Microchannel system for fluid delivery

• US 5,989,445 A
• Filed: 06/17/1998
• Issued: 11/23/1999
• Est. Priority Date: 06/09/1995
• Status: Expired due to Term

• Current Assignee: Board of Regents of the University of Michigan (University of Michigan)
• Original Assignee: Board of Regents of the University of Michigan (University of Michigan)
• Inventors: Chen, Jingkuang, Wise, Kensall D.
• Primary Examiner(s): Breneman, Bruce
• Assistant Examiner(s): Powell, Alva C
• Application Number:
  US09/098,695
• Time in Patent Office: 524 Days
• Field of Search: 216/2, 216/62, 216/87, 216/39, 216/56, 216/27, 438/719, 438/734, 438/735, 438/753
• US Class Current: 216/62
• CPC Class Codes: A61M 5/32 Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001
• CPC Class Codes: A61M 5/3291 Shafts with additional lateral openings
• CPC Class Codes: B41J 2/1601 Production of bubble jet print heads B41J2/1606, B41J2/162 take precedence
• CPC Class Codes: B41J 2/1628 dry etching
• CPC Class Codes: B41J 2/1631 photolithography
• CPC Class Codes: Y10S 239/19 Nozzle materials
• CPC Class Codes: Y10S 366/01 Micromixers: continuous laminar flow with laminar boundary mixing in the linear direction parallel to the fluid propagation with or without conduit geometry influences from the pathway

Abstract

Microchannels for conducting and expelling a fluid are embedded in a surface of a silicon substrate. A channel seal is made of plural cross structures formed integrally with the silicon substrate. The cross structures are arranged sequentially over each channel, each cross structure having a chevron shape. The microchannel is sealed by oxidizing at least partially the cross structures, whereby the spaces therebetween are filled. A dielectric seal which overlies the thermally oxidized cross structures forms a complete seal and a substantially planar top surface to the silicon substrate. The dielectric seal is formed of a low pressure chemical vapor deposition (LPCVD) dielectric layer. The channel is useful in the production of an ink jet print in head, and has a polysilicon heater overlying the dielectric seal. A current passing through the heater causes a corresponding increase in the temperature of the ink in the microchannel, causing same to be expelled therefreom. After expulsion of the fluid, the microchannel is refilled by capillary action. Control circuitry, including bonding pads and sensors, can be formed integrally on the silicon substrate. In drug or chemical delivery systems, sensors and/or stimulation circuitry for sensing or inducing neural and other response can be formed directly in the silicon substrate which contains the microchannel. The sensor is disposed in close proximity to the chemical distribution nozzle, facilitating neural and other studies. Microvalve arrangements can be formed with the microchannel, controlled by the on-chip circuitry.

Claims

1. A method of forming a microchannel nozzle, the method comprising the steps of:

performing a boron diffusion to form a boron-doped layer on the surface of a silicon wafer;

first etching the boron-doped layer on the surface of a silicon wafer to form a plurality of sequential structures;

second etching beneath the sequential structures to form a longitudinal channel thereunder; and

first sealing the longitudinal channel by thermally oxidizing the sequential structures, whereby oxidized silicon reduces the size of the spaces between the sequential structures.

2. The method of claim 1, wherein said step of performing a boron diffusion is performed on a p-type silicon wafer.

3. The method of claim 1, wherein said step of performing a boron diffusion is performed to form a highly doped boron diffusion having a thickness of approximately 3 μ

m on a p-type silicon wafer.

4. The method of claim 1, wherein said step of first etching comprises the step of performing a reactive ion etch.

5. The method of claim 1, wherein said step of first etching comprises the step of forming a plurality of sequential structures arranged diagonal with respect to said longitudinal channel.

6. The method of claim 1, wherein said step of second etching comprises the step of performing an anisotropic silicon etch.

7. The method of claim 1, wherein, after performing said step of second etching, there is provided the further step of boron diffusing the longitudinal channel.

8. The method of claim 1, wherein there is further provided the step of second sealing the longitudinal channel by depositing a dielectric layer over the oxidized sequential structures.

9. The method of claim 8, wherein said step of second sealing comprises the step of depositing a LPCVD dielectric layer over the oxidized sequential structures.

10. The microchannel nozzle arrangement of claim 1, wherein said channel seal is formed of a thermally conductive material.

11. The method of claim 1, wherein there is further provided the step of forming a fluid reservoir in the silicon wafer.

12. The method of claim 1, wherein there is further provided the step of dicing the silicon wafer along a direction substantially orthogonal to the longitudinal channel to expose a nozzle formed of the longitudinal channel.

13. The method of claim 1, wherein there is further provided the step of forming a heater over the longitudinal channel.

14. The method of claim 1, wherein there is further provided the step of forming integrated control circuitry in said silicon wafer.