to pass the retinal reflections from the patient'"'"'s eyes to the lens of said photo-imaging device; and

a visual stimulus generator operable to project a visual image on a surface of said beamsplitter, said projected visual image appearing to the patient'"'"'s eyes as being aligned on said selected optical axis and generally superimposed on the lens of said photo-imaging device at said predetermined focal distance whereby the patient'"'"'s eyes generally focus on the lens of said photo-imaging device while viewing the projected visual image to permit accurate retinal reflections from the patient'"'"'s eyes to be recorded by said photo-imaging device.

2. The apparatus of claim 1 wherein said photo-imaging device comprises a digital camera for electronically recording the retinal reflections from the patient'"'"'s eyes.

3. The apparatus of claim 2 further comprising:

a data processing unit coupled to said digital camera for receiving and storing the electronically recorded retinal reflections from the patient'"'"'s eyes; and

a video display screen coupled to said data processing unit for displaying the recorded retinal reflections of the patient'"'"'s eyes.

4. The apparatus of claim 1 wherein said visual stimulus generator comprises;

a video cassette player operable to generate a moving visual image; and

a video display screen coupled to said video cassette player for projecting the moving visual image on the surface of said beamsplitter.

5. The apparatus of claim 1 wherein said visual stimulus generator is operable to vary the brightness of the projected visual image whereby pupil dilation of the patient'"'"'s eyes may be adjusted by increasing or decreasing the brightness of the projected visual image.

6. The apparatus of claim 1 wherein said flash unit is adjustable relative to said selected optical axis to provide adjustable angular separation between the flash beam of light and said selected optical axis.

7. The apparatus of claim 6 wherein the angular separation between the flash beam of light and said selected optical axis is adjustable in a range from about 1°

to about 5°

.

8. The apparatus of claim 1 further comprising:

an illumination source for illuminating the face of the patient while the patient'"'"'s head is positioned in the headrest;

a video camera positioned off the optical axis and operable to view the patient'"'"'s face; and

a video display screen coupled to the video camera for displaying a real-time image of the patient'"'"'s face.

9. The apparatus of claim 8 wherein said illumination source comprises an infrared light source.

10. The apparatus of claim 1 further comprising a video display screen positioned adjacent the headrest for displaying selected patient information whereby the patient information is recorded by said photo-imaging device with retinal reflections from the patient'"'"'s eyes.

11. The apparatus of claim 3 further comprising a data entry device coupled to said data processing unit for entering selected patient information whereby the patient information is stored and displayed with the recorded retinal reflections of the patient'"'"'s eyes.

12. Apparatus for detecting ocular disease and abnormalities, comprising:

a headrest for supporting a patient'"'"'s head and aligning the patient'"'"'s eyes on a selected optical axis;

a photo-imaging device having a lens aligned on said selected optical axis, said lens being spaced from said headrest a predetermined focal distance and facing toward said headrest for receiving a retinal reflection from the patient'"'"'s eyes;

a flash device positioned off the optical axis for generating a flash beam of light in a direction generally perpendicular to the optical axis;

a prism associated with said flash device for aligning the flash beam of light generally along said selected optical axis whereby the flash beam of light produces retinal reflections from the patient'"'"'s eyes;

a beamsplitter positioned on said selected optical axis intermediate said photo-imaging device and said headrest, said beamsplitter being operable to pass the flash beam of light from the flash device to the patient'"'"'s eyes, and to pass the retinal reflections from the patient'"'"'s eyes to the lens of said photo-imaging device; and

a visual stimulus generator positioned off said selected optical axis and operable to project a visual image on a surface of said beamsplitter, said projected visual image appearing to the patient'"'"'s eyes as being aligned on said selected optical axis and generally superimposed on the lens of said photo-imaging device at said predetermined focal distance whereby the patient'"'"'s eyes generally focus on the lens of said photo-imaging device while viewing the projected visual image to permit accurate retinal reflections from the patient'"'"'s eyes to be recorded by said photo-imaging device.

13. The apparatus of claim 12 wherein said photo-imaging device comprises a digital camera for electronically recording the retinal reflections from the patient'"'"'s eyes.

14. The apparatus of claim 13 further comprising:

a data processing unit coupled to said digital camera for receiving and storing the electronically recorded retinal reflections from the patient'"'"'s eyes; and

a video display screen coupled to said data processing unit for displaying the recorded retinal reflections of the patient'"'"'s eyes.

15. The apparatus of claim 12 wherein said visual stimulus generator comprises;

a video cassette player operable to generate a moving visual image; and

a video display screen coupled to said video cassette player for projecting the moving visual image on the surface of said beamsplitter.

16. The apparatus of claim 12 further comprising:

an illumination source for illuminating the face of the patient while the patient'"'"'s head is positioned in the headrest;

a video camera positioned off said selected optical axis and operable to view the patient'"'"'s face; and

a video display screen coupled to the video camera for displaying a real-time image of the patient'"'"'s face.

17. Apparatus for detecting ocular disease and abnormalities, comprising:

a headrest for supporting a patient'"'"'s head and aligning the patient'"'"'s eyes on a selected optical axis;

a digital camera having a lens aligned on said selected optical axis, said lens being spaced from said headrest a predetermined focal distance and operable to receive a retinal reflection from the patient'"'"'s eyes;

a flash unit for generating a flash beam of light generally along said selected optical axis and producing retinal reflections from the patient'"'"'s eyes which are electronically recorded by the digital camera;

an illumination source for illuminating the face of the patient while the patient'"'"'s head is positioned in the headrest;

a video camera operable to view the patient'"'"'s face;

a video display screen coupled to the video camera for displaying a real-time image of the patient'"'"'s face;

a beamsplitter positioned on said selected optical axis, said beamsplitter being operable to pass the flash beam of light from the flash unit to the patient'"'"'s eyes, and to pass the retinal reflections from the patient'"'"'s eyes to the lens of said digital camera; and

a visual stimulus generator operable to project a visual image on a surface of said beamsplitter, said projected visual image appearing to the patient'"'"'s eyes as being aligned on said selected optical axis and generally superimposed on the lens of said digital camera at said predetermined focal distance whereby the patient'"'"'s eyes generally focus on the lens of said digital camera while viewing the projected visual image to permit accurate retinal reflections from the patient'"'"'s eyes to be recorded by said digital camera.

18. The apparatus of claim 17 further comprising:

a data processing unit coupled to said digital camera for receiving and storing the electronically recorded retinal reflections from the patient'"'"'s eyes; and

a video display screen coupled to said data processing unit for displaying the recorded retinal reflections of the patient'"'"'s eyes.

19. The apparatus of claim 17 wherein said visual stimulus generator comprises;

a video cassette player operable to generate a moving visual image; and

a video display screen coupled to said video cassette player for projecting the moving visual image on the surface of said beamsplitter.

20. The apparatus of claim 19 wherein said illumination source comprises an infrared light source.

21. A method of detecting ocular disease and abnormalities, comprising:

aligning eyes of a patient on a selected optical axis;

aligning a lens of a photo-imaging device on said selected optical axis;

spacing the lens of the photo-imaging device from the patient'"'"'s eyes a predetermined focal distance;

directing a flash beam of light generally along said selected optical axis to produce retinal reflections from the patient'"'"'s eyes;

providing a beamsplitter on said selected optical axis, the beamsplitter being operable to pass the flash beam of light to the patient'"'"'s eyes, and to pass the retinal reflections from the patient'"'"'s eyes to the lens of the photo-imaging device;

projecting a visual image on the beamsplitter whereby the projected visual image appears to the patient'"'"'s eyes as being aligned on said selected optical axis and generally superimposed on the lens of the photo-imaging device at said predetermined focal distance, and whereby the patient'"'"'s eyes generally focus on the lens of the photo-imaging device while viewing the projected visual image; and

recording retinal reflections from the patient'"'"'s eyes with the photo-imaging device.

22. The method of claim 21 further comprising displaying the recorded retinal reflections from the patient'"'"'s eyes on a video display screen.

23. The method of claim 21 further comprising:

illuminating the patient'"'"'s face while the eyes of the patient are aligned on said selected optical axis;

viewing the patient'"'"'s face; and

displaying a real-time image of the patient'"'"'s face on a video display screen.

24. The method of claim 21 further comprising linking selected patient information with the recorded retinal reflections from the patient'"'"'s eyes.

25. A method of detecting ocular disease and abnormalities, comprising:

aligning eyes of a patient on a selected optical axis;

aligning a lens of a digital camera on said selected optical axis;

spacing the lens of the digital camera from the patient'"'"'s eyes a predetermined focal distance;

directing a flash beam of light generally along said selected optical axis to produce retinal reflections from the patient'"'"'s eyes;

providing a beamsplitter on said selected optical axis, the beamsplitter being operable to pass the flash beam of light to the patient'"'"'s eyes, and to pass the reflections from the patient'"'"'s eyes to the lens of the digital camera;

projecting a visual image on the beamsplitter whereby the projected visual image appears to the patient'"'"'s eyes as being aligned on said selected optical axis and generally superimposed on the lens of the digital camera at said predetermined focal distance, and whereby the patient'"'"'s eyes generally focus on the lens of the digital camera while viewing the projected visual image; and

electronically recording retinal reflections from the patient'"'"'s eyes with the digital camera.

26. Apparatus for detecting ocular disease and abnormalities, comprising:

a headrest for supporting a patient'"'"'s head and aligning the patient'"'"'s eyes on a selected optical axis;

a photo-imaging device having a lens aligned on said selected optical axis, said lens being spaced from said headrest a predetermined focal distance and operable to receive a retinal reflection from the patient'"'"'s eyes;

a flash unit for generating a flash beam of light generally along said selected optical axis and producing retinal reflections from the patient'"'"'s eyes;

a beamsplitter positioned on said selected optical axis, said beamsplitter being operable to pass the retinal reflections from the patient'"'"'s eyes to the lens of said photo-imaging device; and

a visual stimulus generator operable to project a visual image on a surface of said beamsplitter, said projected visual image appearing to the patient'"'"'s eyes as being aligned on said selected optical axis and generally superimposed on the lens of said photo-imaging device at said predetermined focal distance whereby the patient'"'"'s eyes generally focus on the lens of said photo-imaging device while viewing the projected visual image to permit accurate retinal reflections from the patient'"'"'s eyes to be recorded by said photo-imaging device.