Controlled gas generation for gas-driven infusion devices
First Claim
Patent Images
1. An article of manufacture comprising:
- a solid substance;
a liquid-retaining receptacle for retaining a liquid substance which upon contact with said solid substance generates a gaseous product, said liquid-retaining receptacle permitting contact of said liquid substance with said solid substance through diffusive transport of said liquid substance, said solid substance being external of said liquid-retaining receptacle and separated from the interior thereof by a receptacle wall having a passage therethrough; and
a wick in contact with said solid substance and extending through said passage into said interior of said receptacle for limiting diffusion of said liquid substance toward said solid substance to a controlled rate to achieve diffusion-controlled generation of said gaseous product, said wick comprised of a member selected from the group consisting of crosslinked polyvinyl alcohol and combinations of crosslinked polyvinyl alcohol and crosslinked polyvinyl acetate.
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Accused Products
Abstract
Gas is generated at a controlled rate from a liquid and solid phase combination that generated gas upon contact, by using diffusive transport of the liquid toward the solid phase surface to prolong the rate of gas generation, with a variety of alternatives for controlling the rate of diffusive transport. This system is useful in infusion devices for delivering medications or other beneficial liquids from a retaining pouch at controlled rates over a prolonged period of time.
102 Citations
32 Claims
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1. An article of manufacture comprising:
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a solid substance; a liquid-retaining receptacle for retaining a liquid substance which upon contact with said solid substance generates a gaseous product, said liquid-retaining receptacle permitting contact of said liquid substance with said solid substance through diffusive transport of said liquid substance, said solid substance being external of said liquid-retaining receptacle and separated from the interior thereof by a receptacle wall having a passage therethrough; and a wick in contact with said solid substance and extending through said passage into said interior of said receptacle for limiting diffusion of said liquid substance toward said solid substance to a controlled rate to achieve diffusion-controlled generation of said gaseous product, said wick comprised of a member selected from the group consisting of crosslinked polyvinyl alcohol and combinations of crosslinked polyvinyl alcohol and crosslinked polyvinyl acetate.
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2. An article of manufacture comprising:
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a molecular sieve impregnated with carbon dioxide; pores in said molecular sieve for retaining a liquid substance which upon contact with said molecular sieve generates a gaseous product, said pores permitting contact of said liquid substance with said molecular sieve through diffusive transport of said liquid substance; a liquid diluent combined with said liquid substance to form a solution for limiting diffusion of said liquid substance toward said solid substance to a controlled rate to achieve difflusion-controlled generation of said carbon dioxide. - View Dependent Claims (3, 4, 5, 6)
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7. An article of manufacture comprising:
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a molecular sieve impregnated with carbon dioxide; pores in said molecular sieve for retaining a liquid substance which upon contact with said molecular sieve generates a gaseous product, said pores permitting contact of said liquid substance with said molecular sieve through diffusive transport of said liquid substance; and a solute dissolved in said liquid substance to form a solution having a viscosity greater than that of said liquid substance alone. - View Dependent Claims (8, 9, 10)
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11. Apparatus for dispensing a liquid at a controlled rate, said apparatus comprising:
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a bladder to contain said liquid, said bladder containing an opening; a housing of substantially gas-impermeable wall material defining a cavity to receive said bladder while leaving said opening exposed; a solid substance and a liquid substance which upon contact with each other generate a gaseous product, said solid and liquid substances further received within said housing and external to said bladder, said liquid substance being retained within a liquid-retaining receptacle and said solid substance being external of said receptacle; a wick communicating said solid substance with the interior of said liquid receptacle and contacting said solid and liquid substances by diffusive transport of said liquid substance toward said solid substance at a controlled rate to achieve diffusion-controlled generation of said gaseous product, said wick comprised of a member selected from the group consisting of crosslinked polyvinyl alcohol and combinations of crosslinked polyvinyl alcohol and crosslinked polyvinyl acetate. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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20. Apparatus for dispensing a liquid at a controlled rate, said apparatus comprising:
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a bladder to contain said liquid, said bladder containing an opening; a housing of substantially gas-impermeable wall material defining a cavity to receive said bladder while leaving said opening exposed; a molecular sieve impregnated with carbon dioxide, and water, said molecular sieve and water further received within said housing and external to said bladder; and a liquid diluent combined with said water to form a solution, said liquid diluent causing diffusive transport of said water toward said molecular sieve at a controlled rate to achieve diffusion-controlled generation of said carbon dioxide. - View Dependent Claims (21)
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22. Apparatus for dispensing liquid at a controlled rate, said apparatus comprising:
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a bladder to contain said liquid, said bladder containing an opening; a housing of substantially gas-impermeable wall material defining a cavity to receive said bladder while leaving said opening exposed; a molecular sieve impregnated with carbon dioxide and water; and a solute dissolved in said water to form a solution having a viscosity greater than that of said water alone. - View Dependent Claims (23, 24)
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25. Apparatus for dispensing a liquid at a controlled rate, said apparatus comprising:
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a bladder to contain said liquid, said bladder containing an opening; a housing of substantially gas-impermeable wall material defining a cavity to receive said bladder while leaving said opening exposed; an aqueous liquid and a molecular sieve material with a gas adsorbed thereto, said aqueous liquid and said molecular sieve material both enclosed within said housing and positioned external to said bladder, whereby gas released from adsorption by said molecular sieve material upon contact of said aqueous liquid with said molecular sieve material causes compression of said bladder and consequently expulsion of liquid from said bladder through said opening.
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26. Apparatus for dispensing a liquid at a controlled rate, said apparatus comprising:
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a bladder to contain said liquid, said bladder containing an opening; a housing of substantially gas-impermeable wall material defining a cavity to receive said bladder while leaving said opening exposed; a liquid solution of a member selected from the group consisting of hydrogen peroxide and superoxide compounds, and a liquid absorbent material having immobilized thereon a member selected from the group consisting of catalysts and enzymes active in releasing oxygen gas from hydrogen peroxide and superoxide compounds, said liquid solution and said liquid absorbent material both enclosed within said housing and positioned external to said bladder, whereby gaseous oxygen released from said liquid solution causes compression of said bladder and consequently expulsion of liquid from said bladder through said opening. - View Dependent Claims (27, 28, 29, 30, 31, 32)
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Specification