Arrangement in electronically controlled injection devices

• US 5,989,221 A
• Filed: 04/15/1998
• Issued: 11/23/1999
• Est. Priority Date: 10/20/1995
• Status: Expired due to Fees

• Current Assignee: Pharmacia AB (Pharmacia Corp.)
• Original Assignee: Pharmacia & Upjohn AB (Pharmacia Corp.)
• Inventors: Hjertman, Birger
• Primary Examiner(s): Smith, Jeffrey A.
• Assistant Examiner(s): Robert, Eduardo C.
• Application Number:
  US09/060,052
• Time in Patent Office: 587 Days
• Field of Search: 604/131, 604/151, 604/152, 604/154, 604/141, 128/DIG. 1, 128/DIG. 12, 128/DIG. 13
• US Class Current: 604/131
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/60 with identification means
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/32 Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001

Abstract

In an electronically controlled injection device for the administering of one or more injections from an injection cartridge, the readying of the device for administering and the subsequent administering therefrom are controlled by an electronic control unit. This control unit comprises a position or attitude sensor which transmits signals to the control unit such that the readying of the device optionally cannot take place unless the longitudinal axis of the injection cartridge is oriented in a predetermined direction.

Claims

1. An injection device comprising:

a holder device;

an injection cartridge arranged in the holder device and having a rear end;

a piston provided at the rear end of the injection cartridge and displaceable forwards by a piston rod;

an electronic control unit for at least one of controlling a readying of the device for administering of at least one injection from said injection cartridge after positioning of said injection cartridge and controlling an administering therefrom, said control unit including a position sensor which emits position signals for governing said control unit so that during the readying of the device, forward movement of said piston rod is possible only when a longitudinal axis of said injection cartridge is substantially oriented in a predetermined direction, said control unit deactivating said position sensor or disregarding the position signals therefrom, after the readying of the device.

2. An injection device according to claim 1, further comprising an electric motor, which is controlled by said control unit, effecting movement of said piston rod.

3. An injection device according to claim 1, characterized in that said cartridge is a multi-chamber cartridge and in that said readying also comprises a reconstitution of an injectable composition.

4. An injection device according to claim 3, characterized in that said readying of the device is possible only with the longitudinal axis of the injection cartridge in an essentially vertical orientation, with the front end of the cartridge pointing downwards.

5. An injection device according to claim 3, characterized in that said readying of the device is possible only with the longitudinal axis of the cartridge in an essentially vertical orientation with its front end, from which the administering is to take place, pointing upward.

6. A portable or hand-held injection device comprising a container for a preparation, or components for a preparation, an outlet for the preparation and displacing means at least able to disolace the preparation through the outlet, characterized in that the device further comprises a position sensor designed to emit one or more position signals during readying of the devise indicative of an orientation of the container or component and a control unit designed to receive the position signals and to issue one or more operation signals for the device, the operation signals being at least one of one or more messages and one or more control signals for the displacing means, said control unit deactivating said position sensor or disregarding the position signals therefrom after the readying of the device.

7. The device of claim 6, characterized in that the container may contain gas and that the operation signals are designed to prevent displacing means activation when device orientation is in first predetermined positions unsuitable for deaeration and to allow displacing means activation when device orientation is in second predetermined positions suitable for deaeration.

8. The device of claim 6, characterized in that the container comprises at least two compartments for components of the preparation, that the displacing means are operative to mix contents of at least two compartments and that the operation signals are designed to prevent displacing means activation when device orientation is in first predetermined positions unsuitable for mixing and to allow displacing means activation when device orientation is in second predetermined positions suitable for mixing.

9. The device of claim 8, characterized in that the container is a dual or multi-chamber cartridge with at least one movable piston separating the compartments and a by-pass section for overflow of compartment content past the piston.

10. The device of claim 9, characterized in that the outlet points substantially vertically, in operation.

11. The device of claim 6, characterized in that the control unit is designed to register a change in position sensor signals.

12. The device of claim 11, characterized in that the operation signals are designed to prevent repeated displacing means activation for ejection of preparation through the outlet unless the device has been turned in a predetermined manner between the repeated displacement means activations.

13. The device of claim 11, characterized in that the operation signals are designed to prevent displacing means activation for ejection of preparation through the outlet unless the device has been turned in a predetermined manner.

14. The device of claim 6, characterized in that the operation signals are designed to prevent displacing means activation for ejection of preparation through the outlet when device orientation is in first predetermined positions unsuitable for administration and to allow displacing means activation for ejection of preparation through the outlet when device orientation is in second predetermined positions suitable for administration.

15. The device of claim 6 characterized in that the one or more operation signals are at least one of one or more messages and one or more control signals for the displacing means.

16. The device of claim 15, characterized in that the displacing means incorporates arming means, valve means or fluid control means and that the one or more operation signals are one or more control signals for said arming means, valve means, or fluid control means.

17. The device of claim 15, characterized in that the messages are one or more alarms or instructions detectable by an operator, for guidance of the operator to the actions stated.

18. The device of any one of claims 15, characterized in that the displacing means are activated by actuating means and that the one or more operation signals are one or more control signals for the actuating means.

19. The device of claim 18, characterized in that the actuating means comprises electric motor means for the displacing means.

20. An injection device comprising:

a multi-chamber injection cartridge including a rear piston having a pressure-sensitive gas relief valve;

a position sensor detecting an orientation of a longitudinal axis of said injection cartridge;

a piston rod provided at a rear end of said injection cartridge and communicating with said rear piston, responsive directly or indirectly to said position sensor, wherein said piston rod is displace able forwards during injection readying only when the position sensor detects the orientation to be substantially in a predetermined direction, wherein overpressure generated, prior to injection administration, in said injection cartridge by displacement of said piston rod is reduced via said pressure-sensitive valve.

21. The injection device according to claim 20, further comprising a control unit receiving position signals from said position sensor and controlling said piston rod, said control unit deactivating said position sensor or disregarding the position signals therefrom after the readying of the device.