Injection apparatus

• US 5,993,412 A
• Filed: 05/19/1997
• Issued: 11/30/1999
• Est. Priority Date: 05/19/1997
• Status: Expired due to Fees

• Current Assignee: Bioject Incorporated
• Original Assignee: Bioject Incorporated
• Inventors: Drach, Thomas J., Bunch, James J., Bonicatto, James M., Deily, Michael F.
• Primary Examiner(s): Coggins, Wynn Wood
• Assistant Examiner(s): KENNEDY, SHARON E
• Application Number:
  US08/858,249
• Time in Patent Office: 925 Days
• Field of Search: 128/DIG. 1, 604/50, 604/65, 604/67, 604/68, 604/70, 604/71, 604/98, 604/111, 604/131, 604/143, 604/146, 604/147, 604/208-210, 604/246
• US Class Current: 604/68
• CPC Class Codes: A61M 2005/208 Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
• CPC Class Codes: A61M 5/2053 Media being expelled from injector by pressurised fluid or vacuum for infusion A61M5/145, A61M5/155
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Abstract

The present invention typically is in the form of a needleless injector which includes the following components: (1) a needleless syringe installed in the injector for holding medication prior to injection, the syringe including an injection aperture at the forward end thereof; (2) a syringe plunger slidably mounted to the rear end of the syringe for forcing medication out the syringe aperture; (3) a syringe plunger drive mechanism providing power to drive the syringe plunger and thereby force medication out of the syringe; and (4) a syringe drive control mechanism for controlling the operation of the drive mechanism, the drive control mechanism including a warning system which warns the user if a pre-injection condition is not met, an interlock system which prevents injection from taking place if the pre-injection condition is not met, and a sensing system which senses whether the pre-injection condition is not met and conveys a signal to the warning and interlock systems informing as to whether the pre-injection condition is met.

Claims

1. A needleless injector comprising:

a needleless syringe installed in the injector for holding medication prior to injection, the syringe including an injection aperture at a forward end thereof;

a syringe plunger slidably mounted to a rear end of the syringe for forcing medication out of the syringe aperture;

a syringe plunger drive mechanism providing power to drive the syringe plunger and thereby force medication out of the syringe;

a drive control mechanism for controlling the operation of the drive mechanism, the drive control mechanism including a warning system which warns the user if any one of a plurality of pre-injection conditions is not met, an interlock system which prevents injection from taking place if any one of the plurality of pre-injection conditions are not met, and a sensing system which senses whether the plurality of pre-injection conditions is not met and conveys a signal to the warning and interlock systems informing as to whether all of the pre-injection conditions are met.

2. The injector of claim 1 wherein the sensing system senses whether the syringe is properly installed in the injector.

3. The injector of claim 2 wherein the system for sensing whether the syringe is properly installed includes a microswitch disposed adjacent the syringe which closes upon proper installation of the syringe, thereby deactivating the warning system and the interlock system and permitting injection.

4. The injector of claim 1 wherein the drive mechanism includes a compressed gas drive, and wherein the sensing system senses whether there is sufficient compressed gas pressure, and the interlock system prevents injection from taking place if there is insufficient compressed gas pressure.

5. The injector of claim 4, further comprising a sensor, and wherein the system for sensing whether there is sufficient compressed gas pressure and the interlock system for preventing injection if there is insufficient gas pressure include a pressure switch having a bellows which is displaceable based upon the compressed gas pressure, and a flag member mounted to the bellows which moves into and out of alignment with the sensor based upon the displacement of the bellows, and thereby controlling the activation of a signal in the event of inadequate pressure to the bellows.

6. The injector of claim 5 wherein the bellows is displaced a predetermined amount before the flag member is moved.

7. The injector of claim 1 wherein the drive control mechanism includes an electrical source for providing electrical power, wherein the sensing system senses whether the electrical source is providing sufficient power, and wherein the interlock system receives a signal from the sensing source to permit or prevent injection.

8. The injector of claim 1 wherein the sensing system senses whether there is sufficient medication in the syringe, and the interlock system prevents injection from taking place if there is insufficient medication in the syringe.

9. The injector of claim 8, wherein the interlock system for preventing injection when there is insufficient medication in the syringe includes a flag member, the position of which varies in relation to the position of the syringe plunger which directly corresponds to the amount of medication in the syringe, the flag member moving into and out of alignment with the sensor for sensing the position of the syringe, thereby controlling a signal in the event of insufficient medication in the syringe.

10. The injector of claim 9, further including a spring against which the syringe plunger is forced as the syringe is installed in the injector to expel any air therefrom.

11. The injector of claim 1 wherein the syringe plunger drive mechanism initially drives a first portion of the medication out of the syringe at a first, elevated pressure, and then drives a second portion of the medication out of the syringe at a lower, substantially constant, second pressure.

12. The injector of claim 11 wherein the syringe plunger drive mechanism includes a valve having a substantially planar face which lifts against the action of a spring when subjected to a predetermined gas pressure to provide the first pressure to the syringe, at which time the valve approaches a closed position and then oscillates in rapid succession to provide the second pressure to the syringe.

13. The injector of claim 1, wherein the drive mechanism provides a compressed gas drive to the syringe plunger.

14. The injector of claim 13 wherein the compressed gas drive is provided by a compressed gas cylinder, and further comprising a piercing pin mounted to the injector, and a compressed gas cartridge access door which opens to permit insertion of the cartridge into a cartridge receptacle defined in the injector, the access door also closing against a spring to effect relative movement between the cartridge and the piercing pin to pierce the cartridge.

15. The injector of claim 14 wherein the cartridge access door pivotally opens and closes, the closure of the door exerts a force on the cartridge to force the cartridge against the piercing pin, the spring being compressed further if a larger cartridge is used, and being compressed less if a smaller cartridge is used.

16. The injector of claim 14 wherein the piercing of the cartridge permits compressed gas to pass into a solenoid valve disposed in the injector, the opening of which permits compressed gas to drive the syringe plunger.

17. The injector of claim 16 wherein the solenoid includes a reciprocable piston which selectively seals a conduit and which compressed gas surrounds upon the piercing of the cartridge, and which when the solenoid valve is opened shifts to unseal the conduit to permit compressed gas to flow therethrough to drive the syringe plunger.

18. The injector of claim 17 further comprising a poppet valve mounted in the injector in fluid connection with the conduit, the poppet valve being selectively maintained in a closed position by a spring and wherein the opening of the solenoid valve causes compressed gas passing through the conduit to flow to the poppet valve and exert pressure thereon against the pressure of the spring, so that when a predetermined pressure is reached the poppet valve opens to permit a rush of compressed gas to flow therethrough to drive the syringe plunger.

19. The injector of claim 18 wherein the poppet valve spring pressure is set such that the rush of compressed gas through the poppet valve causes pressure on the poppet valve by the compressed gas to drop, causing the poppet valve to momentarily close, causing the compressed gas pressure on the poppet valve to be increased to open the poppet valve, and wherein this opening and closing occurs in rapid succession to provide a substantially constant, lower drive pressure to the plunger following the initial rush of compressed gas which provides a higher drive pressure to the plunger.

20. The injector of claim 13, further comprising a dose adjustment mechanism which permits the medication dosage to be adjusted.

21. The injector of claim 20 wherein the dose adjustment mechanism is in the form of a plunger drive piston which can be adjusted toward and away from the syringe to permit less or more medication, respectively, to be loaded into the syringe.

22. The injector of claim 21 wherein the plunger drive piston includes an axial slot with a plurality of contiguous circumferential slots, and a protrusion which can be guided into any of the circumferential slots and thereby control the position of the plunger with respect to the syringe to determine the amount of medication held in the syringe for subsequent injection.

23. The injector of claim 21, further comprising a dose compensator defining a dose compensation chamber which is enlarged and reduced as the amount of medication is decreased and increased, respectively, the dose compensation chamber being in fluid communication with the drive mechanism.

24. The injector of claim 1 wherein the drive mechanism provides compressed gas to drive the syringe, the injector further comprising an electric power source for providing power for controlling the operation of the injector, and wherein the plurality of pre-injection conditions include any one of the following:

insufficient compressed gas pressure;

insufficient electric power; and

insufficient medication in the injector.